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Indiana University researcher helps develop FDA-approved Alzheimer’s test

A first-of-its-kind blood test to detect amyloid plaques in the brain associated with Alzheimer's disease recently received clearance from the U.S. Food and Drug Administration. An Indiana University School of Medicine researcher who helped lead the discovery and development of one of the biomarkers the test identifies hopes it will provide greater access and a more accurate diagnosis for patients.

16 Jun 2025

Bringing microbiome science into everyday clinical care

The article summarizes results of research and possible future clinical applications of the microbiome and provides instructions for doctors.

13 Jun 2025

Lynch syndrome testing often missed in womb cancer patients

Patients with womb cancer are not being tested for a genetic condition that increases their chance of developing further cancers, a study has found.

9 Jun 2025

Blood test shows high accuracy in detecting Alzheimer's disease

Alzheimer's disease, marked by memory loss, trouble concentrating and thinking, and changes in personality and behavior, devastates patients, their families and loved ones.

6 Jun 2025

Integrating discoveries with translational science to transform Alzheimer's care

At the 12th annual Helen and Robert Appel Alzheimer's Disease Research Institute Symposium, scientists and clinicians shared their latest research which is advancing how Alzheimer's disease is diagnosed and treated.

4 Jun 2025

Household environments may affect the likelihood of children developing eczema

Household environments, including owning a dog, may affect the likelihood of children developing eczema, according to an analysis of almost 300,000 people from across Europe.

4 Jun 2025

TTF1 identified as key biomarker for advanced KRAS G12C-mutated non-small cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center have identified a new biomarker, TTF-1, that was predictive of survival outcomes for patients with advanced KRAS G12C-mutated non-small cell lung cancer (NSCLC), following treatment with the KRAS targeted therapy sotorasib.

30 May 2025

Blood test pinpoints early Alzheimer’s risk with high accuracy

Researchers evaluated a fully automated plasma biomarker panel to detect early amyloid-β accumulation in cognitively unimpaired adults at risk for Alzheimer’s disease. Plasma p-tau217/Aβ42 emerged as the most robust and accurate blood-based marker for identifying preclinical amyloid pathology.

26 May 2025

New blood test speeds up diagnosis of rare childhood diseases

A new, rapid testing method will greatly help the diagnosis of rare diseases in babies and children, according to research to be presented to the annual conference of the European Society of Human Genetics today (Monday).

25 May 2025

New AI blood test tracks pancreatic cancer treatment response

An artificial intelligence technique for detecting DNA fragments shed by tumors and circulating in a patient's blood, developed by Johns Hopkins Kimmel Cancer Center investigators, could help clinicians more quickly identify and determine if pancreatic cancer therapies are working.

22 May 2025

How innovation in dried blood spot testing is transforming neurological disease monitoring

In this interview, NewsMedical speaks with Quanterix about blood spot testing for neurological applications.

From Quanterix 21 May 2025

Study finds higher rates of pulmonary embolism in pediatric patients

Pulmonary embolism in children has been acknowledged to be an issue in clinical care but was thought to be rare.

20 May 2025

New blood test detects HPV-linked head and neck cancer with unmatched accuracy

A new liquid biopsy blood test could help detect cases of human papillomavirus (HPV)-associated head and neck cancers with significantly higher accuracy than currently used methods, including before patients develop symptoms, according to new Mass General Brigham research.

20 May 2025

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the commonest cancer in childhood and one that can be particularly difficult to treat in older patients, according to Cambridge scientists.

20 May 2025

Novel Alzheimer's therapy shows low risk of severe side effects

The Food and Drug Administration's approval in 2023 of lecanemab - a novel Alzheimer's therapy shown in clinical trials to modestly slow disease progression - was met with enthusiasm by many in the field as it represented the first medication of its kind able to influence the disease.

12 May 2025

Millions of women may be unaware of their risk for cardiovascular-kidney-metabolic disease

Millions of women may be unknowingly living with risk factors for heart, kidney and metabolic disease – interconnected conditions that together drive risk for cardiovascular disease, the leading cause of death among women, according to experts with the American Heart Association, a global force changing the future of health for all.

12 May 2025

Newly identified gene mutation causes severe form of Fanconi anemia

Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into adulthood only with bone marrow transplantation and regular cancer screening.

11 May 2025

Annual blood test could detect cancer earlier and save lives

A single blood test, designed to pick up chemical signals indicative of the presence of many different types of cancer, could potentially thwart progression to advanced disease while the malignancy is still at an early stage and amenable to treatment in up to half of cases, suggests a modelling study published in the open access journal BMJ Open.

8 May 2025

New predictive algorithms improve early detection of undiagnosed cancers

Two new advanced predictive algorithms use information about a person's health conditions and simple blood tests to accurately predict a patient's chances of having a currently undiagnosed cancer, including hard to diagnose liver and oral cancers.

7 May 2025