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Study helps identify optimal treatment option for NSCLC patients with brain metastases

A Yale Cancer Center team completed a multi-institutional analysis of treatment options for patients with newly diagnosed EGFR-mutant non-small cell lung cancer (NSCLC) with brain metastases to determine the best option for treatment.

28 Sep 2016

BREXIT vote threatens to disrupt advances in gene and cell therapies in the UK

The recent BREXIT vote in the UK threatens to disrupt scientific progress and clinical advances in the development of innovative gene and cell therapies.

28 Sep 2016

Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

A supplemental "boost" of radiation improves local control and provides an incremental benefit in decreasing breast cancer recurrence for patients with Ductal Carcinoma In Situ (DCIS) who receive whole breast radiation therapy radiation (WBRT) following lumpectomy, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

27 Sep 2016

Researchers link RHOX gene mutations to infertility in men

The underlying cause of male infertility is unknown for 30 percent of cases. In a pair of new studies, researchers at University of California San Diego School of Medicine determined that the reproductive homeobox (RHOX) family of transcription factors — regulatory proteins that activate some genes and inactivate others — drive the development of stem cells in the testes in mice.

27 Sep 2016

Study evaluates link between lowering LDL-C and CV risk reduction across statin and nonstatin therapies

In a study appearing in the September 27 issue of JAMA, Marc S. Sabatine, M.D., M.P.H., of Brigham and Women's Hospital, Harvard Medical School, Boston, and colleagues evaluated the association between lowering low-density lipoprotein cholesterol (LDL-C) and relative cardiovascular risk reduction across different statin and nonstatin therapies.

27 Sep 2016

Early endovascular thrombectomy plus medical therapy linked to less disability after stroke

In an analysis that included nearly 1,300 patients with large-vessel ischemic stroke, earlier treatment with endovascular thrombectomy (intra-arterial use of a micro-catheter or other device to remove a blood clot) plus medical therapy (use of a clot dissolving agent) compared with medical therapy alone was associated with less disability at 3 months, according to a study appearing in the September 27 issue of JAMA.

27 Sep 2016

New study highlights clinical and economic burden of NAFLD in the U.S. and Europe

Non-alcoholic fatty liver disease (NAFLD), the most common liver disease worldwide, is increasing in prevalence and is currently estimated to affect approximately one-quarter of the general population.

27 Sep 2016

Combination of different drugs could improve effect of immunotherapy on skin cancer

The results of studies involving researchers from the MedUni Vienna and Vienna General Hospital Comprehensive Cancer Center show that the effect of immunotherapy on malignant melanoma (black skin cancer) can be improved by combining it with other cancer treatments.

27 Sep 2016

New project clarifies molecular processes involved in hidden HIV reservoir

In spite of ever more effective therapies, HIV keeps managing to survive in the body. A comprehensive project conducted by the Austrian Science Fund FWF has clarified the molecular processes which contribute to this effect.

27 Sep 2016

Expectations of cancer patients may not match with actual results in phase I studies

In a study of cancer patients considering whether they should participate in phase I clinical trials, a high percentage were willing to participate after discussions with clinical staff, but nearly half thought that their tumors would shrink, which is much higher than what is realistically achieved.

27 Sep 2016

Super-Resolution Imaging of Biological Specimens

In this interview, News Medical speaks to Dr. Manasa Gudheti of Bruker Nano Surfaces about biological specimens and how to acquire super-resolution images of them.

From Bruker Nano Surfaces and Metrology 27 Sep 2016

Researchers identify process in the brains of mice that may explain repetitive actions in Rett patients

Three-year-old Naomi slaps her forehead a few times, bites her fingers and toddles across the doctor's office in her white and pink pajamas before turning her head into a door with a dull thud.

27 Sep 2016

Intermediate risk prostate cancer patients can achieve survival benefit with brachytherapy alone

For men with intermediate risk prostate cancer, radiation treatment with brachytherapy alone can result in similar cancer control with fewer long-term side effects, when compared to more aggressive treatment that combines brachytherapy with external beam therapy (EBT), according to research presented today at the 58th Annual Meeting the American Society for Radiation Oncology.

27 Sep 2016

New ABT approach results in greater weight loss than gold standard treatment, study shows

A new approach to weight loss called Acceptance-Based Behavioral Treatment (ABT) helped people lose more weight and keep it off longer than those who received only Standard Behavioral Treatment (SBT) - a typical treatment plan encouraging reduced caloric intake and increased physical activity - according to a new randomized controlled clinical trial.

27 Sep 2016

Increasing adoption of SBRT improves survival rates for older patients with early stage lung cancer

Survival rates for elderly patients who received stereotactic body radiation therapy (SBRT) for early stage non-small cell lung cancer (NSCLC) rose from roughly 40 to 60 percent over the past decade, concurrent with the increasing adoption of SBRT, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

27 Sep 2016

Endocrine Society Clinical Practice Guideline recommends CGMs for Type 1 diabetes patients

The Endocrine Society today issued a Clinical Practice Guideline recommending continuous glucose monitors (CGMs) as the gold standard of care for adults with Type 1 diabetes.

26 Sep 2016

IMRT reduces risk of side effects, improves quality of life for endometrial and cervical cancer patients

Patients with cervical and endometrial cancer have fewer gastrointestinal and genitourinary side effects and experience better quality of life when treated with intensity-modulated radiation therapy (IMRT) than with conventional radiation therapy (RT), according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

Therapy News and Research

Study helps identify optimal treatment option for NSCLC patients with brain metastases

BREXIT vote threatens to disrupt advances in gene and cell therapies in the UK

Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

Researchers link RHOX gene mutations to infertility in men

Study evaluates link between lowering LDL-C and CV risk reduction across statin and nonstatin therapies

Early endovascular thrombectomy plus medical therapy linked to less disability after stroke

New study highlights clinical and economic burden of NAFLD in the U.S. and Europe

Combination of different drugs could improve effect of immunotherapy on skin cancer

New project clarifies molecular processes involved in hidden HIV reservoir

Expectations of cancer patients may not match with actual results in phase I studies

Super-Resolution Imaging of Biological Specimens

Researchers identify process in the brains of mice that may explain repetitive actions in Rett patients

Intermediate risk prostate cancer patients can achieve survival benefit with brachytherapy alone

New ABT approach results in greater weight loss than gold standard treatment, study shows

Increasing adoption of SBRT improves survival rates for older patients with early stage lung cancer

Endocrine Society Clinical Practice Guideline recommends CGMs for Type 1 diabetes patients

IMRT reduces risk of side effects, improves quality of life for endometrial and cervical cancer patients

UCM REACT program receives $2 million federal grant to support children affected by violence

CNS experts create new research-based guidelines for evaluation and treatment of NFPAs

UNC secures $18 million NIH funding to form iTech for facilitating HIV research studies

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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