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Contaminant in cocaine impairs immune systems

Toxicologists across the country are sounding the alarm about a contaminant increasingly found in cocaine that is impairing cocaine users' immune systems, subjecting them to various infections and, in some cases, causing death.

26 May 2010

SCID added to the core panel of 29 genetic disorders

On May 21, 2010, Kathleen Sebelius, Secretary of Health and Human Services announced the addition of Severe Combined Immunodeficiency -- commonly known as bubble boy disease -- to the core panel of 29 genetic disorders -- as part of her recommendation to adopt the national Recommended Uniform Screening Panel.

26 May 2010

Study confirms effectiveness of CT for diagnosis of appendicitis

When CT results suggest appendicitis, but a patient's symptoms are inconsistent with the acute condition, physicians should consider a diagnosis of chronic or recurrent appendicitis and surgical treatment, according to a new study published in the online edition and July printed issue of the journal Radiology.

26 May 2010

NASH-induced cirrhosis is greater risk factor for HCC: Cleveland Clinic study

A study conducted by researchers at the Cleveland Clinic finds that patients suffering from cirrhosis preceded by nonalcoholic steatohepatitis are at an equal risk of developing hepatocellular carcinoma than those who develop cirrhosis resulting from hepatitis C virus. Results of this study appear in the June issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

26 May 2010

New technique designed to analyze individual immune cells may help diagnose food allergies: Study

About 30 percent of Americans believe they have food allergies. However, the actual number is far smaller, closer to 5 percent, according to a recent study commissioned by the National Institute of Allergy and Infectious Diseases. That's due in large part to the unreliability of the skin test that doctors commonly use to test for food allergies.

24 May 2010

Compatibility between donated kidney's weight and weight of recipient improves success of transplantation

Receiving an organ low in weight in relation to the recipient's body weight increases kidney transplant recipients risk of complications and transplant failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results suggest that compatibility between a donated kidney's weight and the weight of the recipient could improve the success of transplantation.

21 May 2010

Phase III PRIMA study data of Rituxan to be featured at 46th ASCO

Genentech, Inc., a wholly owned member of the Roche Group, and Biogen Idec today announced data from the Phase III PRIMA study.

21 May 2010

Eli Lilly to present results of two Phase II trials evaluating ALIMTA in combination with chemotherapy, radiation

Results of two Phase II trials evaluating ALIMTA (pemetrexed for injection) in combination with a platinum chemotherapy and radiation for patients with locally advanced non-small cell lung cancer will be presented by Eli Lilly and Company at the 46th Annual Meeting of the American Society of Clinical Oncology in Chicago, Ill., on June 6, 2010.

21 May 2010

Phase II study results of Lilly Oncology's tasisulam for metastatic melanoma to be presented at 46th ASCO

Lilly released results today from a Phase II study evaluating Lilly Oncology's tasisulam, a novel anti-cancer agent, in patients with metastatic melanoma, the deadliest form of skin cancer. Study results will be presented during the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO) held in Chicago, Ill. on June 6, 2010.

21 May 2010

New study reveals PTPN2 gene loss causes bone cancer

In patients with leukemia, the formation of white blood cells in the bone marrow is disrupted. This makes leukemia patients particularly susceptible to infections, because properly functioning white blood cells ensure protection against intruders such as viruses and bacteria.

21 May 2010

Phase I study of SNS-032 demonstrates safety, potential clinical activity in treating B-cell malignancies

A Phase I clinical trial of SNS-032, one of the first in a new class of drugs that inhibit cyclin-dependent kinases, demonstrated the drug's safety and potential clinical action against advanced chronic lymphocytic leukemia. Cyclin-dependent kinases are enzymatic proteins that are integrally involved in cellular metabolism, renewal and signaling, and are thought to play key roles in the growth of cancers.

20 May 2010

Newly-discovered watchmen DCs instruct T cells to attack and destroy cancer cells

Cancer Research UK scientists have discovered sophisticated 'watchman' cells in humans that can instruct the immune system to destroy foreign invaders like viruses and cancer cells, according to research published in The Journal of Experimental Medicine.

