Efficacy News and Research

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A drug derived from an ocean-growing sponge helps prevent the growth of cancer cells

A drug derived from an ocean-growing sponge teams up to enhance the performance of the yew tree derivative Taxol® (paclitaxel) in preventing the growth of cancer cells, according to research published in the July 15 issue of the journal Cancer Research.

15 Jul 2004

New early breast cancer treatment significantly reduces the risk of cancer returning

Marking the first major treatment advance since tamoxifen's introduction over 25 years ago, Canada's leading oncologists and breast cancer patient support and advocacy groups gathered to applaud a new era in treatment for early breast cancer.

15 Jul 2004

Quality HIV/AIDS treatment eased through extended agreement about lowest-priced drugs and diagnostics

During the International AIDS Conference in Bangkok, IDA ARV Procurement Services BV and Clinton Foundation announced the agreement that enables developing countries to purchase high-quality AIDS medicines and diagnostics at the lowest available prices.

15 Jul 2004

Strategic analysis of the breast cancer therapeutics pipeline

Strategic partnerships between the pharmaceuticals industry and the biotechnology sector are making breast cancer therapeutics one of the most dynamic segments in the overall oncology market.

15 Jul 2004

Thalidomide's role in fighting blood disorders, such as multiple myeloma

From the late 1950s to the end of 1961, thalidomide was a popular sedative and treatment for morning sickness until it was discovered to cause fetal malformations, which proved fatal within the first year of life in 40 percent of affected infants.

13 Jul 2004

Latanoprost is safe as adjunctive therapy for long-term treatment of common form of glaucoma

Glaucoma is a condition in which the pressure inside the eyes rises. If untreated, glaucoma may damage the optic nerve and other parts of the eye, and my lead to blindness. According to information in the article, latanoprost is a derivative of the chemical prostaglandin F2-alpha. Prostaglandin derivatives have been shown to help lower intraocular pressure (IOP).

13 Jul 2004

Fluoxetine, orlistat, and sibutramine can diabetics achieve significant weight loss

According to information in the article, the prevalence of obesity in the United States increased from 12 percent in 1991 to 18 percent in 1998. Recent survey data indicate that 65 percent of Americans are overweight.

13 Jul 2004

Cell Therapeutics receives Fast Track Designation for Pixantrone, treatment for aggressive non-Hodgkin's lymphoma

Cell Therapeutics, Inc. has received fast track designation from the U.S. Food and Drug Administration (FDA) for pixantrone, a novel anthracenedione, being investigated for the potential treatment of relapsed, aggressive non-Hodgkin's lymphoma (NHL).

12 Jul 2004

Comparison of antiretroviral therapies shows that tenofovir DF and stavudine are equally effective

Results from a three year double-blinded trial which compared antiretroviral therapies show that the combination regimens of tenofovir DF and stavudine, are equally effective, though tenofovir DF has more favorable outcomes with respect to cholesterol levels and the nervous system.

11 Jul 2004

Nevirapine effective in reducing the risk of transmission of HIV at birth

A drug called nevirapine has been shown to be effective in reducing the risk of transmission of HIV at birth, but combination therapy of nevirapine and zidovudine does not improve outcomes, according to a study published in the current HIV/AIDS Journal of the American Medical Association.

11 Jul 2004

Cheap AIDS drugs may help prevent HIV in babies in Thailand

Aids is one of the principal causes of infant mortality in many developing countries. Viral transmission takes place during pregnancy (in utero), at the moment of childbirth or even during breastfeeding.

10 Jul 2004

Antidepressants should not be avoided in treatment of pregnant women with severe depression

Antidepressants to treat from moderate to severe depression in pregnant women not only are relatively safe but necessary in many cases for the well-being of the mother and the baby

7 Jul 2004

Endo announces agreement With FDA for new trial design of oxymorphone extended-release tablets

Endo Pharmaceuticals Inc., a wholly owned subsidiary of Endo Pharmaceuticals Holdings Inc., today announced that it has reached agreement with the U.S. Food and Drug Administration

7 Jul 2004

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Treatment with a new dual cell cycle and angiogenesis pathway inhibitor blocks VEGF-induced vascular permeability, inhibits tumour angiogenesis and induces apoptosis in human tumour models

7 Jul 2004

Anticoagulant therapy with enoxaparin is an effective alternative to heparin therapy for patients with acute coronary syndromes

Two new major studies suggest that anticoagulant therapy with enoxaparin is an effective alternative to heparin therapy for patients with acute coronary syndromes (ACS)

7 Jul 2004

NovoSeven may prove to be the first effective treatment for brain hemorrhage caused by stroke

Scientists from the UC Medical Center played a key role in developing what may prove to be the first effective treatment for brain hemorrhage caused by stroke.

5 Jul 2004

Medicine storage temperatures are too high

The recommended maximum storage and transit temperatures for most medications is 25°C and are set by the pharmaceutical manufacturers.

2 Jul 2004

Generic fixed-dose combinations (FDCs) of antiretrovirals are a key factor in access to treatment of HIV/AIDS infection in the developing world

Combination therapy with three generic antiretroviral drugs in a single tablet has been validated for the first time in an open clinical study in a developing country. Follow-up of 60 patients treated in Yaoundé, Cameroon, has demonstrated the excellent efficacy and safety of a generic fixed-dose combination.

2 Jul 2004

Access to HIV antiretroviral therapies in the developing world should be a major world health priority

One of the strategies adopted consists in utilizing combinations of fixed doses of generic antiretrovirals, involving three medicinal drugs of two different classes in the same tablet.

2 Jul 2004

Physical activity cuts risk of depression in children

Students who increase their physical activity during their middle-school years have fewer symptoms of depression, according to a new study.

1 Jul 2004

Efficacy News and Research

A drug derived from an ocean-growing sponge helps prevent the growth of cancer cells

New early breast cancer treatment significantly reduces the risk of cancer returning

Quality HIV/AIDS treatment eased through extended agreement about lowest-priced drugs and diagnostics

Strategic analysis of the breast cancer therapeutics pipeline

Thalidomide's role in fighting blood disorders, such as multiple myeloma

Latanoprost is safe as adjunctive therapy for long-term treatment of common form of glaucoma

Fluoxetine, orlistat, and sibutramine can diabetics achieve significant weight loss

Cell Therapeutics receives Fast Track Designation for Pixantrone, treatment for aggressive non-Hodgkin's lymphoma

Comparison of antiretroviral therapies shows that tenofovir DF and stavudine are equally effective

Nevirapine effective in reducing the risk of transmission of HIV at birth

Cheap AIDS drugs may help prevent HIV in babies in Thailand

Antidepressants should not be avoided in treatment of pregnant women with severe depression

Endo announces agreement With FDA for new trial design of oxymorphone extended-release tablets

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Anticoagulant therapy with enoxaparin is an effective alternative to heparin therapy for patients with acute coronary syndromes

NovoSeven may prove to be the first effective treatment for brain hemorrhage caused by stroke

Medicine storage temperatures are too high

Generic fixed-dose combinations (FDCs) of antiretrovirals are a key factor in access to treatment of HIV/AIDS infection in the developing world

Access to HIV antiretroviral therapies in the developing world should be a major world health priority

Physical activity cuts risk of depression in children

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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