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Machine learning and proteomics predict cardiovascular risk more accurately

An innovative proteomics-based model that predicts the risk of cardiovascular events with higher accuracy than current clinical models.

10 Apr 2022

MOFs could help improve the delivery of genetic cargo into target cells

Hybrid material helps ferry genetic cargo to target cells. An emerging type of material called a metal-organic framework(MOF) could help improve the delivery of genetic material for treating disease.

10 Apr 2022

NK cells complexed with bispecific antibody elicit high response rate in patients with resistant lymphomas

Natural killer (NK) cells derived from cord blood that were activated and complexed with a CD30/CD16A bispecific antibody elicited an 89 percent overall response rate in patients with relapsed or refractory CD30+ lymphoma, according to results from a phase I/II clinical trial presented at the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Novel therapy advances to clinical trial for the treatment of glioblastoma

A novel therapy studied at the Medical College of Wisconsin (MCW) Cancer Center has led to a clinical trial for the treatment of glioblastoma, a rare and aggressive form of brain cancer, yet the most common primary brain tumor in adults.

10 Apr 2022

B-cells have significant differences in women with postpartum depression, finds study

A study published in Molecular Psychiatry is the first to look at multiple levels of biology within women with postpartum depression (PPD) to see how women with the condition differ from those without it.

10 Apr 2022

Simple interventions reduced radiation exposure to the heart during lung cancer treatment

Radiation to the heart during treatment for locally advanced lung cancer is associated with an increased risk of major adverse cardiac events within the first two years following treatment. The higher the cardiac dose exposure, the higher the risk of a cardiac event.

8 Apr 2022

Researchers seek to understand how microbes in the GI tract help people resist pathogens

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

8 Apr 2022

Advanced microscopy reveals exciting insights into dynamic ultrastructure of the heart

What happens below the cellular level when the heart contracts and relaxes has long been unexplored. Thanks to new ultra-high-resolution electron microscopy techniques, scientists can now watch the heart beating – almost at a molecular level.

8 Apr 2022

Imbalances in the intestinal virome may promote inflammatory bowel disease, research shows

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

8 Apr 2022

New delivery method enhances the "attack power" of CAR T cells against tumors

One cutting-edge cancer treatment exciting researchers today involves collecting and reprogramming a patient's T cells – a special set of immune cells – then putting them back into the body ready to detect and destroy cancerous cells.

8 Apr 2022

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea.

8 Apr 2022

Expanding statin prescription could be a cost-effective intervention against cardiovascular disease

Expanding prescription of statin medication to reduce low-density lipoprotein cholesterol could be a cost-effective intervention against cardiovascular disease, according to a Northwestern Medicine study published in the journal Circulation.

8 Apr 2022

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

New findings from the ongoing Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study suggest that certain rheumatoid arthritis drugs may lower incidence of Alzheimer's disease and related dementias in people with cardiovascular disease.

8 Apr 2022

Study: Many older adults are not prescribed disease-modifying drugs for rheumatoid arthritis

Despite guidelines that call for early and aggressive treatment of rheumatoid arthritis, a new study suggests many older adults are not prescribed disease-modifying medications for their inflammatory autoimmune disease.

8 Apr 2022

Researchers develop new method to ‘time jump’ skin cells by 30 years

Research from the Babraham Institute has developed a method to 'time jump' human skin cells by 30 years, turning back the aging clock for cells without losing their specialized function.

8 Apr 2022

Study on the viral dynamics of Omicron and Delta infected individuals

Researchers examine the infectious periods in vaccinated individuals infected with the SARS-CoV-2 Omicron and Delta variants.

7 Apr 2022

Primordial germ cell-like cells generated from rat stem cells enable the birth of normal offspring

Primordial germ cell-like cells (PGCLCs), generated in vitro from the stem cells of rats, undergo gametogenesis in vivo and yield normal rat offspring, a new study demonstrates.

7 Apr 2022

Mutant mice with a human gene variant exhibits ADHD-like problems

Mutant mice are providing scientists with a new neurobiological framework to understand the brain changes observed in distractible humans who carry a common gene variant whose frequency has been associated with Attention Deficit Hyperactivity Disorder (ADHD).

7 Apr 2022

Modified version of hormone kisspeptin can be used to treat non-alcoholic fatty liver disease

A hormone that triggers puberty and controls fertility in humans might be developed as a treatment for non-alcoholic fatty liver disease, according to new Rutgers research.

7 Apr 2022

NHLBI researchers support multiple programs to address pregnancy-related health disparities

During Black Maternal Health Week, April 11-17, and in preparation for Women's Health Month in May, researchers are raising awareness about pregnancy-related complications that disproportionately affect Black people.

7 Apr 2022

Medicine News and Research

Machine learning and proteomics predict cardiovascular risk more accurately

MOFs could help improve the delivery of genetic cargo into target cells

NK cells complexed with bispecific antibody elicit high response rate in patients with resistant lymphomas

Novel therapy advances to clinical trial for the treatment of glioblastoma

B-cells have significant differences in women with postpartum depression, finds study

Simple interventions reduced radiation exposure to the heart during lung cancer treatment

Researchers seek to understand how microbes in the GI tract help people resist pathogens

Advanced microscopy reveals exciting insights into dynamic ultrastructure of the heart

Imbalances in the intestinal virome may promote inflammatory bowel disease, research shows

New delivery method enhances the "attack power" of CAR T cells against tumors

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Expanding statin prescription could be a cost-effective intervention against cardiovascular disease

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

Study: Many older adults are not prescribed disease-modifying drugs for rheumatoid arthritis

Researchers develop new method to ‘time jump’ skin cells by 30 years

Study on the viral dynamics of Omicron and Delta infected individuals

Primordial germ cell-like cells generated from rat stem cells enable the birth of normal offspring

Mutant mice with a human gene variant exhibits ADHD-like problems

Modified version of hormone kisspeptin can be used to treat non-alcoholic fatty liver disease

NHLBI researchers support multiple programs to address pregnancy-related health disparities

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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