Immunization News and Research

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Lassa virus vaccine induces rapid protection in an animal model

Scientists have developed a novel Lassa vaccine using a recombinant measles virus and tested its protective efficacy against Lassa fever. A single vaccine dose has been found to induce a rapid and robust immune response in monkeys with pre-existing immunity against the measles virus.

14 Mar 2023

Vaccination protects lupus patients from contracting COVID-19

Researchers determine the risk of COVID-19 and possibility of severe sequelae in patients with systemic lupus erythematosus and the general population.

14 Mar 2023

Insufficient sleep results in decreased antibody response to vaccination

In reviewing data from previous studies, a team lead by researchers at the University of Chicago and the French National Institute of Health and Medical Research (Inserm) found that individuals who had fewer than six hours of sleep per night in the days surrounding vaccination had a blunted antibody response.

14 Mar 2023

How does SARS-CoV-2 interact with other pathogens?

In a recent study published in the PLOS Pathogens journal, researchers examine the present body of information regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interactions.

13 Mar 2023

Exploring COVID-19 immunization speed and timing in Africa

A new BMC Medicine study retrospectively analyzed the impact of COVID-19 vaccination timing and speed on the virus transmission in 27 African countries, based on a combined epidemiological and economic modeling approach. The authors aimed to inform future decisions about vaccine roll-out and investment.

10 Mar 2023

Montana considers new wave of legislation to loosen vaccination rules

When Deb Horning's youngest daughter was 5, she got her measles, mumps, and rubella shot like many other kindergartners. But unlike many other moms, Horning had to stay away from her daughter for a week after the shot.

10 Mar 2023

Investigating the impact of COVID-19 vaccinations in immunocompromised adult patients

In a recent study posted to the medRxiv* preprint server, researchers assessed the impact of third and fourth coronavirus disease 2019 (COVID-19) vaccination doses on immunity against COVID-19 among immunocompromised adult patients.

9 Mar 2023

Evaluating SARS-CoV-2 bivalent booster vaccine against severe COVID-19 outcomes

In a recent study posted to the medRxiv* preprint server, researchers assessed the effectiveness of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) bivalent booster vaccine against severe SARS-CoV-2 infection outcomes.

9 Mar 2023

Effectiveness of monovalent COVID-19 mRNA booster vaccination vs. two-dose primary series during Omicron variant circulation

Researchers estimated the immune protection conferred by monovalent-type COVID-19 mRNA booster doses vs. two-dose prime vaccination series during SARS-CoV-2 Omicron variant predominance in community settings.

7 Mar 2023

Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses

Researchers evaluate the response of pre-existing immunity to booster doses of mRNA COVID-19 vaccines.

6 Mar 2023

Novel predictors of severe respiratory syncytial virus infections among infants below the age of one

Researchers examined predictors for hospitalization due to respiratory syncytial virus (RSV) infections to develop a clinical model for guiding immunization and prophylactic treatment of one-year-old infants against RSV infections.

3 Mar 2023

Does the incidence of reported myocarditis or pericarditis after BNT162b2 vaccination vary by age, sex, and inter-dose interval among adolescents aged 12 to 17?

Researchers conducted a population-based cohort study among 12 to 17-year-old adolescents in Ontario, Canada, to estimate the incidence of myocarditis or pericarditis after BNT162b2 vaccination.

3 Mar 2023

New solutions to boost Africa’s vaccine production

The COVID-19 pandemic has highlighted the importance of vaccines in controlling infectious disease in sub-Saharan Africa and renewed interest in vaccine research and development across the continent.

28 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Study highlights COVID-19 vaccine safety among children

Researchers evaluate COVID-19 vaccine-associated serious adverse events following immunization among five- to 17-year-old children.

23 Feb 2023

Is the advantage conferred by the heterologous regimen conserved after a booster dose of mRNA-based COVID-19 vaccine?

Researchers compared the efficacy of a third COVID-19 vaccine dose and that of homologous and heterologous regimens.

23 Feb 2023

Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants

Researchers assessed the impact of a single-dose dendritic cell vaccine candidate on immune responses against SARS-CoV-2.

23 Feb 2023

CDC evaluation of the efficacy of monovalent mRNA vaccines in preventing symptomatic SARS-CoV-2 infection in 3 to 5-year-olds

The complete primary series monovalent mRNA vaccines protect children aged three to five against symptomatic infection for up to four months.

22 Feb 2023

CDC provides vaccine efficacy estimates of Pfizer and Moderna vaccines in kids ages 3-5

Vaccination coverage among infants and children varied according to age, race and ethnicity, jurisdiction, and rural and urban settings

22 Feb 2023

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas islets. This investigator-initiated clinical trial, published in Nature Communications, focused exclusively on children with recent onset T1D.

22 Feb 2023

Immunization News and Research

Lassa virus vaccine induces rapid protection in an animal model

Vaccination protects lupus patients from contracting COVID-19

Insufficient sleep results in decreased antibody response to vaccination

How does SARS-CoV-2 interact with other pathogens?

Exploring COVID-19 immunization speed and timing in Africa

Montana considers new wave of legislation to loosen vaccination rules

Investigating the impact of COVID-19 vaccinations in immunocompromised adult patients

Evaluating SARS-CoV-2 bivalent booster vaccine against severe COVID-19 outcomes

Effectiveness of monovalent COVID-19 mRNA booster vaccination vs. two-dose primary series during Omicron variant circulation

Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses

Novel predictors of severe respiratory syncytial virus infections among infants below the age of one

Does the incidence of reported myocarditis or pericarditis after BNT162b2 vaccination vary by age, sex, and inter-dose interval among adolescents aged 12 to 17?

New solutions to boost Africa’s vaccine production

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Study highlights COVID-19 vaccine safety among children

Is the advantage conferred by the heterologous regimen conserved after a booster dose of mRNA-based COVID-19 vaccine?

Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants

CDC evaluation of the efficacy of monovalent mRNA vaccines in preventing symptomatic SARS-CoV-2 infection in 3 to 5-year-olds

CDC provides vaccine efficacy estimates of Pfizer and Moderna vaccines in kids ages 3-5

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

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