Hypersensitivity News and Research

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Hypersensitivity is an exaggerated response by the immune system to a drug or other substance.

Non-invasive test of brain function could predict treatment response in depressed teen girls

The risk of developing major depressive disorder (MDD) surges during adolescence-particularly for girls. Cognitive behavioral therapy (CBT) can be an effective treatment, but only about half of girls diagnosed with depression show significant improvement.

16 Sep 2020

Researchers discuss the role of chemical senses in disease and social interactions in humans, animals

Across 5 days in August (3rd-7th), scientists from around the world gathered virtually to present and discuss new information on the role of the chemical senses in disease, nutrition, and social interactions in humans and animals.

9 Sep 2020

Scientists identify genetic risk factors underlying penicillin allergy

Penicillin, a life-saving medicine, is the most common cause of drug allergy, with clinical manifestations ranging from temporary skin reactions to life-threatening systemic syndromes.

3 Sep 2020

Lysin-based antibacterial agent can help treat drug-resistant bacterial infections

The Centers for Disease Control and Prevention (CDC) has prioritized finding effective treatment of Methicillin-resistant Staphylococcus aureus (MRSA), one of the most common bacterial pathogens and the single most deadly drug-resistant bacteria in the United States.

3 Sep 2020

Study shows how genetics could improve safety and efficacy of drugs for COVID-19 treatment

Over the past few months, a number of drugs have been under investigation to treat COVID-19 without well-established safety or data to support these claims.

28 Aug 2020

Vaping-related lung injuries have suggestive patterns on CT scans

Injuries to the lungs from vaping have suggestive patterns on CT scans that could help physicians make accurate diagnoses and reduce unnecessary biopsies, according to a new study published in the journal Radiology: Cardiothoracic Imaging.

27 Aug 2020

Researchers develop vaccine for human herpesvirus 6B

A research group led by Professor MORI Yasuko (of the Division of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine) has revealed that the HHV-6B glycoprotein complex gH/gL/gQ1/gQ2 is an effective vaccine candidate for human herpesvirus 6B (HHV-6B).

20 Aug 2020

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

ETH Zurich scientists have developed an RNA molecule that can be used in bone marrow cells to correct genetic errors that affect protein production.

18 Aug 2020

FDA approves drug for treatment of neuromyelitis optica spectrum disorder

The U.S. Food and Drug Administration has approved Enspryng (satralizumab-mwge) for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in adults with a particular antibody - patients who are anti-aquaporin-4 or AQP4 antibody-positive.

17 Aug 2020

FDA approves opioid agonist for management of moderate to severe acute pain in adults

Today, the U.S. Food and Drug Administration approved Olinvyk (oliceridine), an opioid agonist for the management of moderate to severe acute pain in adults, where the pain is severe enough to require an intravenous opioid and for whom alternative treatments are inadequate.

9 Aug 2020

Neuroscientists map brain's sensory gatekeeper in unprecedented detail

Many people with autism experience sensory hypersensitivity, attention deficits, and sleep disruption. One brain region that has been implicated in these symptoms is the thalamic reticular nucleus (TRN), which is believed to act as a gatekeeper for sensory information flowing to the cortex.

22 Jul 2020

Eating black raspberries may reduce skin inflammation associated with allergies, study shows

Eating black raspberries might reduce inflammation associated with skin allergies, a new study indicates.

2 Jul 2020

Researchers investigate the effects of isolation in zebrafish

Over the past few months at least half of the world's population has been affected by some form of lockdown due to COVID-19, and many of us are experiencing the impact of social isolation.

10 Jun 2020

Using functional MRI to demonstrate neural suppression in autism

According to the National Autism Association, people with autism spectrum disorder (ASD) may experience sensory hypersensitivity.

29 May 2020

Frog brain discovery may pave the way for repairing birth defects in humans

A team of researchers from Tufts University, Universitat de Valencia, and Harvard University has discovered that the brains of developing frog embryos damaged by nicotine exposure can be repaired by using “ionoceuticals” that can help in the recovery of bioelectric patterns in the embryo.

28 May 2020

New animal model for COVID-19

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage the world, scientists are frantically searching for a vaccine or new drug that will effectively counter the lethal effects of the virus that leads to COVID-19 disease.

19 May 2020

Study: Gut microbiomes of astronauts become more diverse in space rather than less

We all carry around our own microbiome, a world of microorganisms that live on our skin and in our bodies, playing important roles in maintaining health as we interact with the rest of the world.

15 May 2020

ACR releases new guideline for management of gout

Today, the American College of Rheumatology released the 2020 Guideline for the Management of Gout.

11 May 2020

UMB and UMD fund cross-campus research projects

The University of Maryland, Baltimore (UMB) and the University of Maryland, College Park (UMD) are funding new cross-campus research projects as part of a new joint program that seeks to solve big health care challenges through joint research that draws on the institutions world leading expertise in medicine and artificial intelligence.

23 Apr 2020

Study reveals the neural basis of sensory hypersensitivity in people with autism

Many people with autism spectrum disorders are highly sensitive to light, noise, and other sensory input. A new study in mice reveals a neural circuit that appears to underlie this hypersensitivity, offering a possible strategy for developing new treatments.

2 Mar 2020