Nucleotides News and Research

RSS

Impact of truncated open reading frame 8 protein variants of SARS-CoV-2

A new study identified unique truncated open reading frame 8 proteins among SARS-CoV-2 sequences.

25 Mar 2022

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

A new study evaluated the N terminal domain of the SARS-CoV-2 nucleocapsid protein. It presented the targeted characteristics for selective ribonucleic acid identification by SARS-CoV-2 N in its 5'-genomic end.

24 Mar 2022

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

A recent study demonstrated that RNA interference could prophylactically protect against SARS-CoV-2.

24 Mar 2022

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

There is likely recombination of genome sequences between the SARS-CoV-2 Delta and Omicron variants in their spike (S) protein.

23 Mar 2022

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

A new study reported the development of colorimetric sensors for the detection of SARS-CoV-2 ribonucleic acid-dependent RNA polymerase, envelope, and spike genes.

21 Mar 2022

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

Researchers used molecular surveillance to identify cases of co-infection with SARS-CoV-2 variants of concern Delta and Omicron reported in Argentina during December 2021 and January 2022.

17 Mar 2022

New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

In a recent research paper currently available on bioRxiv* preprint server, scientists from the University of Oxford in the United Kingdom and the University of Auckland in New Zealand identified several structural specificities of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may serve as viable starting points for the development and optimization of viral inhibitors against coronavirus disease 2019 (COVID-19) and other future threats.

16 Mar 2022

A new view of SARS-CoV-2 genome structure

Researchers performed DMS mutational profiling with sequencing and DREEM clustering to determine the SARS-CoV-2 RNA secondary structure.

8 Mar 2022

Current and future perspectives of mRNA technology

New research reports on the current and future perspectives on messenger ribonucleic acid technology, the platform on which the first successful COVID-19 vaccine was based.

8 Mar 2022

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

Researchers from Columbia Engineering, Fiocruz's Center for Technological Development in Health and the Oswaldo Cruz Institute in Brazil, Memorial Sloan Kettering Cancer Center, and Rockefeller University recently reported that, by combining inhibitors of polymerases and exonucleases--enzymes that allow SARS-CoV-2 to reproduce--they were able to reduce SARS-CoV-2 replication 10 times more than when using just the polymerase inhibitors.

7 Mar 2022

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

In a new study, researchers used deep transcriptome analysis to examine the coding and non-coding transcriptional landscape of lung cells infected with SARS-CoV-2.

1 Mar 2022

A study on the evolution of avian coronavirus escape mutants in vitro

A recent study included an in vitro assessment of the effect of antibody titers and vaccine combinations on the emergence of escape mutants of AvCoV.

28 Feb 2022

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

In a review published in the International Journal of Molecular Sciences, researchers have been reviewing the use of siRNAs to target coronaviruses.

25 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Photoinactivating effect of visible light on viruses

The current literature study focused on visible light inactivation investigations of viruses.

23 Feb 2022

Circulating miR-155 may predict chances of survival in hospitalized COVID-19 patients

Scientists from Israel have recently estimated the levels of circulating microRNAs (miRNAs) in hospitalized coronavirus disease 2019 (COVID-19) patients with the aim of identifying prognostic biomarkers for disease severity. They have identified miR-155, an important regulatory molecule in the immune system, as a potential biomarker to predict COVID-19 severity and mortality.

22 Feb 2022

Novel platform can become a potential approach for personalized cancer treatments

Killing cancer cells without affecting surrounding normal cells is the most desirable approach for targeted cancer therapy. However, it cannot be easily achieved due to the similarities in the properties between normal and cancer cells.

22 Feb 2022

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

In a recent study published in the journal PLoS ONE, researchers investigated the effect of genetic variability based on accessory gene deletions on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and the clinical severity of coronavirus disease 2019 (COVID-19).

22 Feb 2022

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

In a recent study published in the journal PLoS ONE, researchers evaluated the temporal spread and geographic distribution of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) genomic variants.

21 Feb 2022

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

The multiplex detection approach outlined in this study has the potential to address the need to rapidly characterize the phenotype and clinical response to continually emerging SARS-CoV-2 variants as the COVID-19 pandemic continues.

16 Feb 2022

Nucleotides News and Research

Impact of truncated open reading frame 8 protein variants of SARS-CoV-2

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

A new view of SARS-CoV-2 genome structure

Current and future perspectives of mRNA technology

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

A study on the evolution of avian coronavirus escape mutants in vitro

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Photoinactivating effect of visible light on viruses

Circulating miR-155 may predict chances of survival in hospitalized COVID-19 patients

Novel platform can become a potential approach for personalized cancer treatments

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News