Preclinical News and Research

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Harvard University hosts the world's largest conference dedicated to longevity biotechnology

The 13th Aging Research & Drug Discovery (ARDD) Meeting, the world's largest conference dedicated to longevity biotechnology, will take place from October 1-3, 2026, at the David Rubenstein Treehouse at Harvard University.

11 Jul 2026

Machine learning redefines precision cancer therapy using smart radiopharmaceuticals

JMIR Publications released a feature News and Perspectives story on technological advances in oncology.

11 Jul 2026

New generation approaches revive BET protein inhibitors in solid tumors

BET proteins, especially BRD4, drive oncogenic transcription in solid tumours. First‑generation inhibitors (JQ1, molibresib, birabresib) showed preclinical promise but failed clinically due to modest efficacy, dose‑limiting thrombocytopenia, and resistance (isoform switching, compensatory PI3K/AKT/WNT signalling).

11 Jul 2026

New stem cell therapy offers hope for chronic spinal injury

New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting highlights a significant step toward developing a stem cell-based treatment for chronic spinal cord injury (SCI), a condition for which no effective restorative therapy currently exists.

11 Jul 2026

Transplanted neural progenitor cells survive one year in patients with retinitis pigmentosa

New, previously unpublished clinical data was presented today at ISSCR 2026 demonstrating that transplanted human neural progenitor cells survived for at least one year following subretinal transplantation in patients with retinitis pigmentosa (RP), while maintaining a favorable safety profile.

9 Jul 2026

Multifloral honey may protect skin cells from UV damage and premature aging

Ongoing research reveals that multifloral honey is a promising candidate for protecting human skin cells from premature ageing and cell damage caused by UV radiation, with the potential for developing future clinical and cosmetic applications.

9 Jul 2026

Stem cell study uncovers molecular pathway for enamel regeneration

Tooth enamel is the hardest substance in the human body, yet once damaged, it cannot regenerate naturally.

9 Jul 2026

First clinical trial evaluates stem cell therapy for Huntington's disease

An update on the first clinical trial evaluating a pluripotent stem cell-derived neural stem cell therapy for Huntington's disease was presented today at the ISSCR 2026 Annual Meeting.

9 Jul 2026

Experimental compound BA-101 overcomes chemotherapy resistance in glioblastoma

Scientists have identified a promising new strategy to tackle one of the biggest obstacles in treating glioblastoma, one of the most aggressive form of brain cancer: resistance to chemotherapy.

9 Jul 2026

Spear Bio to unveil novel Alzheimer’s disease immunoassays and fully automated instrument platform at AAIC 2026

Spear Bio, an innovator in ultrasensitive protein biomarker detection, today announced plans to unveil new SPEAR immunoassay and instrument innovations at the Alzheimer’s Association International Conference® 2026, taking place July 12–15 in London, UK.

From Spear Bio 9 Jul 2026

Study identifies new target for Parkinson's disease neuroprotection

Parkinson's disease (PD) is the second most common form of neurodegenerative disease and afflicts more than ten million people worldwide. While current therapies address disease symptoms, they do not prevent the underlying neurodegeneration that drives the disease.

8 Jul 2026

Cosmetic microneedles deliver actives where creams struggle

This review shows how microneedle-based cosmetic systems bypass the stratum corneum to deliver poorly penetrating actives, including peptides, retinoids, vitamins, niacinamide, hyaluronic acid, and hair-growth compounds, into viable skin layers.

8 Jul 2026

Weill Cornell Medicine receives federal grant to study new gene therapy for Alzheimer's disease

The National Institute on Aging of the National Institutes of Health has awarded a five-year grant initially worth $8.37 million for Weill Cornell Medicine researchers to study a new gene therapy for Alzheimer's disease in people who have a high genetic risk of developing the condition.

8 Jul 2026

Novel strategy can make stem cell transplants safer

Stem cell transplantation (also called bone marrow transplantation) and gene therapy are among the most powerful curative approaches for blood diseases such as sickle cell disease, b-thalassemia, immune deficiencies, and some blood cancers.

8 Jul 2026

Teleoperated humanoid robots used to complete two surgeries during preclinical trial

For the first time, two teleoperated humanoid robots have been used to complete two surgeries during a preclinical trial, researchers report in the July 8 issue of the journal Nature.

8 Jul 2026

New review shows why antidepressants often fail in Alzheimer’s and Parkinson’s depression

A Molecular Psychiatry review shows that depression in Alzheimer’s and Parkinson’s disease may reflect disease-specific molecular, neurotransmitter, inflammatory, and circuit-level disruptions rather than standard depression biology alone. It argues that broad antidepressants often show limited efficacy in these patients and that future trials should use biomarkers, neuroimaging, and symptom profiling to guide targeted treatments.

7 Jul 2026

Study reveals why patients with rare leukemia develop resistance to tagraxofusp

Researchers at The University of Texas MD Anderson Cancer Center have identified why some patients with a rare type of leukemia, called blastic plasmacytoid dendritic cell neoplasm (BPDCN), eventually develop resistance to tagraxofusp, the first Food and Drug Administration-approved treatment for this disease.

7 Jul 2026

Preclinical News and Research

Harvard University hosts the world's largest conference dedicated to longevity biotechnology

Machine learning redefines precision cancer therapy using smart radiopharmaceuticals

New generation approaches revive BET protein inhibitors in solid tumors

New stem cell therapy offers hope for chronic spinal injury

Transplanted neural progenitor cells survive one year in patients with retinitis pigmentosa

Multifloral honey may protect skin cells from UV damage and premature aging

Stem cell study uncovers molecular pathway for enamel regeneration

First clinical trial evaluates stem cell therapy for Huntington's disease

Experimental compound BA-101 overcomes chemotherapy resistance in glioblastoma

Spear Bio to unveil novel Alzheimer’s disease immunoassays and fully automated instrument platform at AAIC 2026

Study identifies new target for Parkinson's disease neuroprotection

Cosmetic microneedles deliver actives where creams struggle

Weill Cornell Medicine receives federal grant to study new gene therapy for Alzheimer's disease

Novel strategy can make stem cell transplants safer

Teleoperated humanoid robots used to complete two surgeries during preclinical trial

New review shows why antidepressants often fail in Alzheimer’s and Parkinson’s depression

Study reveals why patients with rare leukemia develop resistance to tagraxofusp

Adaptor proteins regulate macrophage behavior to control cancer growth

New nonhormonal therapy shows promise for treating Genitourinary Syndrome of Menopause

Study identifies promising drug target to prevent neurodegenerative conditions

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