19 May 2010

Cincinnati Children's Hospital Medical Center launches REGID

A new nationwide registry will allow researchers to conduct larger, more effective studies of often misdiagnosed disorders that affect thousands of children in the United States.

19 May 2010

New multicenter trial achieves 71% survival in AML children

More individualized therapy and better supportive care helped push the survival for children with acute myeloid leukemia (AML) to 71 percent three years after diagnosis, according to new research led by St. Jude Children's Research Hospital investigators and reported in the medical journal The Lancet Oncology. The survival rate of 71 percent is 20 percent better than previously reported U.S. rates and is similar to the success achieved in a 2009 Japanese study, said Jeffrey Rubnitz, M.D., Ph.D., a member of the St. Jude Oncology department.

11 May 2010

New findings could help develop vaccines against respiratory infections

Inducing cellular immunity as a means to protect against influenza virus is the focus of several laboratories at the Trudeau Institute. Researchers here have recently identified two important signaling components required by the immune system that might allow us to pre-position our own virus-fighting T cells to the lungs, the site of initial infection.

11 May 2010

Ancient DNA sequences within human cells can help cancer cells survive: Study

A new study in the journal Nature Medicine, part-funded by Cancer Research UK, has discovered that ancient DNA sequences within human cells can actually help cancer cells survive - at least in one type of the disease.

7 May 2010

Resolvyx presents new data on RX-10001 for corneal herpes simplex virus infection at ARVO 2010

Resolvyx Pharmaceuticals, Inc., the leading resolvin therapeutics company, today announced the presentation of data on its novel resolvins for the treatment of both ocular surface diseases and retinal diseases at the Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting in Fort Lauderdale, Florida, being held May 2-6, 2010.

7 May 2010

Protein PEA-15 stops T-cell proliferation

New research has identified that a key protein called PEA-15 stops T-cell proliferation by blocking the cell's ability to reproduce. The control of T-cell proliferation is essential in preventing certain blood cancers and autoimmune diseases, as well as the orchestration of the immune response to infection. Findings of the study are reported in a recent online issue of The FASEB Journal, a publication of The Federation of American Societies for Experimental Biology.

5 May 2010

New pathology test may help doctors distinguish between two overlapping esophageal disorders: Study

A pathology test may help doctors distinguish between two separate but overlapping esophageal disorders that require different courses of treatment, according to a study by researchers at the University of North Carolina at Chapel Hill.

5 May 2010

Animal study shows insulin prevents artery damage

Long suspected of worsening artery damage in patients with diabetes, insulin instead protects blood vessels, a new study by Joslin Diabetes Center scientists indicates.

5 May 2010

Leukocyte News and Research

Contaminant in cocaine impairs immune systems

SCID added to the core panel of 29 genetic disorders

Study confirms effectiveness of CT for diagnosis of appendicitis

NASH-induced cirrhosis is greater risk factor for HCC: Cleveland Clinic study

New technique designed to analyze individual immune cells may help diagnose food allergies: Study

Compatibility between donated kidney's weight and weight of recipient improves success of transplantation

Phase III PRIMA study data of Rituxan to be featured at 46th ASCO

Eli Lilly to present results of two Phase II trials evaluating ALIMTA in combination with chemotherapy, radiation

Phase II study results of Lilly Oncology's tasisulam for metastatic melanoma to be presented at 46th ASCO

New study reveals PTPN2 gene loss causes bone cancer

Phase I study of SNS-032 demonstrates safety, potential clinical activity in treating B-cell malignancies

Newly-discovered watchmen DCs instruct T cells to attack and destroy cancer cells

Cincinnati Children's Hospital Medical Center launches REGID

New multicenter trial achieves 71% survival in AML children

New findings could help develop vaccines against respiratory infections

Ancient DNA sequences within human cells can help cancer cells survive: Study

Resolvyx presents new data on RX-10001 for corneal herpes simplex virus infection at ARVO 2010

Protein PEA-15 stops T-cell proliferation

New pathology test may help doctors distinguish between two overlapping esophageal disorders: Study

Animal study shows insulin prevents artery damage

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