Immune System News and Research

RSS

Novel exosome-based drug delivery system for synergistic cancer treatment

Ovarian cancer is one of the most common malignancies in women worldwide. Unlike breast cancer, ovarian cancer lacks early diagnostic markers and does not show noticeable symptoms until cancer metastases, leading to a low survival rate for ovarian cancer patients.

12 Aug 2024

Study reveals how light-activated macrophages increase their appetite for cancer cells

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer.

12 Aug 2024

Engineered NK cells with IL-21 show strong antitumor activity against glioblastoma

Natural killer (NK) cells engineered to express interleukin-21 (IL-21) demonstrated sustained antitumor activity against glioblastoma stem cell-like cells (GSCs) both in vitro and in vivo, according to new research from The University of Texas MD Anderson Cancer Center.

12 Aug 2024

Study reveals how physical health impacts mental health via brain pathways

Multiple biological pathways involving organs and the brain play a key part in physical and mental health, according to a new study from UCL, the University of Melbourne and the University of Cambridge.

9 Aug 2024

Breakthrough study identifies intestinal epithelium's role in celiac disease gluten response

People with celiac disease must navigate everyday life by avoiding gluten, a protein in wheat, rye and barley which can trigger painful symptoms in the gut, impede the absorption of nutrients and raise the risk of other serious long-term issues.

9 Aug 2024

New diagnostic method enhances early detection of pancreatic cancer

Pancreatic cancer is one of the most lethal forms of cancer, primarily because it is usually diagnosed very late.

9 Aug 2024

Inflammation during pregnancy impacts child neurodevelopment

When a person experiences an injury or infection, the body's immune system responds with inflammation to start the healing process. However, inflammation can occur in much less helpful circumstances – for example, when a person experiences psychological stress or consistently eats a poor diet high in sugars, fats, and processed foods.

9 Aug 2024

Discovery of progenitor exhausted T cells offers hope for cancer patients

Tumor immunotherapy leverages the body's immune system to target and eradicate cancer cells, offering a crucial treatment for patients unresponsive to surgery or conventional therapies. Despite its potential, the effectiveness of immunotherapy is often hindered by T cell exhaustion within the tumor microenvironment, leading to diminished immune response and tumor progression. Based on these challenges, exploring the role of progenitor exhausted T cells (Tpex) in overcoming immune resistance is essential for advancing immunotherapeutic strategies and improving clinical outcomes.

8 Aug 2024

Gene activity can predict severe side effects from melanoma treatment

An activity pattern in certain genes responsible for building proteins known as spleen tyrosine kinases can predict which melanoma patients are likely to have severe side effects from immunotherapy designed to treat the most deadly skin cancer, a new study shows.

8 Aug 2024

Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

For decades, researchers have worked to develop therapies that can prime the immune system to recognize and attack proteins on the surface of tumor cells.

8 Aug 2024

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Using zebrafish "Avatars", an animal model developed by the Cancer Development and Innate Immune Evasion lab at the Champalimaud Foundation (CF), led by Rita Fior, Mayra Martínez-López – a former PhD student at the lab now working at the Universidad de las Américas in Quito, Ecuador – and colleagues studied the initial steps of the Bacillus Calmette-Guérin (BCG) vaccine's action on bladder cancer cells.

8 Aug 2024

Review of fasting-mimicking diets in cancer treatment

Researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy.

8 Aug 2024

SARS-CoV-2 protein linked to onset of multisystem inflammatory syndrome in children

St. Jude Children's Research Hospital scientists have identified a link between a SARS-CoV-2 protein and the onset of multisystem inflammatory syndrome in children (MIS-C).

7 Aug 2024

Study finds association between pesticide exposure and stillbirth risk

Living less than about one-third of a mile from pesticide use prior to conception and during early pregnancy could increase the risk of stillbirths, according to new research led by researchers at the Mel and Enid Zuckerman College of Public Health and Southwest Environmental Health Sciences Center.

7 Aug 2024

Nasal microbiome composition influences how well multi-resistant bugs can thrive in the nose

Whether dangerous staphylococci survive in the nose depends on what other bacteria are present - and how they obtain iron.

7 Aug 2024

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

Study reveals a mechanism behind multisystem inflammatory syndrome in children (MIS-C).

7 Aug 2024

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

7 Aug 2024

Discovery of Tr1 cells as a barrier to cancer immunotherapy offers new hope for treatment

Immunobiologists Robert Schreiber, PhD, (left) and Hussein Sultan, PhD, of Washington University School of Medicine in St. Louis, found that a subset of immune cells that normally puts the brakes on the immune system to prevent it from attacking the body's healthy cells inadvertently also dampens cancer immunotherapy.

7 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

Researchers uncover immune system barrier to cancer treatment

By recruiting the immune system to combat tumor cells, immunotherapy has improved survival rates, offering hope to millions of cancer patients. However, only about one in five people responds favorably to these treatments.

7 Aug 2024

Immune System News and Research

Novel exosome-based drug delivery system for synergistic cancer treatment

Study reveals how light-activated macrophages increase their appetite for cancer cells

Engineered NK cells with IL-21 show strong antitumor activity against glioblastoma

Study reveals how physical health impacts mental health via brain pathways

Breakthrough study identifies intestinal epithelium's role in celiac disease gluten response

New diagnostic method enhances early detection of pancreatic cancer

Inflammation during pregnancy impacts child neurodevelopment

Discovery of progenitor exhausted T cells offers hope for cancer patients

Gene activity can predict severe side effects from melanoma treatment

Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Review of fasting-mimicking diets in cancer treatment

SARS-CoV-2 protein linked to onset of multisystem inflammatory syndrome in children

Study finds association between pesticide exposure and stillbirth risk

Nasal microbiome composition influences how well multi-resistant bugs can thrive in the nose

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

Discovery of Tr1 cells as a barrier to cancer immunotherapy offers new hope for treatment

METRNL protein identified as key player in cancer progression

Researchers uncover immune system barrier to cancer treatment

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News