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Real-time Raman monitoring for pharmaceutical hot melt extrusion

Discover how real-time Raman monitoring enhances API control and quality during hot melt extrusion.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 10 Sep 2025

Experts review the evidence on coenzyme Q10 and cognitive decline

Researchers reviewed evidence on coenzyme Q10 (CoQ10) and cognition, finding strong biological support and positive results in animal models but mixed outcomes in human trials. Larger, high-quality studies are needed to clarify whether CoQ10 can protect against cognitive decline and neurodegenerative diseases.

9 Sep 2025

Unlocking the secrets of oral bacteria to fight tooth decay

If Wenjun Zhang has her way, no one will ever have to brush or floss again.

5 Sep 2025

Why metformin could protect the brain by rewiring mitochondria

Metformin boosts human oligodendrocyte differentiation and myelination across stem-cell, organoid, and chimera models. The study links these effects to mitochondrial metabolic shifts, supporting its potential as a therapy for multiple sclerosis.

1 Sep 2025

University of Vienna team develops method to measure molecular charges

An international research team led by the University of Vienna has succeeded in developing a new method to directly measure partial charges in molecules. The results, now published in Nature, provide new insights into molecular interactions and offer potential applications in drug development and materials science.

22 Aug 2025

Midkine found to prevent Alzheimer’s-related protein assemblies

Scientists at St. Jude Children's Research Hospital demonstrated for the first time that the protein midkine plays a preventative role against Alzheimer's disease.

21 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

How the Vutara VXL simplifies single-molecule imaging

Explore how the Bruker Vutara VXL advances single-molecule imaging across DNA, RNA, and proteins

From Bruker Nano Surfaces and Metrology 20 Aug 2025

Curcumin activates SIRT3 to protect bone structure in diabetic mice

In a new Scientific Reports study, curcumin protected bone-forming cells from high-glucose damage by activating the SIRT3/FoxO3a/NRF2 antioxidant pathway and restoring mitochondrial health. In diabetic mice, curcumin improved bone density and oxidative balance, highlighting its potential in osteoporosis prevention.

13 Aug 2025

Study: Lignin shows strong antiviral and antibacterial properties

Research from the Nanoscience Center of the University of Jyväskylä, Finland, has revealed that lignin, a polyphenol, important for plant structure, has antimicrobial activity against viruses and bacteria.

12 Aug 2025

Australian researchers uncover new target for next-generation malaria vaccines

Australian researchers have visualized a key protein complex in malaria parasites for the first time, uncovering a new target for next-generation vaccines that could help stop the disease from spreading.

6 Aug 2025

Study offers a promising new approach to stabilizing biomolecules

A new study from researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) reveals that extremely simple peptides can mimic a biological process that protects sensitive proteins from environmental stress.

5 Aug 2025

LptM protein revealed as essential to outer membrane stability in bacteria

Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria.

4 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

Johns Hopkins uncovers protein's unexpected role in brain signaling

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with genetically engineered mice.

4 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

Zinc from needle shields may contribute to syringe clogging

Employees of the technology transfer centre ANAXAM and researchers from the Paul Scherrer Institute PSI used the unique analytical methods available at PSI to look inside pre-filled syringes.

31 Jul 2025

Bacteria use amyloids as molecular armor against predators

Amyloids are perhaps best known as a key driver of Alzheimer's disease.

30 Jul 2025

Researchers map atomic structure of protein complex driving cilia movement

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

28 Jul 2025

Decoding DNA packing: Understanding nucleosomes' role in cellular efficiency

Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers-about a millionth of a milliliter. The cell manages this by winding the strings of DNA around protein spools. The protein-DNA complexes are called nucleosomes, and they ensure that DNA is safely stored.

28 Jul 2025