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Tailored dose-dense chemotherapy does not improve breast cancer recurrence-free survival

Among women with high-risk early breast cancer, the use of tailored dose-dense chemotherapy compared with standard adjuvant chemotherapy did not result in a statistically significant improvement in breast cancer recurrence-free survival, and nonhematologic toxic effects were more frequent in the tailored dose-dense group, according to a study appearing in the November 8 issue of JAMA.

8 Nov 2016

ASH partners with other organizations to address knowledge gaps in AML care

The American Society of Hematology has partnered with several organizations on independent educational programming designed to help address knowledge gaps in the diagnosis and treatment of acute myeloid leukemia (AML).

8 Nov 2016

Caltech researchers develop new technique that increases safety of TCR gene therapy

The human body produces T cells to recognize and fight disease. Each T cell has a unique T cell receptor (or TCR) on its surface that surveils small fragments of proteins presented by other cells.

8 Nov 2016

Research reveals new molecular mechanisms of Huntington's disease

The research just published by a group of scientists from the Centre for Genomic Regulation (CRG) in Barcelona, Spain, led by Eulàlia Martí, in cooperation with researchers from the University of Barcelona (UB) and August Pi i Sunyer Biomedical Research Institute (IDIBAPS), has brought to light new information on the molecular mechanisms that cause Huntington’s disease, and defines new pathways to therapy discovery.

8 Nov 2016

Single gene therapy for lipoprotein lipase deficiency reduces severity and frequency of pancreatitis

Over a 6-year period, patients with the genetic disease lipoprotein lipase deficiency (LPLD) who received a single gene therapy treatment of alipogene tiparvovec had a marked reduction in the severity and frequency of pancreatitis.

8 Nov 2016

Researchers uncover possible targeted therapy for new, high-risk subtype of ALL

An international research team led by St. Jude Children's Research Hospital investigators has uncovered details of a new, high-risk subtype of acute lymphoblastic leukemia (ALL) as well as a possible targeted therapy.

8 Nov 2016

Second opinions may not reduce overtreatment in prostate cancer, study suggests

A new analysis indicates that many men with prostate cancer obtain second opinions from urologists before starting treatment, but surprisingly, second opinions are not associated with changes in treatment choice or improvements in perceived quality of prostate cancer care.

8 Nov 2016

Targeted precision medicine can eliminate cancer risk in patients with Type 2 diabetes

The links between Type 2 diabetes and cancer are complex: people suffering from diabetes mellitus essentially have a higher risk of developing cancer but, on top of that, some diabetes drugs are also suspected of increasing the risk in some cases.

8 Nov 2016

PENTAX Medical showcases latest innovations in endoscopy at UEGW 2016

PENTAX Medical highlighted “Quality in Focus: New Technologies Pushing Boundaries” at UEGW 2016, displaying its very latest endoscopic technology designed to support the clinical pathway through enhanced diagnosis and treatment.

8 Nov 2016

Study finds lack of improvement in health status of childhood cancer survivors

Long-term survivors of childhood cancer live longer thanks to improvements to cancer treatments, but a new study looking at three decades of therapy suggests patients do not report better health status.

8 Nov 2016

Scientists develop new computer-based method to assess cell communication networks

A multi-institution academic-industrial partnership of researchers led by Case Western Reserve University School of Medicine has developed a new method to broadly assess cell communication networks and identify disease-specific network anomalies.

8 Nov 2016

Biologic drugs may help prevent progressive bone loss in patients with RA

A new review by the International Osteoporosis Foundation Chronic Inflammation and Bone Structure Working Group concludes that early and aggressive treatment of Rheumatoid Arthritis (RA) with biologic drugs, specifically biological disease-modifying anti-rheumatic drugs (DMARDs), may be most effective in halting progressive bone loss in patients with RA.

7 Nov 2016

New treatment may reduce side effects linked to transfusions of red blood cells

A new treatment may diminish a dangerous side effect associated with transfusions of red blood cells (RBCs) known as pulmonary hypertension, an elevated blood pressure in the lungs and heart that can lead to heart failure, suggests a new study published in the November issue of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists.

7 Nov 2016

Scientists unravel viral molecular strategies to counter mammalian immune system

As mammals evolve, so do mammalian viruses. In doing so, they develop creative and effective ways to counter and evade the antiviral responses of their mammal hosts' immune systems.

7 Nov 2016

Gas-filled balloon capsules provide new low risk treatment option for patients with obesity

Patients with obesity who swallowed gas-filled balloon capsules designed to help them eat less, lost 1.9 times more weight than patients who relied on diet, exercise and lifestyle therapy alone, according to new research presented today at ObesityWeek 2016, the largest international event focused on the basic science, clinical application and prevention and treatment of obesity.

7 Nov 2016

Experts to discuss use of holograms and 3D printing at EuroEcho-Imaging 2016

EuroEcho-Imaging 2016 brings advanced techniques to the bedside with international experts set to discuss the use of holograms and 3D printing to guide interventions.

7 Nov 2016

New treatment with therapeutic short interfering RNA could help thwart cancer

In the fight against cancer, doctors dish out combination-blows of surgery, chemotherapy and other drugs to beat back a merciless foe. Now, scientists have taken early steps toward adding a stinging punch to clinicians' repertoire.

7 Nov 2016

Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

McMaster University researchers have found that for patients diagnosed in the late stages of one of the most common and deadly forms of skin cancer, treatment with a combination of immunotherapy options improves survival and lowers the risk of life-threatening events.

7 Nov 2016

Identifying gene defects may help develop individualised treatments for prostate cancer patients

The current method of treating prostate cancer involves identifying gene defects, which could help with the diagnosis of cancer and the development of individualised cancer treatments for patients.

7 Nov 2016

FDA approves new combo treatment for patients with advanced sarcomas

There are approximately 15,000 sarcoma cases annually in the United States, comprising more than 60 types of soft tissue sarcomas and 20 types of bony sarcomas.

7 Nov 2016

Therapy News and Research

Tailored dose-dense chemotherapy does not improve breast cancer recurrence-free survival

ASH partners with other organizations to address knowledge gaps in AML care

Caltech researchers develop new technique that increases safety of TCR gene therapy

Research reveals new molecular mechanisms of Huntington's disease

Single gene therapy for lipoprotein lipase deficiency reduces severity and frequency of pancreatitis

Researchers uncover possible targeted therapy for new, high-risk subtype of ALL

Second opinions may not reduce overtreatment in prostate cancer, study suggests

Targeted precision medicine can eliminate cancer risk in patients with Type 2 diabetes

PENTAX Medical showcases latest innovations in endoscopy at UEGW 2016

Study finds lack of improvement in health status of childhood cancer survivors

Scientists develop new computer-based method to assess cell communication networks

Biologic drugs may help prevent progressive bone loss in patients with RA

New treatment may reduce side effects linked to transfusions of red blood cells

Scientists unravel viral molecular strategies to counter mammalian immune system

Gas-filled balloon capsules provide new low risk treatment option for patients with obesity

Experts to discuss use of holograms and 3D printing at EuroEcho-Imaging 2016

New treatment with therapeutic short interfering RNA could help thwart cancer

Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

Identifying gene defects may help develop individualised treatments for prostate cancer patients

FDA approves new combo treatment for patients with advanced sarcomas

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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