Atomic Force Microscopy News and Research

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Atomic force microscopy is a type of scanning probe microscopy used to image the surface of a substance, but at an atomic level. It can map the surface structure of different substances to understand how different structures interact with each other. This is done using a cantilever, which is similar to a vinyl record needle.

LYSOGENE launches the first gene therapy clinical trials in Sanfilippo disease

LYSOGENE announces the authorization by AFSSAPS (the French Agency for the Safety of Health Products) and by the Ethical Review Board of SAF-301, its leading intra-cerebral gene therapy phase I/II clinical trial aiming at treating Sanfilippo Type A Syndrome.

16 Aug 2011

Bruker second quarter revenue increases 33% y-o-y to $401.2 million

Bruker Corporation today reported financial results for the three and six months ended June 30, 2011.

3 Aug 2011

FDA approves U.S. launch of Wiskott-Aldrich gene therapy clinical trial

The U.S. Food & Drug Administration (FDA) approved the launching in the U.S. of a clinical trial for gene therapy for a rare immunodeficiency, Wiskott-Aldrich syndrome.

22 Jul 2011

Researchers use AFM to characterize ovarian cell structure for cancer diagnosis

Using ovarian surface epithelial cells from mice, researchers from Virginia Tech have released findings from a study that they believe will help in cancer risk assessment, cancer diagnosis, and treatment efficiency in a technical journal: Nanomedicine.

7 Jul 2011

Ovarian cells are stiffer and more viscous when benign

6 Jul 2011

Bruker launches new FastScan Atomic Force Microscope

Bruker today announced the innovative and unique Dimension FastScan Atomic Force Microscope, which delivers a significant breakthrough in improved imaging speed without sacrificing nanoscale resolution.

From Bruker Nano Surfaces and Metrology 3 May 2011

AMT 2010 total net income increases to EUR 1.4 million

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, today reported its results for the year to December 31, 2010.

16 Feb 2011

Protein cross-linking enzymes in foods can affect physiological characteristics

Protein modification via enzymatic cross-linking is an attractive way for altering food structure so as to create products with increased quality and nutritional value. These modifications are expected to affect not only the structure and physico-chemical properties of proteins but also their physiological characteristics, such as digestibility in the GI-tract and allergenicity.

10 Feb 2011

Genethon deploys Atempo Digital Archive to optimize biotherapy research data storage resources

Atempo, a leading provider of cross-platform data protection and archiving solutions, announced today that Genethon, a French non-profit biotherapy research center, has deployed Atempo Digital Archive, Atempo's advanced file archiving platform, to optimize its storage resources.

12 Jan 2011

AMT enters agreement with Consortium for clinical development of novel gene therapy to treat Sanfilippo B

Amsterdam Molecular Therapeutics, a leader in human gene therapy, announced today that it has entered into an agreement with Institut Pasteur, Paris, France, and a group of French research institutes (together the "Consortium") to support clinical development of a novel gene therapy to treat Sanfilippo B.

10 Jan 2011

Progress update on Johnson & Johnson and Crucell's public offer

Pursuant to the provisions of Section 7 paragraph 1(a) of the Dutch Decree on Public Takeover Bids (Besluit Openbare Biedingen Wft) requiring a public announcement within four weeks following the announcement of an intended public offer to provide a status update, Johnson & Johnson (NYSE: JNJ) and Crucell N.V. provide the following joint update.

30 Oct 2010

Bruker closes acquisition of instruments businesses with Veeco

Bruker Corporation today announced the closing of its acquisition of the Atomic Force Microscopy (AFM) and the Optical Industrial Metrology (OIM) instruments businesses from Veeco Instruments, Inc. for $229.4 million in cash.

8 Oct 2010

New squeeze test for screening potential drugs for Alzheimer's

Brain cells exposed to a form of the amyloid beta protein, the molecule linked to Alzheimer's disease, become stiffer and bend less under pressure, researchers at UC Davis have found. The results reveal one mechanism by which the amyloid protein damages the brain, a finding that could lead to new ways to screen drugs for Alzheimer's and similar diseases.

21 Aug 2010

WPI researchers measure molecular forces that enable cranberry juice to fight off urinary tract infections

Revealing the science behind the homespun advice, a team of researchers at Worcester Polytechnic Institute (WPI) has identified and measured the molecular forces that enable cranberry juice to fight off urinary tract infections in people.

16 Jul 2010

Institute of Food Research unveils new emulsifier technique

New work from the Institute of Food Research has shown how sugar beet pectin acts as an efficient emulsifier, using a technique that could be used to unravel in the finest detail how such important food ingredients work.

2 Jul 2010

Pharnext closes €4.8-million Series A funding round

Pharnext SAS, a biopharmaceutical company specializing in the development of innovative treatments based on Pleotherapy™ for severe neurological diseases, today announced that it had closed a €4.8-million Series A round of funding on June 3rd (corresponding to a company valuation of €45 million).

9 Jun 2010

Bruker to supply customized N8 TITANOS large sample AFM to US Commerce Department's NIST

Bruker today announced that it has been awarded a $1.1 million contract to supply a customized N8 TITANOS™ large sample Atomic Force Microscope (AFM) to the United States Commerce Department's National Institute of Standards and Technology (NIST). The instrument will be used by NIST's Precision Engineering Division (PED) at its Manufacturing Engineering Laboratory, with a main focus on metrology applications which require traceable AFM (T-AFM).

26 Apr 2010

Structure of Amyloid fibers surprises researchers

The Atomic Force Microscope depicts on its screen the few nanometer thick and few micrometer long fibers as white flexible sticks, crisscrossing the surface on which they are deposited. The very peculiar property of these proteins lies in fact that they can self assemble into complex ribbon-like twisted fibers.

19 Apr 2010

Some therapies being investigated for Alzheimer's disease may cause cell death: UCSD

Some current therapies being investigated for Alzheimer's disease may cause further neural degeneration and cell death, according to a breakthrough discovery by UC San Diego researchers. By combining three dimensional computer simulations with high resolution atomic force microscopy membrane protein and cell imaging, electrical recording and various cellular assays, UCSD nano-biophysicist Ratnesh Lal and his colleagues investigated the structure and function of truncated peptides, known as nonamyloidgenic peptides, formed by some Alzheimer's drug candidates.

5 Apr 2010

Etch recipe allows engineers and product developers to design diamond devices

Advanced Diamond Technologies (ADT) is making broadly available an etch recipe which enables engineers and product developers to reliably and affordably design micro devices and sensors out of diamond.

4 Feb 2010