Respiratory News and Research

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Take Care Health Systems now offering nebulizer treatments for acute respiratory distress

Take Care Health Systems is now offering nebulizer treatments, when clinically appropriate, for clinic patients exhibiting acute respiratory distress.

6 Aug 2009

Aradigm receives orphan drug designation for inhaled liposomal ciprofloxacin to treat cystic fibrosis in Europe

Aradigm Corporation (OTCBB:ARDM) has announced that the European Medicines Agency (EMEA) granted Orphan Drug Designation to the Company’s inhaled liposomal ciprofloxacin drug product candidate for the treatment of lung infections associated with cystic fibrosis (“CF”).

6 Aug 2009

Less is more when it comes to blood transfusions

A new study suggests that blood transfusions for hospitalized cardiac patients should be a last resort because they double the risk of infection and increase by four times the risk of death.

5 Aug 2009

World Trade Center attack linked to new health problems years later

Large number of individuals, such as recovery and rescue workers, nearby residents and office workers, who experienced intense or prolonged exposure to the World Trade Center attack have reported new diagnoses of asthma or posttraumatic stress 5-6 years after the attack, according to a study in the August 5 issue of JAMA, a theme issue on violence and human rights.

4 Aug 2009

Divers who hold breath for several minutes elevate a marker for brain damage

Divers who held their breath for several minutes had elevated levels of a protein that can signal brain damage, according to a new study from the Journal of Applied Physiology. However, the appearance of the protein, S100B, was transient and leaves open the question of whether lengthy apnea (breath-holding) can damage the brain over the long term.

4 Aug 2009

Sleep heart health study

A study in the Aug. 1 issue of the journal Sleep indicates that self-reported worsening in initiating and maintaining sleep over a five-year period was significantly associated with poorer mental quality of life, and increasing daytime sleepiness symptoms were associated with both poorer physical and mental quality of life.

3 Aug 2009

FDA approves Onglyza (saxagliptin) for type 2 diabetes

The U.S. Food and Drug Administration has approved Onglyza (saxagliptin), a once-daily tablet to treat Type 2 diabetes in adults. The medication is intended to be used with diet and exercise to control high blood sugar levels.

2 Aug 2009

Research suggests that zinc activates a key protein on T cells needed to fight infections

Everyone knows that vitamins "from A to zinc" are important for good health. Now, a new research study in the August 2009 print issue of the Journal of Leukocyte Biology suggests that zinc may be pointing the way to new therapeutic targets for fighting infections.

31 Jul 2009

Repeated stress signals made in cells with metabolism-associated disease encourage the growth of invading bacteria

Mitochondrial diseases disrupt the power generating machinery within cells and increase a person's susceptibility to bacterial infection, particularly in the lungs or respiratory tract.

28 Jul 2009

Ozone exposure even at normal levels has negative effect on lung function

Ozone exposure, even at levels deemed safe by current clean air standards, can have a significant and negative effect on lung function, according to researchers at the University of California Davis.

26 Jul 2009

Emphysema severity directly linked to exposure to respirable coal mine dust

Coal dust exposure is directly linked to severity of emphysema in smokers and nonsmokers alike, according to new research from the National Institute for Occupational Safety and Health (NIOSH).

26 Jul 2009

Global health officials working to prevent H1N1 spread

"Global health officials are scrambling to try to prevent the spread of the H1N1 swine flu virus, with U.S. officials moving Thursday with a recommendation that the Food and Drug Administration (FDA) approve or license a [new H1N1] vaccine," without waiting on the results from "clinical trials to test its safety and efficacy," Wall Street Journal reports (Dooren/Winning, 7/24).

24 Jul 2009

FDA authorizes emergency use of another test for H1N1 flu virus

The U.S. Food and Drug Administration today announced it has issued an Emergency Use Authorization (EUA) for a another diagnostic test for the 2009 H1N1 influenza virus, whose spread has caused the virus to be characterized as a pandemic by the World Health Organization.

24 Jul 2009

Miglustat shows promise for cystic fibrosis

Miglustat is a drug currently under phase 2 clinical trials on patients suffering from cystic fibrosis (1). Its potential for treating the disease was discovered in 2006 thanks to the work of Frédéric Becq's team at the Institute of Cell Physiology and Biology (CNRS/Université de Poitiers), funded by the associations Vaincre la Mucoviscidose, MucoVie66, La Pierre Le Bigaut and ABCF2.

21 Jul 2009

Rates of secondhand smoke exposure high among college students

Secondhand smoke (SHS) is not only a nuisance, but a potential health concern for many college students, and administrators should be taking steps to reduce students' exposure, according to a new study by researchers at Wake Forest University School of Medicine.

21 Jul 2009

A quantum dot-based method for analysis of DNA methylation

One of the earliest events that changes a normal cell into a malignant one is known as deoxyribonucleic acid (DNA) hypermethylation, a biochemical alteration that inactivates critical tumor-suppressor genes.

21 Jul 2009

Depression and stress worsen childhood asthma

Young people with asthma have nearly twice the incidence of depression compared to their peers without asthma, and studies have shown that depression is associated with increased asthma symptoms and, in some cases, death.

17 Jul 2009

WHO gives up counting swine flu cases

In its latest briefing on the H1N1 influenza A pandemic (swine flu), the World Health Organisation (WHO) says the unprecedented speed of the spread of the virus means reporting requirements and the data needed for risk assessment, both within affected countries and at the global level, are changing.

16 Jul 2009

Discovery of new transmission patterns may help prevent diarrhea-causing disease rotavirus

New vaccines have the potential to prevent or temper epidemics of the childhood diarrhea-causing disease rotavirus, protect the unvaccinated and raise the age at which the infection first appears in children, federal researchers reported in a study today.

16 Jul 2009

Schering-Plough expands Vicriviroc study in treatment-naive patients with HIV

Schering-Plough Corporation has announced that it has extended to stage two an ongoing Phase II clinical study with vicriviroc, its investigational CCR5 antagonist, for use in first-line therapy of adult treatment-naive HIV-infected patients with R5-type virus only. In this study, vicriviroc is being evaluated in a novel nucleoside-sparing regimen that is designed to provide additional options for treatment-naive patients in a once daily regimen, while preserving other drug classes for subsequent lines of treatment.

15 Jul 2009