Respiratory Illness News and Research

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How SARS-CoV-2 enters the central nervous system

The central nervous system (CNS) is highly protected in the human body. Yet, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades the CNS, causing profound clinical complications. How is the CNS involved in a respiratory virus infection?

15 Feb 2021

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

Researchers at Icahn School of Medicine at Mount Sinai in New York have provided evidence suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – was infecting people in New York City (NYC) at least one month before the first case was officially documented in the city.

14 Feb 2021

Study offers new protocols for high-quality SARS-CoV-2 genomic sequencing

Researchers at the Southern Illinois University, U.S.A. have presented a comprehensive and well-validated set of working protocols for sequencing high-quality SARS-CoV-2 genomes in high throughput from patient samples.

12 Feb 2021

Lessons learnt from the annual influenza season

Australian researchers have come up with two key recommendations from studies of the annual influenza season - one highlighting the benefits of antivirals in reducing repeat hospitalisation, and the other to watch for underlying cardiovascular disease.

12 Feb 2021

History of vaccines offers guidance on COVID-19 prevention in pregnant women

Pregnant women, who are at increased risk of preterm birth or pregnancy loss if they develop a severe case of COVID-19, need the best possible guidance on whether they should receive a COVID-19 vaccine, according to an article by two UT Southwestern obstetricians published today in JAMA.

8 Feb 2021

Natural reinfection with respiratory syncytial virus varies based on antibody response

Researchers at Baylor College of Medicine found that while most individuals responded to respiratory syncytial virus (RSV) natural reinfection with a typical sustained antibody response associated with protection, a few individuals surprisingly responded atypically, not being able to sustain the antibody response, which declined to levels that made the individuals susceptible to RSV reinfection.

5 Feb 2021

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Researchers have shown that prescribing vitamin D supplementation to COVID-19 patients seems to decrease the mortality rate, the severity of the disease, and serum levels of inflammatory markers.

6 Jan 2021

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

In a recent bioRxiv* preprint paper, researchers from Germany analyzed aqueous licorice root extract for its neutralizing activity against SARS-CoV-2 in vitro. They identified glycyrrhizin, the primary active ingredient in the root, and revealed the underlying mechanism of viral neutralization.

5 Jan 2021

One-third of COVID-19 survivors manifest neurological problems

In a longitudinal study recently published on the preprint server medRxiv*, Andrea Pilotto et al. find that one-third of COVID-19 infection survivors have long-term neurological manifestations after hospitalization.

5 Jan 2021

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers from the Washington University School of Medicine, United States of America, recently demonstrated that the SARS-CoV-2 surface proteins alone triggered innate cell activity and the interferon signaling pathway.

17 Dec 2020

Neanderthal gene variant increases risk of severe COVID-19

Researchers in Germany have conducted a study showing that between 2 and 8% of people in Eurasia carry a genetic variant inherited from Neanderthals that significantly increases the risk of becoming critically ill with coronavirus disease 2019 (COVID-19).

15 Dec 2020

Neutrophils may play a key role in COVID-19-related thrombosis

A team of researchers in Italy have published a study suggesting that rather than platelets, neutrophils could be playing the lead role in thrombotic complications associated with COVID-19.

9 Dec 2020

People with vitamin D deficiency at higher risk of severe COVID-19, says study

A new study has revealed that vitamin D deficient patients are more likely to experience severe COVID-19.

4 Dec 2020

Researchers tie smoking to higher COVID-19 mortality in lower-middle-income countries

A team of researchers from the Epidemiology Department, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia, has found no correlations between adult male and female smoking prevalence with COVID-19 mortality across countries. In lower-middle-income countries, however, there is a link between adult male smoking prevalence with COVID-19-related death.

4 Dec 2020

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

The COVID-19 pandemic has led to millions of deaths across the globe. The causative agent of this disease is the novel coronavirus, SARS-CoV-2.

3 Dec 2020

SARS-CoV-2 versus Zika: Comparing and contrasting the flow of research

An interesting study published on the preprint server medRxiv in November 2020, dealing not with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is the cause of the COVID-19 pandemic, but with the publications that have appeared as a consequence of the outbreak, comparing them with the similar trove of publications that followed the Zika virus outbreak in 2016.

25 Nov 2020

FDA expands approved indication for influenza treatment to include post-exposure prevention

Today, the U.S. Food and Drug Administration expanded the approved indication for Xofluza (baloxavir marboxil) to include post-exposure prevention of influenza (flu) for patients 12 years of age and older after contact with an individual who has the flu.

23 Nov 2020

How COVID-19 compares to other respiratory illnesses

A team of scientists from Israel and the United States has compared the disease presentation and progression between in-hospital patients with coronavirus disease 2019 (COVID-19) and other respiratory illnesses such as influenza.

23 Nov 2020

Parents complain that pediatricians, wary of COVID, shift sick kids to urgent care

A mom of eight boys, Kim Gudgeon was at her wits' end when she called her family doctor in suburban Chicago to schedule a sick visit for increasingly fussy, 1-year-old Bryce.

23 Nov 2020

Researchers develop survey to understand factors that influence vaping

Before the COVID-19 pandemic, information about the dangers of vaping was emerging. To investigate the potentially serious health and respiratory implications of vaping, Mayo Clinic researchers wanted to better understand the factors influencing vaping in the community.

23 Nov 2020

Respiratory Illness News and Research

How SARS-CoV-2 enters the central nervous system

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

Study offers new protocols for high-quality SARS-CoV-2 genomic sequencing

Lessons learnt from the annual influenza season

History of vaccines offers guidance on COVID-19 prevention in pregnant women

Natural reinfection with respiratory syncytial virus varies based on antibody response

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

One-third of COVID-19 survivors manifest neurological problems

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Neanderthal gene variant increases risk of severe COVID-19

Neutrophils may play a key role in COVID-19-related thrombosis

People with vitamin D deficiency at higher risk of severe COVID-19, says study

Researchers tie smoking to higher COVID-19 mortality in lower-middle-income countries

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

SARS-CoV-2 versus Zika: Comparing and contrasting the flow of research

FDA expands approved indication for influenza treatment to include post-exposure prevention

How COVID-19 compares to other respiratory illnesses

Parents complain that pediatricians, wary of COVID, shift sick kids to urgent care

Researchers develop survey to understand factors that influence vaping

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