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Unique progenitor cells in the pancreas have potential to develop glucose-responsive beta cells

Scientists from the Diabetes Research Institute at the University of Miami Miller School of Medicine have confirmed the existence of progenitor cells within the human pancreas that can be stimulated to develop into glucose-responsive beta cells.

28 Feb 2018

USC scientists use metal-detection technique to study cancer

Metal detection has helped mining companies strike gold and airport security identify passengers who are a potential threat. Now USC scientists have pushed its use into another realm: studying cancer.

28 Feb 2018

Study reveals cardiovascular health benefits of breastfeeding for some women

Women with normal blood pressure during pregnancy and who breastfed their babies for at least six months following birth had better markers of cardiovascular health years later compared to women who never breastfed, based on research presented at the American College of Cardiology's 67th Annual Scientific Session.

28 Feb 2018

Preeclampsia during pregnancy contributes to cardiovascular risk factors in women

Women diagnosed with preeclampsia during pregnancy were significantly more likely to develop high blood pressure, diabetes or high cholesterol within five years compared with women who did not have preeclampsia, in a study being presented at the American College of Cardiology's 67th Annual Scientific Session.

28 Feb 2018

Researchers devise novel approach to develop antibacterial drugs

Researchers at VIB, KU Leuven and UZ Leuven devised a novel approach to develop antibacterial drugs. With antibiotic resistance on the rise worldwide, such new drugs are urgently needed. The Flemish biotech spin-off Aelin Therapeutics will exploit the technology to produce new antibiotics for the clinic.

28 Feb 2018

Pancreatic progenitor cells could be used to treat diabetes, suggests study

Researchers have confirmed the existence of progenitor cells in the pancreas that can be stimulated to turn into glucose-responsive beta cells.

28 Feb 2018

CRISPR-like gene editing could be potential way to treat patients with harmful blood lipid levels

Using a variation of CRISPR gene editing may be a potential strategy for mimicking the protective effects of a genetic mutation linked to lower cholesterol levels and heart disease risks, according to new mouse research from the Perelman School of Medicine at the University of Pennsylvania published this week in Circulation.

28 Feb 2018

InSysBio evaluates tau protein phosphorylation related targets for treatment of AD

InSysBio continues to investigate the mechanisms underlying Alzheimer's disease using the quantitative systems pharmacology modeling approach. The part of QSP model describing tau protein was published in the PLOS ONE journal. This is one of more than dozen InSysBio publications in AD area during last seven years.

28 Feb 2018

Receptors crucial for establishing strong memories

When we create a memory, a pattern of connections forms between neurons in the brain. New work from UC Davis shows how these connections can be strengthened or weakened at a molecular level. The study is published Feb. 27 in the journal Cell Reports.

27 Feb 2018

Fresh insights into depression could pave way for new therapies

Fresh insights into changes in the brain linked to depression could pave the way for new therapies.

27 Feb 2018

New treatment shows promise to fight against serious inflammatory disease

Still's disease is a serious orphan disease manifested by high fevers, skin and joint involvement, including paralysis, as well as damage to other organs such as the liver or spleen. It is caused by a deregulation of the immune system triggering an acute inflammatory response.

27 Feb 2018

University of Guelph researcher discovers cause of nerve cell death in Parkinson's disease

A University of Guelph researcher has discovered one of the factors behind nerve cell death in Parkinson's disease, unlocking the potential for treatment to slow the progression of this fatal neurodegenerative disorder.

27 Feb 2018

Researchers develop new tool that provides 3D view of metabolic processes

An international team of researchers has developed a computational resource that provides a 3D view of genes, proteins and metabolites involved in human metabolism.

27 Feb 2018

Study uncovers special receptor that protects against asthma, allergies

A special receptor on cells that line the sinuses, throat and lungs evolved to protect mammals from developing a range of allergies and asthma, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

27 Feb 2018

Research reveals how mutant p53 enhances tumor metastasis

Scientists at The Wistar Institute have found a novel mechanism through which mutant p53 enhances metastasis by controlling tumor metabolism. The research, published online in Genes & Development, also revealed how this process is influenced by a naturally occurring p53 gene variant.

26 Feb 2018

Australian brings measles to New York sparking fears for unvaccinated

According to the city officials in New York, the small population of unvaccinated individuals need to be extra careful over the next couple of weeks because an Australian individual with suspected measles has arrived in the city. This announcement was made last Friday by the New York State Department of Health.

26 Feb 2018

University of Illinois at Chicago awarded $4.6 million NIH grant for chronic pain research

The University of Illinois at Chicago has been awarded a $4.6 million grant from the National Heart, Lung, and Blood Institute to study the molecular neurobiology of chronic pain in patients with sickle cell disease and to develop potential new drug treatments.

26 Feb 2018

New discovery may allow doctors to treat inflammation in neurodegenerative diseases

A new discovery about the immune system may allow doctors to treat harmful inflammation that damages the brain in neurodegenerative diseases such as Alzheimer's. It might also let doctors save patients from the potentially deadly inflammation of sepsis, a full-body infection that kills a quarter-million Americans every year.

26 Feb 2018

Researchers discover key inner control mechanism of cell's 'smart glue'

Researchers at St. Jude Children's Research Hospital have discovered that a protein critical to a process called liquid-liquid phase separation within the cell undergoes internal changes in conformation that are key to its function.

26 Feb 2018

Research reveals anti-cancer effects of natural extract from Daffodils

A research describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ULB, the researchers have discovered that this compound triggers the activation of an anti-tumoral surveillance pathway.

26 Feb 2018