Proliferation News and Research

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New cellular immunotherapy for cancers

A new study published in the journal Nature Communications on 22 October 2019 reports a new approach to cancer treatment that increases the immune capability of T lymphocytes against malignant cancers. This allows the T cells to successfully infiltrate and destroy these tumors. Animal trials have been completed and the researchers are planning clinical trials in human beings next.

26 Oct 2019

Scientists uncover how brain cells respond to and recover from lack of nutrition

We all know that food is essential to healthy development of the brain and body, especially in the earliest stages of life. But exactly how early brain growth is affected by nutrition is not as well understood, especially on a cellular level.

25 Oct 2019

Study reveals novel druggable driver gene in human gastrointestinal stromal tumors

Sarcomas - cancers that arise from transformed mesenchymal cells (a type of connective tissue) - are quite deadly. Gastrointestinal stromal tumors are the most common human sarcoma and are initiated by activating mutations in the KIT receptor tyrosine kinase.

24 Oct 2019

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson's and Alzheimer's diseases, and improves cognitive and motor behavior.

23 Oct 2019

Scientists take new step toward the goal of growing cell-based meat for human consumption

A team of Tufts University-led researchers exploring the development of cultured meat found that the addition of the iron-carrying protein myoglobin improves the growth, texture and color of bovine muscle grown from cells in culture.

22 Oct 2019

Link between pregnancy stress, immune activation, and postpartum depression

A new study presented at the Society for Neuroscience meeting on October 19, 2019, at Chicago, shows for the first time how postpartum depression could actually be due to abnormal immune system activation within the brain, which in turn is set off by chronic pregnancy stress. This is the earliest study to show this link in animals.

22 Oct 2019

Koalas protect their germline cells against retroviral attack

In a new study published in the journal Cell, scientists have found that koala DNA is protected against attack by retroviruses by a special type of immune response, which distinguishes foreign DNA from the host genome and destroys it before it can proliferate. This finding could help us understand both how koalas survive these infections, and the mechanics of adaptive gene change.

15 Oct 2019

Glycans in mucus are responsible for microbe-taming, study reveals

More than 200 square meters of our bodies -- including the digestive tract, lungs, and urinary tract -- are lined with mucus. In recent years, scientists have found some evidence that mucus is not just a physical barrier that traps bacteria and viruses, but it can also disarm pathogens and prevent them from causing infections.

14 Oct 2019

More sensitive electrophysiology tools needed to study cancer cell populations

Bioelectricity of Cancer, a special issue of the peer-reviewed journal Bioelectricity, has just been published. Two promising discoveries are well delineated: an ultra-sensitive tool to detect cancer and a new therapeutic target for cancer immunotherapy.

9 Oct 2019

Paclitaxel-coated devices used for widening blocked arteries not linked to increased mortality

Devices coated with a drug called paclitaxel that are used for widening blocked arteries in legs and feet are safe and not linked to an increase in deaths, according to a study of nearly 65,000 patients, published in the European Heart Journal today (Wednesday).

9 Oct 2019

New understanding of breast cancer metastasis to bone

In breast cancer patients with metastatic disease, bone is the most common site of metastasis and the most common site of first distant relapse, with roughly half (48%) of breast cancer patients developing bone metastases after treatment.

8 Oct 2019

Salford scientists identify new drug candidate to starve and suffocate breast cancer stem cells

Scientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for new therapies to treat breast cancer patients.

8 Oct 2019

Researchers identify proteins critical for spreading of breast cancer to bones

Once breast cancer spreads to bone, treatment becomes nearly impossible. Breast cancer cells can lie dormant in the bone, often undetectable and able to escape typical treatments.

7 Oct 2019

Scientists use organoid technology to achieve stable long-term cultures of mouse urothelial cells

Investigation of biological mechanisms in urothelial tissue -one of the three types of tissue that make up the urinary system- has always been very limited due to the lack of technologies that allow working with stable and long-term populations of the cells that compose it.

4 Oct 2019

GW researchers show connection between bacteria in the microbiome and colon cancer

A mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts of bacterial species associated with the development of colon cancer.

4 Oct 2019

Researchers are developing new therapy to counter the effects of traumatic brain injury

A blow to the head or powerful shock wave on the battlefield can cause immediate, significant damage to a person's skull and the tissue beneath it.

4 Oct 2019

Adding local anesthetics can improve treatment for incurable breast cancer, melanoma

A new study examined the effects of local anesthetics combined with standard chemotherapy for treatment of incurable triple-negative breast cancer, as well as melanoma.

3 Oct 2019

Researchers create new material with antifungal and antitumor properties

A new material with antifungal and antitumor properties has been developed by researchers at the Center for Development of Functional Materials (CDMF), one of the Research, Innovation and Dissemination Centers (RIDCs) supported by São Paulo Research Foundation - FAPESP.

3 Oct 2019

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

A clinical trial has shown that using a combination of three drugs that target a BRAF gene mutation in patients with mCRC effectively boosts overall survival.

30 Sep 2019

Researchers shed new light on how Toxoplasma parasite damages the human eye

One third of the world population is infected with the parasite -Toxoplasma- which causes a common eye infection called ocular toxoplasmosis. Researchers have shed new light on how an infection with the parasite causes a distinctive lesion in the retina.

30 Sep 2019

Proliferation News and Research

New cellular immunotherapy for cancers

Scientists uncover how brain cells respond to and recover from lack of nutrition

Study reveals novel druggable driver gene in human gastrointestinal stromal tumors

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Scientists take new step toward the goal of growing cell-based meat for human consumption

Link between pregnancy stress, immune activation, and postpartum depression

Koalas protect their germline cells against retroviral attack

Glycans in mucus are responsible for microbe-taming, study reveals

More sensitive electrophysiology tools needed to study cancer cell populations

Paclitaxel-coated devices used for widening blocked arteries not linked to increased mortality

New understanding of breast cancer metastasis to bone

Salford scientists identify new drug candidate to starve and suffocate breast cancer stem cells

Researchers identify proteins critical for spreading of breast cancer to bones

Scientists use organoid technology to achieve stable long-term cultures of mouse urothelial cells

GW researchers show connection between bacteria in the microbiome and colon cancer

Researchers are developing new therapy to counter the effects of traumatic brain injury

Adding local anesthetics can improve treatment for incurable breast cancer, melanoma

Researchers create new material with antifungal and antitumor properties

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

Researchers shed new light on how Toxoplasma parasite damages the human eye

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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