Organic chemistry News and Research

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New chemical method developed to introduce alkenes into simple hydrocarbon molecules

Chemists at Princeton have developed a new chemical method to introduce valuable alkenes into simple hydrocarbon molecules, a transformation known as dehydrogenation, which is found in important processes such as the biosynthesis of essential fatty acids in the body and the commercial production of detergents.

13 Dec 2015

New research project aims at improving companion diagnostics and therapy of tumor diseases

An international team from four EU countries plans to use an innovative concept to improve the use of companion diagnostics in disease and develop new approaches to therapy in the long term. The idea is to combine the use of nanomedicines and short half-life radionuclides for imaging purposes in the living organism.

22 Nov 2015

Unlocking the genes behind antibiotic resistance: an interview with Professor Romesberg

Bacteria are very, very diverse. This is why their susceptibility to different antibiotics can be very different. It also makes the tools they have to evolve resistance in many cases different.

30 Sep 2015

New technique could improve selectivity of cancer drugs, decrease unwanted side effects in future

A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life-threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.

11 Sep 2015

Johns Hopkins, IOCB Prague sign drug discovery research agreement

The Johns Hopkins Drug Discovery (JHDD) program, created with the mission of identifying novel drug targets arising from Johns Hopkins faculty research and translating them into new therapeutics, and the Institute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences (IOCB Prague) have entered into a five-year drug discovery research agreement to develop small-molecule and peptide drugs for a range of therapeutic areas including neurological diseases, cancer and gastrointestinal disorders.

9 Jul 2015

Hartmuth Kolb named recipient of 2015 Alzheimer Award

The Journal of Alzheimer's Disease is proud to announce that Hartmuth Kolb, PhD, Head of Neuroscience Biomarkers, Johnson & Johnson, San Diego, CA, has been chosen as the recipient of the 2015 Alzheimer Award presented by the Journal of Alzheimer's Disease in recognition of his outstanding work on the importance and imaging of neurofibrillary tangles (NFTs) and Alzheimer's disease (AD).

26 Jun 2015

From the scent of geranium to cough medicine; A self-assembling catalyst helps to construct complex biological scaffolds

With great elegance nature builds up complex structures from simple building blocks. A central class of compounds are terpenes. More than 8000 terpenes and about 30,000 of the related terpenoids are currently known. They are the key substances for many biological and pharmaceutical functions.

18 Feb 2015

AMRI optimizes global operations to improve continuous supply chain across its businesses

AMRI today announced that it has implemented several changes to further optimize global business operations in order to enhance continuity from early development through to commercial supply and accelerate the company's global growth objectives.

12 Feb 2015

Synthetic compound shows antibiotic action against MRSA

Microbiologists and chemists at the University of South Florida have developed and patented a synthetic compound that has shown antibiotic action against methicillin resistant Staphylococcus aureus, also known as MRSA, which can cause many serious infections and deaths.

30 Jan 2015

Eight researchers to receive 2015 Leibniz Prize

The new recipients of Germany's most prestigious research funding prize have been announced. In Bonn today, the Joint Committee of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) decided to award the 2015 Leibniz Prize to eight researchers.

18 Dec 2014

European scientists develop, test drug that could reduce harmful side-effects of 'binge drinking'

A drug that could reduce the harmful side-effects of 'binge drinking', especially by teenagers, has been successfully developed and tested by a team of European scientists, including the University of Huddersfield's Professor Mike Page and Dr Karl Hemming. There is also the potential for new ways to treat Alzheimer's and other neurological diseases that damage the brain.

27 Nov 2014

GW now accepts applications to Post-Baccalaureate Pre-Medicine Certificate Program

The George Washington University School of Medicine and Health Sciences is now accepting applications to the Post-Baccalaureate Pre-Medicine Certificate Program for the summer 2015 term.

9 Oct 2014

TSRI scientists devise new vancomycin-based antibiotic to rout resistant bacteria

Scientists at The Scripps Research Institute have devised a new antibiotic based on vancomycin that is powerfully effective against vancomycin-resistant strains of MRSA and other disease-causing bacteria.

18 Sep 2014

Advion introduces high performance liquid chromatography to complement its CMS

Advion, Inc., a leading systems and consumables developer for the life sciences industry, introduces an affordable high performance liquid chromatography system to complement its line of expression compact mass spectrometers (CMS). Introduced in 2012, the CMS has been met with glowing reviews from the global synthetic organic chemistry market. With hundreds of CMS purchased and installed, this latest introduction offers a complete solution for those needing separation capabilities at an affordable price.

From Advion 7 Aug 2014

Engineers create truly portable device for nuclear magnetic resonance spectroscopy

A team of engineers at the Harvard School of Engineering and Applied Sciences (SEAS), Schlumberger-Doll Research Center in Cambridge, Mass., and the University of Texas, Austin, have created a truly portable device for nuclear magnetic resonance (NMR) spectroscopy.

5 Aug 2014

Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

The natural DNA bases that form the letters of DNA are usually referred to as G, C, A, and T. Those are only the first letters of the chemical names. They’re often called nucleotides by their scientific name and all of them have in common a phosphate part, a sugar part and a nucleobase part.

21 Jul 2014

Research shows promise to speed up drug discovery for deadly diseases

Antibiotic resistance is depleting our arsenal against deadly diseases and infections, such as tuberculosis and Staph infections, but recent research shows promise to speed up the drug discovery process.

16 Jul 2014

Scientists develop new molecule for monitoring drug concentration

Monitoring the drug concentration in patients is critical for effective treatment, especially in cases of cancer, heart disease, epilepsy and immunosuppression after organ transplants.

9 Jun 2014

Chemist’s work could impact treatment of cancer and malaria

A University of Houston (UH) chemist hopes his work will one day impact the treatment of such diseases as cancer and malaria by better understanding how molecules react and how atoms come together to form bonds.

6 Jun 2014

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

We already understand the many steps involved in blood clotting in great mechanistic detail. The process of blood vessels closing off in response to injury is necessary for preserving life, but blood platelets that are over-active, or activated inappropriately because of unstable plaque, can lead to heart attacks and strokes.

3 Jun 2014