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AHF: Lancet’s Africa AIDS study shows global testing woefully under-funded

A study published in the British medical journal Lancet yesterday suggesting that testing all adults in Africa annually for HIV and immediately treating every person who tests positive could halt the AIDS epidemic in Africa within a decade has spurred the AIDS Healthcare Foundation (AHF) to renew its call for the massive scale up of, and dramatically increased funding for global HIV testing and antiretroviral treatment worldwide.

26 Nov 2008

Selzentry (maraviroc) becomes fully approved HIV antiretrovial

The U.S. Food and Drug Administration (FDA) has granted Selzentry (maraviroc) full (traditional) approval for use in treatment-experienced adults with CCR5-tropic HIV-1 in combination with other antiretrovirals.

25 Nov 2008

AIDS advocates tell WHO: Stop harmful single-dose treatment for expectant mothers and infants

As World AIDS Day 2008 approaches, a coalition of hundreds of HIV/AIDS medical care providers and advocates, representing dozens of organizations, today sent a letter to Dr. Margaret Chan, Director General of the World Health Organization (WHO), urging an end to harmful single-dose HIV/AIDS treatment as a recommended treatment for expectant mothers and infants worldwide.

25 Nov 2008

Results out from first phase III randomized clinical trial to study the best time to begin ART in infants

Testing very young babies for HIV and giving antiretroviral therapy (ART) immediately to those found infected with the virus dramatically prevents illness and death, according to a report in the New England Journal of Medicine.

19 Nov 2008

Genetic Immunity announces first patient dosed in trial with DermaVir patch for HIV

Genetic Immunity, a US/Hungarian clinical-stage company focused on development of nanomedicines for targeted immune amplification, today announced it has treated the first subject in a Phase II clinical study to evaluate DermaVir Patch.

13 Nov 2008

Astragalus root plant chemical used to fight HIV

Like other kinds of cells, immune cells lose the ability to divide as they age because a part of their chromosomes known as a telomere becomes progressively shorter with cell division.

11 Nov 2008

Protein called TIM-3 turns off HIV-fighting T cells

In HIV-infected patients the body's immune system is unable to fight off the virus.

11 Nov 2008

Cells exhausted from fighting HIV infection can be rescued

Researchers at the University of Toronto and the University of California, San Francisco, have revealed new hope for HIV treatment with the discovery of a way to 'rescue' immune cells that are exhausted from fighting off HIV infection.

11 Nov 2008

Scientists engineer T cells to recognize HIV-1 strains that have evaded the immune system

The findings of the study, published online in the journal Nature Medicine, have important implications for developing new treatments for HIV, especially for patients with chronic infection who fail to respond to antiretroviral regimens.

10 Nov 2008

New tuberculosis vaccine safer, more effective than BCG vaccine for HIV-positive people

A new tuberculosis vaccine could be safer and more effective than the currently available BCG vaccine, particularly for HIV-positive people, according to a study to be published in the November issue of Infection and Immunity, IANS/Times of India reports (IANS/Times of India, 10/24).

28 Oct 2008

The sooner the better when it comes to HIV/AIDS treatment

New research into HIV/AIDS therapy has found that starting treatment with drugs for the AIDS virus may be better sooner than later as victims are more than 70% less likely to die when they started taking cocktails of HIV drugs earlier than currently recommended.

27 Oct 2008

CytoDyn files new IND for Cytolin

CytoDyn, Inc. has filed a new IND for a study to reconfirm dose ranging and to "prove the principle" with a randomized, double-blind placebo controlled study of Cytolin, the Company's first-in-class drug for treating HIV/AIDS. This comes 13 years after the first IND was issued for the drug.

