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New insights into glioblastoma resistance to temozolomide

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used as the front-line medicine in its treatment.

19 Dec 2024

Scientists detect rare H5N1 avian flu strain in Australian child after travel to India

A 2.5-year-old returning to Australia from India was infected with a reassortant H5N1 virus, revealing genetic mixing between avian influenza clades and gaps in South Asian surveillance.

18 Dec 2024

Gut microbiome during acute infection predicts risk of long COVID

The study identifies gut microbiome signatures during acute SARS-CoV-2 infection as predictors of long COVID, enhancing understanding of symptom variability.

16 Dec 2024

Study reveals evidence of 22 viruses in human semen post-infection

This study uncovers the persistence of 22 viruses in human semen, emphasizing the need for updated public health strategies and insights into fertility impacts.

16 Dec 2024

Lipid imbalances hold the key to chronic inflammation in colon cancer

Scientists uncover how disrupted lipid metabolism fuels chronic inflammation in colorectal cancer, offering insights into new therapeutic strategies targeting pro-inflammatory and pro-resolving lipid imbalances.

12 Dec 2024

Virus causes 20 million infections annually as study uncovers hidden drivers of its evolution

Researchers describe the evolutionary origins of hepatitis E virus in rodents.

12 Dec 2024

Gene therapy to prevent stillbirth and premature delivery developed

Researchers investigate the effectiveness of placental nano-based insulin-like 1 growth factor gene therapy to correct fetal growth restriction.

12 Dec 2024

Post-COVID health risks: Obesity fuels sequelae, smoking hits memory

Obesity significantly increases the risk of post-COVID-19 long-term sequelae, while smoking is primarily linked to memory disorders but does not raise the risk of long COVID symptoms or hospitalization.

9 Dec 2024

SARS-CoV-2 spike protein found lingering in brain regions

Researchers find that SARS-CoV-2 spike protein persists in the skull-meninges-brain axis, driving neuroinflammation, neurodegeneration, and heightened vulnerability to brain injuries.

3 Dec 2024

Nanozyme breakthrough offers new hope for viral pneumonia treatment

A recent study in Nature Materials introduces an inhalable nanozyme treatment for viral pneumonia, showing promising results in reducing inflammation and viral load in various mouse models. The nanozyme, CeTA-K1tkP, demonstrates broad-spectrum effects and biocompatibility, offering a potential new approach to treating pneumonia and other inflammatory conditions.

3 Dec 2024

New study sheds light on the molecular basis of gene expression

An international research collaboration has shed new light on the molecular basis of gene expression, the fundamental biological process that underpins how all organisms use their genetic information.

2 Dec 2024

Spatial transcriptomics uncovers new treatment paths for triple-negative breast cancer

Study uses spatial transcriptomics to map intratumoral heterogeneity and microenvironmental dynamics in triple-negative breast cancer (TNBC). The findings identify nine spatial archetypes and gene signatures linked to immunotherapy response and patient outcomes.

2 Dec 2024