Metabolome News and Research

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Researchers highlight role of micro-guests in pathologic processes

We host more microbiota than our own cells. These micro-guests produce metabolites that are only beginning to be appreciated as important factors in pathologic processes, from chronic inflammatory diseases to preterm birth.

1 Aug 2017

$Promising target may open door to new therapies for preventing bone fractures in diabetes patients$

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes.

7 Jul 2017

New study finds dramatic reorganization of the gut caused by weight loss surgery

Obesity, already a global epidemic, is on the rise. Over one-third of the U.S. population is currently afflicted, according to the Centers for Disease Control and the monetary costs alone are approaching $150 billion dollars annually.

26 May 2017

Decoding the Exposome Through Breath Biomarkers

The human exposome is probably best defined as “everything that is not the genome.” This is a bit tongue in cheek, but basically, the exposome is comprised of all of the chemicals in your body from the environment, food, consumer products, their metabolites, the endogenous “housekeeping” chemicals, the cellular wastes from energy production, as well as all of the messenger compounds and life supporting chemicals.

From Pittcon 24 Feb 2017

NMR and metabolic phenotyping

In this interview, Dr Harmut Schafer introduces the work being done at the Phenome Center in Birmingham, on metabolic phenotyping using NMR.

From Bruker BioSpin Group 31 Jan 2017

Metabolomics and NMR

Bruker has been involved in the Phenome Center network since its beginning. Several years ago, the whole visionary concept of a global phenome network was actually born with Professor Jeremy Nicholson and Bruker BioSpin has been part of it since the early stages.

From Bruker BioSpin Group 17 Jan 2017

Endometrial microbiota play vital role in determining reproductive outcome in women undergoing IVF

Endometrial microbiota (bacteria in the uterine cavity) play an important role in determining whether women are able to get pregnant via in vitro fertilization (IVF), according to a new study published in the American Journal of Obstetrics and Gynecology.

6 Dec 2016

New Baylor study aims to investigate antibiotic effect in children with ASD

Over the Thanksgiving holiday in 2012, John Rodakis, a father of a child with autism, observed his son's condition dramatically improve while taking a common antibiotic.

1 Dec 2016

ToMMo scientists identify genetic variants affecting enzymatic activities in healthy people

Scientists from Tohoku University's Tohoku Medical Megabank Organization have published research about genetic diversity and metabolome in Scientific Reports.

1 Sep 2016

UTHealth scientists discover powerful predictors of congestive heart failure

A team of scientists at The University of Texas Health Science Center at Houston and Baylor College of Medicine, led by Eric Boerwinkle, Ph.D., Richard Gibbs, Ph.D., and Bing Yu, Ph.D., have identified powerful predictors of congestive heart failure, a major cause of hospitalization and death in the United States.

31 Aug 2016

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

MetaboBASE personal libraryTM introduced by Bruker

At ASMS 2016, Bruker announces a new mass spectral library called Bruker MetaboBASE Personal LibraryTM, which contains high-resolution, accurate mass MS/MS spectra of over 13,000 metabolic compounds for the seamless identification of metabolites.

From Bruker Daltonics 7 Jun 2016

NASA releases new video that highlights Mark and Scott Kelly's metabolites

NASA's Human Research Program is releasing "Metabolomics: You Are What You Eat" video to highlight its Twins Study which uses omics to study Mark and Scott Kelly's metabolites.

28 May 2016

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Glyphosate, often sold under the brand name of Roundup, is the world's most widely used weed-killer. While Glyphosate has approval from regulatory bodies worldwide, there are growing concerns about its possible adverse health effects.

20 May 2016

High–performance, cost-effective NMR solutions for the pharmaceutical and chemical industries

At the 57th Experimental Nuclear Magnetic Resonance Conference (www.enc-conference.org), Bruker is showcasing several innovative drug discovery, drug development and process control solutions for small molecule NMR characterization in the chemical and pharmaceutical industries.

From Bruker BioSpin Group 11 Apr 2016

Stemina developing new screening method to diagnose autism

A University of Wisconsin-Madison spinoff is screening blood samples in an effort to develop a biologically based method to diagnose autism.

2 Mar 2016

New findings could help better understand neurodegenerative diseases

Researchers at the Luxembourg Centre for Systems Biomedicine (LCSB), of the University of Luxembourg, have, under Dr. Manuel Buttini, successfully measured metabolic profiles, or the metabolomes, of different brain regions, and their findings could help better understand neurodegenerative diseases.

18 May 2015

Metabolon announces launch of fourth-generation metabolomics platform

Metabolon, Inc., a leader in metabolomics-driven biomarker discovery, announced today the launch of DiscoveryHD4, the company's fourth-generation metabolomics platform.

4 Apr 2014

Human Urine Metabolome Study Envisions New Diagnostic Era

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6 Sep 2013

More than 3,000 chemicals or "metabolites" can be detected in urine, say researchers

Researchers at the University of Alberta announced today that they have determined the chemical composition of human urine. The study, which took more than seven years and involved a team of nearly 20 researchers, has revealed that more than 3,000 chemicals or "metabolites" can be detected in urine.