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Finerenone: A promising therapeutic option for cardiovascular diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Mineralocorticoid receptor antagonists (MRA) have significant therapeutic effects on heart failure, hypertension, chronic kidney disease and primary aldosteronism.

11 Oct 2023

Is night shift work rewiring our appetite and driving weight gain?

Bristol University scientists reveal that night shift work disrupts the body's circadian rhythm, altering appetite-regulating hormones and leading to weight gain. The study, providing insights into metabolic health, may aid in developing treatments for eating disorders and obesity.

10 Oct 2023

How vitamin D and genetics shape early brain development

The study examined how vitamin D levels and vitamin D binding protein genotypes in both pregnant mothers and their children aged 3-5, impact early childhood neurodevelopment. Findings suggest that higher vitamin D concentrations in children were associated with better neurodevelopmental scores, with additional influences from sociodemographic factors and certain genetic variations.

4 Oct 2023

Genetic markers could help identify people at risk for metabolic dysfunction-associated steatotic liver disease

An astounding 30% of Americans currently have metabolic dysfunction-associated steatotic liver disease, or MASLD, which is formerly known as nonalcoholic fatty liver disease, or NAFLD.

27 Sep 2023

Long COVID patients exhibit different immune and hormonal responses to the virus, study shows

People who have experienced brain fog, confusion, pain, and extreme fatigue for months or longer after being infected with the COVID-19 virus exhibit different immune and hormonal responses to the virus than those not diagnosed with long COVID, according to a new study by researchers at Yale School of Medicine and Icahn School of Medicine at Mount Sinai.

25 Sep 2023

When you think about your health, don’t forget your eyes

I vividly remember that late Friday afternoon when my eye pressure spiked and I staggered on foot to my ophthalmologist's office as the rapidly thickening fog in my field of vision shrouded passing cars and traffic lights.

22 Sep 2023

Transforming postpartum depression treatment with neurosteroids

A new study in Neuropsychopharmacology delves into the mechanisms of action of brexanolone, the first FDA-approved, rapid-acting antidepressant specifically for postpartum depression (PPD). The research highlights brexanolone's potential anti-inflammatory effects and its impact on GABAA receptors, offering insights into its efficacy and suggesting avenues for further study.

19 Sep 2023

Urban living linked to increased risk of respiratory infections in young children

Young children growing up in towns and cities suffer from more respiratory infections than those who grow up in the countryside, according to research presented at the European Respiratory Society International Congress in Milan, Italy.

11 Sep 2023

COVID-19 hits American Indian and Alaska Native populations hardest, new study reveals

A recent study at the University of New Mexico Hospital highlights that American Indian and Alaska Native populations face disproportionate severity and mortality rates from COVID-19. The research points to the urgent need for targeted interventions and resources to address these health disparities.

5 Sep 2023

New oral agent shows promise in treatment of relapsed multiple myeloma

A new agent that subverts myeloma cells from within while also subjecting them to an immune system attack produced impressive responses in combination with dexamethasone in patients with multiple myeloma that had relapsed and stopped responding to all currently available therapies, a clinical trial conducted by researchers at Dana-Farber Cancer Institute and around the world has found.

30 Aug 2023

How have inflammatory bowel disease treatments changed after the introduction of biologics?

Researchers compared changes in inflammatory bowel disease treatment strategies before and after the introduction of biologics in Japan.

24 Aug 2023

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Researchers described the preclinical profile of JT002, a novel and orally bioavailable small molecule inhibitor of the NLRP3 inflammasome.

24 Aug 2023

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Researchers investigated whether anti‑interleukin 6 monoclonal antibodies were related to heterogenous treatment effects between male and female COVID-19 patients.

24 Aug 2023

A computational model identifies metabolites associated with Parkinson's disease

Researchers identify significant metabolites involved in the development and progression of Parkinson’s disease.

15 Aug 2023

The role of estrogen in osteoarthritis and lower back pain

Researchers review existing evidence on the association between estrogen, osteoarthritis, and lower back pain.

10 Aug 2023

Penn State researchers develop new method for creating cyclopropanes

Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and require highly reactive - potentially explosive - ingredients. Now, a team of researchers from Penn State has identified and demonstrated a safe, efficient and practical way to create cyclopropanes on a wide variety of molecules using a previously undescribed chemical process.

4 Aug 2023

Experts call for caution when using antenatal corticosteroids

Two new studies published by The BMJ today examine the potential health risks for infants of giving steroid drugs to women who are at risk of giving birth early.

2 Aug 2023

Cadmium exposure disrupts placental hormones, harming fetal development

As with many toxins, exposure to the toxic metal cadmium during pregnancy can adversely impact fetal development.

28 Jul 2023

New technology could revolutionize treatment for age-related macular degeneration

Scientists have found a way to use nanotechnology to create a 3D 'scaffold' to grow cells from the retina –paving the way for potential new ways of treating a common cause of blindness.

28 Jul 2023

Muscle-building supplement may help protect memory and prevent Alzheimer's disease

The secret to protecting your memory may be a staple of a bodybuilder's diet. RUSH researchers recently discovered that a muscle-building supplement called beta-hydroxy beta-methylbutyrate, also called HMB, may help protect memory, reduce plaques and ultimately help prevent the progression of Alzheimer's disease.

21 Jul 2023

Steroid News and Research

Finerenone: A promising therapeutic option for cardiovascular diseases

Is night shift work rewiring our appetite and driving weight gain?

How vitamin D and genetics shape early brain development

Genetic markers could help identify people at risk for metabolic dysfunction-associated steatotic liver disease

Long COVID patients exhibit different immune and hormonal responses to the virus, study shows

When you think about your health, don’t forget your eyes

Transforming postpartum depression treatment with neurosteroids

Urban living linked to increased risk of respiratory infections in young children

COVID-19 hits American Indian and Alaska Native populations hardest, new study reveals

New oral agent shows promise in treatment of relapsed multiple myeloma

How have inflammatory bowel disease treatments changed after the introduction of biologics?

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

A computational model identifies metabolites associated with Parkinson's disease

The role of estrogen in osteoarthritis and lower back pain

Penn State researchers develop new method for creating cyclopropanes

Experts call for caution when using antenatal corticosteroids

Cadmium exposure disrupts placental hormones, harming fetal development

New technology could revolutionize treatment for age-related macular degeneration

Muscle-building supplement may help protect memory and prevent Alzheimer's disease

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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