Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Patients with early AD also have undiagnosed pre-diabetes, says Georgetown neurologist

When Georgetown University neurologist R. Scott Turner, MD, PhD, began enrolling people with mild to moderate Alzheimer's disease into a nationwide study last year, he expected to find only a handful of participants with undiagnosed glucose intolerance, as all the patients were already under a doctor's care and those with known diabetes were excluded.

15 Jul 2013

Research shows mutations in FAM190A gene may contribute to chromosomal instability in cancer

Johns Hopkins cancer scientists have discovered that a little-described gene known as FAM190A plays a subtle but critical role in regulating the normal cell division process known as mitosis, and the scientists' research suggests that mutations in the gene may contribute to commonly found chromosomal instability in cancer.

4 Jul 2013

Endoscopic imaging: an interview with Len Farris, Vice President of Marketing, Americas, PENTAX Medical

The impact of endoscopic imaging on patient care has been enormous since the first fiber optic systems were introduced more than 50 years ago. Today, high resolution and high definition systems are used to provide clinicians and patients unprecedented images from inside the body.

From PENTAX Medical Company 3 Jul 2013

New approaches to regenerate insulin-producing cells for type I diabetes

They have also shown that any pancreatic β cells can be regenerated several times and that chemically-induced diabetes in mice can thus be "treated" repeatedly. The challenge for the researchers is now to show that these procedures can be applied to humans.

28 Jun 2013

Study suggests amylin deposits are a new biomarker for age-related dementia and Alzheimer's

A second amyloid may play a role in Alzheimer's disease, UC Davis researchers find. A protein secreted with insulin travels through the bloodstream and accumulates in the brains of individuals with type 2 diabetes and dementia, in the same manner as the amyloid beta (Αβ) plaques that are associated with Alzheimer's disease, a study by researchers with the UC Davis Alzheimer's Disease Center has found.

28 Jun 2013

Curing type 1 diabetes: an interview with Dr. Habib Zaghouani, MU School of Medicine

Type 1 diabetes is an attack by the immune system of the islet of Langerhans within the pancreas. Basically, the islet of Langerhans harbor beta cells, which produce insulin and when the islets are attacked, the beta cells destruct and there is no more insulin. When the insulin level goes low, blood glucose levels go high and that creates a problem.

28 Jun 2013

Study: More people are being affected by drug-induced liver injury than ever before

More people are being affected by drug-induced liver injury (DILI) than ever before, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association.

27 Jun 2013

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

Two UC Irvine research groups have received $2.27 million from the JDRF to develop innovative methods of treating and possibly curing Type 1 diabetes.

27 Jun 2013

Promising approach to reduce risk of hypoglycemia in diabetes shows positive results

People with type 1 diabetes who rely on insulin injections to control their blood sugar levels are at risk for life-threatening hypoglycemic events in which their blood glucose levels drop dangerously low.

25 Jun 2013

Sanofi reports Phase 3 study of insulin U300 shows better blood sugar control than Lantus

Sanofi announced today that the first Phase 3 study results for its investigational new insulin U300 showed equivalent blood sugar control with fewer night-time low blood sugar events compared to Lantus.

24 Jun 2013

Linagliptin significantly reduces blood glucose levels in T2D patients with moderate to severe renal impairment

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announced results from a new study in which linagliptin demonstrated statistically significant reductions in blood glucose levels (HbA1c) after 12 weeks (the study's primary endpoint) in adults with type 2 diabetes (T2D) with moderate to severe renal impairment, compared with placebo. Most patients had T2D for more than ten years (76 percent) and were on insulin (86 percent).

24 Jun 2013

Scientists use stem-cell technology to create research cell line from PDAC patient

Pancreatic cancer carries a dismal prognosis. According to the National Cancer Institute, the overall five-year relative survival for 2003-2009 was 6 percent.

21 Jun 2013

Bristol-Myers Squibb and AstraZeneca announce top line results of Phase 4 SAVOR-TIMI-53 clinical trial of Onglyza

Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) today announced top line results of the Phase 4 SAVOR-TIMI-53 (Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus) clinical trial of Onglyza ® (saxagliptin).

