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AI-driven microscopy predicts and tracks protein aggregation in real time

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's.

24 Jul 2025

New 3D tissue model offers hope for scleroderma treatment

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, liver, and kidneys, as well as skin.

22 Jul 2025

Study reveals how aging alters liver function and structure

The aging liver undergoes dramatic changes in its functional organization and other key attributes, which may underpin its increasing susceptibility to disease, according to a study led by investigators at Weill Cornell Medicine.

17 Jul 2025

Hungry bacteria choose food over danger in the human gut

Bacteria that cause intestinal infections typically avoid a stinky chemical - one that can kill them at high enough concentrations - inside human intestines, but they may actually swim toward it when a hearty meal is the reward.

16 Jul 2025

New imaging technique reveals mitochondrial activity inside live animals

In this study, researcher developed a new imaging approach that combines two powerful techniques to solve this problem. First, a special type of microscope called a two-photon microscope is used, which can look deep into live tissues with minimal damage.

14 Jul 2025

More than 200 types of misfolded proteins could be associated with age-related cognitive decline

For decades, the story of Alzheimer's research has been dominated by a battle between A-beta and tau amyloids, both of which can kill neurons and impact the brain's ability to function.

11 Jul 2025

Energy waves on cancer cell surfaces linked to tumor growth and aggressiveness

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine say they have shed new light on the location and function of power-generating waves on the covering, or membrane, of these cells.

9 Jul 2025

Ireland's first and only BioBrillouin microscope installed at Trinity College Dublin

Trinity College Dublin now has Ireland's first and only BioBrillouin microscope, which will enable researchers to make giant strides in the fields of inflammation, cancer, developmental biology and biomedical materials, among others.

5 Jul 2025

Fluorescent drug helps surgeons see nerves clearly during complex procedures

When surgeons dissect tissue to remove a tumor or make a repair they must work cautiously, relying on electrophysical monitors and their own anatomical knowledge to avoid cutting nerves, which could complicate the patient's recovery.

4 Jul 2025

Chemist awarded NSF grant to study DNA nanoparticles for gene therapy

Case Western Reserve University chemist Divita Mathur was awarded a National Science Foundation (NSF) Faculty Early Career Development Program (CAREER) grant for her research in synthetic DNA nanoparticles, which have potential applications in gene therapy.

4 Jul 2025

Real time imaging reveals how visual experience rewires the brain

Scientists have long known that the brain's visual system isn't fully hardwired from the start-it becomes refined by what babies see-but the authors of a new MIT study still weren't prepared for the degree of rewiring they observed when they took a first-ever look at the process in mice as it happened in real-time.

4 Jul 2025

Older women face increased risk of HPV-related cervical cancer

Women aged 65 and above are still at heightened risk of cervical cancer caused by human papillomavirus (HPV), suggest the findings of a large observational study published in the open access journal Gynecology and Obstetrics Clinical Medicine.

2 Jul 2025

Leukemia-on-a-chip offers breakthrough in personalized cancer treatment

A team of researchers led by NYU Tandon School of Engineering's Weiqiang Chen has developed a miniature device that could transform how blood cancer treatments are tested and tailored for patients.

2 Jul 2025

PIEZO2 ion channel plays critical role in the formation of coronary vessels and the heart

The ion channel PIEZO2 doesn't just convey touch stimuli. It also plays a key role in the development of coronary vessels, a team led by Annette Hammes from the Max Delbrück Center reports in "Nature Cardiovascular Research."

27 Jun 2025

Scaling B-cell cloning workflows for antibody development

Explore the latest tools that boost speed and accuracy in B-cell cloning processes.

From Cellenion 24 Jun 2025

Capsule sponge test offers less invasive option for monitoring Barrett's esophagus

Endoscopies could be replaced by far less invasive capsule sponge tests for half of all patients with Barrett's esophagus, a known precursor to esophageal cancer, according to a new study from researchers at the University of Cambridge, Addenbrooke's Hospital and Queen Mary University of London.

23 Jun 2025

Pandorabactins help pathogenic bacteria compete for iron in the lungs

An interdisciplinary research team led by the Leibniz-HKI in Jena has discovered a new group of bioactive natural compounds in pathogenic bacteria of the genus Pandoraea: pandorabactins.

19 Jun 2025

Study: HIV is a flexible cellular hijacker

University of Michigan researchers have uncovered new details of the process that HIV uses to hijack cells’ transportation systems for its own survival.

19 Jun 2025

Machine learning boosts accuracy of point-of-care disease detection

What if people could detect cancer and other diseases with the same speed and ease of a pregnancy test or blood glucose meter? Researchers at the Carl R. Woese Institute for Genomic Biology are a step closer to realizing this goal by integrating machine learning-based analysis into point-of-care biosensing technologies.

17 Jun 2025