22 Oct 2008

Researchers identify novel type of antibody that potently inhibits HIV infection

A small antibody fragment that is highly effective in neutralizing the human immunodeficiency virus (HIV) by preventing the virus from entering cells has been identified by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

21 Oct 2008

Antiretroviral drug efavirenz associated with better outcomes in HIV-infected adults

A study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that HIV-infected patients taking the antiretroviral drug efavirenz were more likely to adhere to treatment and less likely to experience virologic failure and death compared to patients taking nevirapine.

14 Oct 2008

HIV drug resistance spreading in China, researcher says

As HIV spreads beyond high-risk groups into China's general population, drug-resistant strains of the virus also are appearing in parts of the country, Chen Zhiwei of the AIDS Institute in Hong Kong said recently, Reuters reports.

13 Oct 2008

Drug companies plan to invest in HIV/AIDS drug development, improve access, U.N. Secretary-General says

United Nations Secretary-General Ban Ki-moon on Thursday said that many large pharmaceutical companies -- including Abbott Labs, Boehringer Ingelheim, GlaxoSmithKline and Pfizer -- plan to increase their efforts to develop HIV/AIDS drugs and diagnostics for impoverished regions, Reuters reports.

13 Oct 2008

Ukraine Parliament introduces bill to increase HIV prevention, treatment efforts

Ukraine's Parliament recently approved a bill that would establish a national program to increase HIV/AIDS prevention and treatment efforts in the country, Ukrainian News reports.

5 Oct 2008

Spiritual healing threatening adherence to antiretrovirals in Uganda, official says

Unverified spiritual healing promoted by some churches throughout Uganda is threatening HIV-positive patients' adherence to antiretroviral drugs, Robert Ochai, executive director of The AIDS Support Organisation, said recently during the organization's 17th annual general meeting, Uganda's Monitor reports.

5 Oct 2008

Newspapers examine efforts, reaction to easing ban on HIV-positive visitors to U.S.

Some HIV/AIDS advocates are "being cautious with their optimism" regarding new immigration rules for HIV-positive visitors as well as HHS efforts to remove HIV from the list of diseases barring entry into the U.S., the San Francisco Chronicle reports (Fulbright, San Francisco Chronicle, 10/2).

5 Oct 2008

Studies examine ability of antiretroviral Maraviroc to control HIV viral loads

According to two studies sponsored by drugmaker Pfizer and published in the New England Journal of Medicine on Wednesday, the antiretroviral drug maraviroc, which is sold as Selzentry by Pfizer, might help control viral loads among HIV-positive people who have shown resistance to other treatments, Reuters reports.

5 Oct 2008

Antiretroviral News and Research

AHF: Lancet’s Africa AIDS study shows global testing woefully under-funded

Selzentry (maraviroc) becomes fully approved HIV antiretrovial

AIDS advocates tell WHO: Stop harmful single-dose treatment for expectant mothers and infants

Results out from first phase III randomized clinical trial to study the best time to begin ART in infants

Genetic Immunity announces first patient dosed in trial with DermaVir patch for HIV

Astragalus root plant chemical used to fight HIV

Protein called TIM-3 turns off HIV-fighting T cells

Cells exhausted from fighting HIV infection can be rescued

Scientists engineer T cells to recognize HIV-1 strains that have evaded the immune system

New tuberculosis vaccine safer, more effective than BCG vaccine for HIV-positive people

The sooner the better when it comes to HIV/AIDS treatment

CytoDyn files new IND for Cytolin

Researchers identify novel type of antibody that potently inhibits HIV infection

Antiretroviral drug efavirenz associated with better outcomes in HIV-infected adults

HIV drug resistance spreading in China, researcher says

Drug companies plan to invest in HIV/AIDS drug development, improve access, U.N. Secretary-General says

Ukraine Parliament introduces bill to increase HIV prevention, treatment efforts

Spiritual healing threatening adherence to antiretrovirals in Uganda, official says

Newspapers examine efforts, reaction to easing ban on HIV-positive visitors to U.S.

Studies examine ability of antiretroviral Maraviroc to control HIV viral loads

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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