20 Jun 2013

Study: Multiple islet autoantibodies in children indicate risk of developing type 1 diabetes

A decade-long JDRF-funded study led by the Institute of Diabetes Research in Helmholtz Zentrum M-nchen, Germany, is providing a deeper understanding of the link between autoantibodies and the risk of developing type 1 diabetes, highlighting the importance of pre-diabetes research into possible preventions for the disease.

20 Jun 2013

TEDDY study enables scientists to parse genetic mutations associated with type 1 diabetes

Massive samples emanating from a decade-old, international initiative to determine how genetics and environment cause type 1 diabetes are giving scientists a unique perspective on which molecular and environmental factors really contribute to the disease.

14 Jun 2013

15 minute walk after each meal appears to reduce risk of type 2 diabetes

A fifteen minute walk after each meal appears to help older people regulate blood sugar levels and could reduce their risk of developing type 2 diabetes, according to a new study by researchers at the George Washington University School of Public Health and Health Services (SPHHS).

12 Jun 2013

Countrywide study in Germany deems PRRT as life-prolonging treatment for patients with NETs

Peptide-receptor radionuclide therapy has been a subject of growing research on neuroendocrine tumors, which take up residence in a variety of organs replete with nerve cells that respond to hormone signaling.

12 Jun 2013

Clinical trial underway for potential new treatment for type 1 diabetes

A clinical trial is underway for a potential new treatment for type 1 diabetes that could eventually mean patients are able to reduce insulin treatment from several times a day to only once or twice a week. The new treatment is a direct result of research to understand the genetics of the disease.

11 Jun 2013

Cedars-Sinai opens Phase III clinical trial for patients with intestinal carcinoid cancer

Working to improve treatment and survivorship outcomes, the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute has opened a Phase III clinical trial of targeted radiation for patients with intestinal carcinoid cancer that has spread beyond the intestine.

10 Jun 2013

Rewinding the developmental state of embryonic stem cells is possible, say researchers

Scientists at the Danish Stem Cell Center, DanStem, at the University of Copenhagen have discovered that they can make embryonic stem cells regress to a stage of development where they are able to make placenta cells as well as the other fetal cells.

7 Jun 2013

Pancreas News and Research

Further Reading

Patients with early AD also have undiagnosed pre-diabetes, says Georgetown neurologist

Research shows mutations in FAM190A gene may contribute to chromosomal instability in cancer

Endoscopic imaging: an interview with Len Farris, Vice President of Marketing, Americas, PENTAX Medical

New approaches to regenerate insulin-producing cells for type I diabetes

Study suggests amylin deposits are a new biomarker for age-related dementia and Alzheimer's

Curing type 1 diabetes: an interview with Dr. Habib Zaghouani, MU School of Medicine

Study: More people are being affected by drug-induced liver injury than ever before

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

Promising approach to reduce risk of hypoglycemia in diabetes shows positive results

Sanofi reports Phase 3 study of insulin U300 shows better blood sugar control than Lantus

Linagliptin significantly reduces blood glucose levels in T2D patients with moderate to severe renal impairment

Scientists use stem-cell technology to create research cell line from PDAC patient

Bristol-Myers Squibb and AstraZeneca announce top line results of Phase 4 SAVOR-TIMI-53 clinical trial of Onglyza

Study: Multiple islet autoantibodies in children indicate risk of developing type 1 diabetes

TEDDY study enables scientists to parse genetic mutations associated with type 1 diabetes

15 minute walk after each meal appears to reduce risk of type 2 diabetes

Countrywide study in Germany deems PRRT as life-prolonging treatment for patients with NETs

Clinical trial underway for potential new treatment for type 1 diabetes

Cedars-Sinai opens Phase III clinical trial for patients with intestinal carcinoid cancer

Rewinding the developmental state of embryonic stem cells is possible, say researchers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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