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Negative pressure wound therapy effectively heals deep perivascular groin infections

Shorter wound healing time, fewer dressing changes and the opportunity for earlier discharge from the hospital.

14 Oct 2016

Crohn's disease appears to have two distinct genetic subtypes, study finds

Crohn's disease, a common inflammatory disorder of the intestinal tract, can have devastating consequences for a patient's quality of life and is notoriously hard to treat successfully, in part because its course and severity vary so much from one case to the next.

14 Oct 2016

WHO: Countries need to move much faster to prevent, detect and treat TB to meet global targets

New data published by the World Health Organization (WHO) in its 2016 Global Tuberculosis (TB) Report show that countries need to move much faster to prevent, detect and treat the disease if they are to meet global targets.

14 Oct 2016

Mount Sinai awarded $10 million grant to explore cellular, molecular mechanisms of GVHD

Researchers from the Icahn School of Medicine at Mount Sinai have been awarded a $10 million from the National Cancer Institute to explore the cellular and molecular mechanisms of acute graft-versus-host disease (GVHD), a common side effect that occurs after allogeneic bone marrow transplantation (BMT), and to develop novel therapeutic strategies for BMT patients with cancer that begin in the cells of blood-forming tissue or hematologic malignancies.

13 Oct 2016

Endocrine Society issues new guidelines on hypopituitarism

The Endocrine Society today issued a Clinical Practice Guideline that recommends treating insufficient hormone levels in individuals with hypopituitarism by replacing hormones at levels as close to the body's natural patterns as possible.

13 Oct 2016

Advanced Oncotherapy set to open first proton-beam cancer therapy unit in Harley Street, London

A pioneering cancer treatment that causes minimal damage to surrounding cells will soon be available in the UK for global cancer patients to access.

13 Oct 2016

URMC scientists receive award to explore new treatments for Huntington's disease

A new award from the CHDI Foundation will advance promising research that aims to slow the progression of Huntington's disease.

13 Oct 2016

New research reveals key protein involved in heart failure

A key protein that causes heart failure has been revealed through new research from a collaboration based in Kumamoto University, Japan.

13 Oct 2016

Clinical study to determine safety, efficacy of allogeneic CDCs for patients with myocardial infarction

A multi-center team of researchers are planning a clinical trial using cardiosphere-derived cells (CDCs) (a heterogeneous cluster of proliferating cardiac cells that include mesenchymal stem cells) to regenerate the tissue and improve function of the heart in patients who have suffered heart attacks (myocardial infarction, MI).

13 Oct 2016

RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

In a study using Real-time intraoperative magnetic resonance imaging (RT-IMRI) to guide the transplantation of induced pluripotent stem cell (iPSC)-derived neurons into the brains of non-human primates modeled with Parkinson's disease, researchers found that RT-IMRI guidance not only allows for better visualization and monitoring of the procedure, but also helps cell survival.

13 Oct 2016

Patients with hypothyroidism have nagging symptoms despite normal TSH tests, medication use

About 15 percent of the 10-12 million people in the U.S. with hypothyroidism, or an underactive thyroid, continue to feel sick despite following the standard of care recommended by the American Thyroid Association.

13 Oct 2016

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

Study to investigate clinical impact of new treatment for HFrEF patients

The academic partners in the VerICiguaT GlObal Study in Subjects with Heart Failure with Reduced EjectIon FrAction are pleased to announce that patient enrollment has begun.

12 Oct 2016

Study suggests possibility for small molecule drug/antibody combinatorial therapy to treat neuroblastoma

A study by a multidisciplinary team of researchers from The Saban Research Institute of Children's Hospital Los Angeles sheds further light on the role of the cytokine TGFβ1 in the growth of neuroblastoma, and suggests the possibility for a small molecule drug/antibody combinatorial therapy to treat this cancer.

12 Oct 2016

Study finds strong link between childhood adversity and bipolar disorder diagnosis

A University of Manchester study which looked at more than thirty years of research into bipolar, found that people with the disorder are 2.63 times more likely to have suffered emotional, physical or sexual abuse as children than the general population.

12 Oct 2016

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Results of preclinical studies by investigators at the Medical University of South Carolina reported in the August 2016 issue of Arthritis & Rheumatology demonstrate for the first time that including novel biomarkers in lupus nephritis (LN) prognostic models significantly increases their power to predict therapeutic efficacy.

12 Oct 2016

Novel microwave-induced photodynamic therapy could target deeply situated tumors

Physicists at The University of Texas at Arlington have shown that using microwaves to activate photosensitive nanoparticles produces tissue-heating effects that ultimately lead to cell death within solid tumors.

12 Oct 2016

Research on naked mole-rats could pave way for new human pain therapies

In injuries and inflammation, naked mole-rats do not develop normal hypersensitivity to temperature stimuli.

12 Oct 2016

Experts receive federal grant to improve mental health services for sexually exploited youth

A team of child welfare experts from the School of Public Health at Georgia State University and the Georgia Center for Child Advocacy has won a five-year, $2 million federal grant to provide higher quality mental health services to child victims of commercial sex trafficking.

12 Oct 2016

Aerobic exercise provides benefits to T1D patients on insulin pump therapy

Type 1 diabetes (T1D) patients on insulin pumps stand to benefit by engaging in aerobic exercise, said a team researchers who conducted a three-month observational study on two groups of diabetes patients.

12 Oct 2016

Therapy News and Research

Negative pressure wound therapy effectively heals deep perivascular groin infections

Crohn's disease appears to have two distinct genetic subtypes, study finds

WHO: Countries need to move much faster to prevent, detect and treat TB to meet global targets

Mount Sinai awarded $10 million grant to explore cellular, molecular mechanisms of GVHD

Endocrine Society issues new guidelines on hypopituitarism

Advanced Oncotherapy set to open first proton-beam cancer therapy unit in Harley Street, London

URMC scientists receive award to explore new treatments for Huntington's disease

New research reveals key protein involved in heart failure

Clinical study to determine safety, efficacy of allogeneic CDCs for patients with myocardial infarction

RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

Patients with hypothyroidism have nagging symptoms despite normal TSH tests, medication use

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

Study to investigate clinical impact of new treatment for HFrEF patients

Study suggests possibility for small molecule drug/antibody combinatorial therapy to treat neuroblastoma

Study finds strong link between childhood adversity and bipolar disorder diagnosis

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Novel microwave-induced photodynamic therapy could target deeply situated tumors

Research on naked mole-rats could pave way for new human pain therapies

Experts receive federal grant to improve mental health services for sexually exploited youth

Aerobic exercise provides benefits to T1D patients on insulin pump therapy

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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