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Children born of fathers exposed to nicotine inherit enhanced chemical tolerance, study shows

A father's nicotine use may have a significant impact on children's risk of some diseases. In a study published in the online biomedical sciences journal eLife, Oliver J. Rando, MD, PhD, and colleagues at UMass Medical School, demonstrate that mice born of fathers who are habitually exposed to nicotine inherit enhanced chemical tolerance and drug clearance abilities.

14 Feb 2017

Scientists managed to produce large quantities of promising natural substance

Once they can synthesise molecules of active natural substances, scientists will be able to harness nature’s medicine cabinet for the drugs of the future.

14 Feb 2017

New RNAi treatment safely blocks ocular inflammation in mice

Scientists have developed a new RNA interference therapeutic agent that safely blocked ocular inflammation in mice, potentially making it a new treatment for human uveitis and diabetic retinopathy.

14 Feb 2017

Taking prostate cancer drug with low-fat breakfast can be effective and less expensive, study finds

Taking one-fourth the standard dose of a widely used drug for prostate cancer with a low-fat breakfast can be as effective - and four times less expensive - as taking the standard dose as recommended: on an empty stomach.

14 Feb 2017

IBD patients have less stable gut microbiome than healthy people, study shows

Patients with inflammatory bowel disease are more likely to see dramatic shifts in the make-up of the community of microbes in their gut than healthy people, according to the results of a study published online Feb. 13 in Nature Microbiology.

13 Feb 2017

High-pressure culture of sports could increase risk of substance addiction among athletes, study finds

As she was planning her study to look into the role physical activity and sport play in the development of substance addiction, Laurie de Grace was forewarned that she may have trouble finding any recovering addicts with a sporting background to speak with.

13 Feb 2017

Scientists aim to create data mining tools to identify personalized treatment options for cancer

In the laboratories of Institute of Molecular Medicine Finland, drug testing is done ex vivo. That is, various leukemia drugs are tested with patient samples instead of the patients themselves. This enables the researchers to test different drug combinations efficiently and without burdening the patient.

13 Feb 2017

Scientists identify new biomarkers that could guide bowel cancer treatment

Colorectal carcinomas arise in different forms, so all treatments do not work for all patients. OncoTrack, a public-private consortium supported by the Innovative Medicines Initiative Joint Undertaking, has conducted one of Europe's largest collaborative academic-industry research projects to develop and assess novel approaches for identification of new markers for colon cancer.

13 Feb 2017

Professor aims to develop shortcuts for targeted and effective cancer therapy

The aim is to identify precisely the one drug, or the correct combination of drugs, that are most effective against the specific tumor present in each patient. Professor hopes that new tools will come into use in the next five years.

13 Feb 2017

Osmium-based compound seen to target cancer cells from inside

Researchers have witnessed - for the first time - cancer cells being targeted and destroyed from the inside, by an organo-metal compound discovered by the University of Warwick.

13 Feb 2017

Duke Health researchers identify potential new drug target for Huntington's disease

The loss of motor function and mental acuity associated with Huntington's disease might be treatable by restoring a cellular quality control process, which Duke Health researchers have identified as a key factor in the degenerative illness.

13 Feb 2017

Researcher finds new ways to adapt corn protein-based drug delivery method to pediatric medications

Developing medications for children can be challenging—taste and texture are important, but safety is also a major concern, according to pharmaceutical sciences professor Om Perumal at South Dakota State University.

13 Feb 2017

Scientists design new drugs that may help prevent spread of aggressive pancreatic cancers

Cancer is among the leading causes of death worldwide> There were approximately 14m new cases diagnosed and 8.2m cancer related deaths in 2012. This figure is expected to rise of about 70% over the next two decades.

13 Feb 2017

ACA urges patients to try non-drug approaches for back pain relief before taking NSAIDs

People suffering from back pain should consider first trying chiropractic services and other non-drug therapies in light of a new research review that found common over-the-counter and prescription pain medications have limited effectiveness for back pain and raise the risk of side-effects, according to the American Chiropractic Association.

13 Feb 2017

Study reveals new role for cancer drug in tumor immunology

A drug first designed to prevent cancer cells from multiplying has a second effect: it switches immune cells that turn down the body's attack on tumors back into the kind that amplify it. This is the finding of a study led by researchers from NYU Langone Medical Center and published recently in Cancer Immunology Research.

13 Feb 2017

New drug discovered in zebrafish model of pediatric epilepsy shows promising results in clinical study

"Bench-to-bedside" describes research that has progressed from basic science in animal models that has led to therapies used in patients.

13 Feb 2017

Study opens door to new opportunities for preventing and treating Alzheimer's disease

New research from Lund University in Sweden has shown that intestinal bacteria can accelerate the development of Alzheimer's disease.

11 Feb 2017

New drug offers hope for patients with bladder cancer

A bladder cancer drug discovered and developed at The University of Kansas Cancer Center is set to become its first cancer drug to go from bench to bedside.

10 Feb 2017

New laser-based camera could provide better view of carotid artery

Strokes and heart attacks often strike without warning. But, a unique application of a medical camera could one day help physicians know who is at risk for a cardiovascular event by providing a better view of potential problem areas.

10 Feb 2017

Natural emulsifier boosts antimicrobial properties of essential oil, eugenol

Lecithin, a natural emulsifier commonly used in processed foods, synergistically enhances the antimicrobial properties of the natural essential oil, eugenol, but only when applied in very small quantities. The research is published in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.

10 Feb 2017

Drugs News and Research

Children born of fathers exposed to nicotine inherit enhanced chemical tolerance, study shows

Scientists managed to produce large quantities of promising natural substance

New RNAi treatment safely blocks ocular inflammation in mice

Taking prostate cancer drug with low-fat breakfast can be effective and less expensive, study finds

IBD patients have less stable gut microbiome than healthy people, study shows

High-pressure culture of sports could increase risk of substance addiction among athletes, study finds

Scientists aim to create data mining tools to identify personalized treatment options for cancer

Scientists identify new biomarkers that could guide bowel cancer treatment

Professor aims to develop shortcuts for targeted and effective cancer therapy

Osmium-based compound seen to target cancer cells from inside

Duke Health researchers identify potential new drug target for Huntington's disease

Researcher finds new ways to adapt corn protein-based drug delivery method to pediatric medications

Scientists design new drugs that may help prevent spread of aggressive pancreatic cancers

ACA urges patients to try non-drug approaches for back pain relief before taking NSAIDs

Study reveals new role for cancer drug in tumor immunology

New drug discovered in zebrafish model of pediatric epilepsy shows promising results in clinical study

Study opens door to new opportunities for preventing and treating Alzheimer's disease

New drug offers hope for patients with bladder cancer

New laser-based camera could provide better view of carotid artery

Natural emulsifier boosts antimicrobial properties of essential oil, eugenol

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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