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Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

Why are lithium coin batteries so dangerous to children?

News-Medical speaks to Dr. Tanya Altmann about her latest partnership with Duracell that is encouraging people to learn about lithium coin battery safety.

9 Nov 2021

Researchers identify new symptoms associated with pancreatic cancer

Researchers have identified a series of symptoms associated with pancreatic cancer, including two previously unrecognized symptoms – feeling thirsty and having dark urine – in a study presented today (Monday) at the NCRI Festival.

8 Nov 2021

Researchers explore whether salivary glands infected with SARS-CoV-2 can diminish long-term immunity

University of Utah Health scientists are leading an effort to determine if salivary glands infected with the virus that causes COVID-19 could diminish a person’s long-term immunity to the disease after being immunized or after recovering from the illness.

30 Oct 2021

New treatment for HPV-associated oropharynx cancer leads to excellent disease control, less side effects

Mayo Clinic researchers have found that a new, shorter treatment for patients with HPV-associated oropharynx cancer leads to excellent disease control and fewer side effects, compared to standard treatment.

26 Oct 2021

New data reveals safety, efficacy of nusinersen drug delivery method for SMA patients with advanced disease

A recently published paper details the safety and efficacy of nusinersen administration via a subcutaneous intrathecal catheter system (SIC) for SMA patients with advanced disease.

25 Oct 2021

Research uncovers a new human sensory ability to detect sugars in the mouth

Most everyone understands that a major role of our sense of taste is to inform us when sugar is present in foods and beverages by eliciting sweetness on our tongues. A study led by the Monell Chemical Senses Center, published this month in PLOS ONE, identifies a new human sensory ability to detect sugars in the mouth with a molecular calorie detector, of sorts.

20 Oct 2021

Study: Six out of ten patients with “red flag” cancer symptoms not referred for urgent investigation

Six out of ten patients who show common "alarm" symptoms for cancer are not referred for urgent investigation, a largescale new study has revealed.

5 Oct 2021

NYU Langone Health broadens access to high-quality primary and specialty care

NYU Langone Health continues to broaden access to high-quality primary and specialty care with recent expansions in Long Island, Queens, Manhattan, and Brooklyn.

5 Oct 2021

California’s reboot of troubled Medi-Cal puts pressure on health plans

When Denise Williams' baby boy was 2 months old, she became alarmed by a rattling sound in his lungs and took him to the emergency room. While undergoing treatment, he spiraled into a disabling neurological disorder.

21 Sep 2021

Does genetics affect eating behaviors?

A new study adopted a biological approach to assess if food-related behaviors and food involvement have a genetic explanation.

8 Sep 2021

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Octapharma USA today announced the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) has awarded seven years of marketing exclusivity for Octagam® 10% [Immune Globulin Intravenous (Human)], the first and only intravenous immunoglobulin (IVIg) to be indicated for the treatment of adult dermatomyositis (DM).

31 Aug 2021

Aston University secures KTP project to assist Catalent in developing orally disintegrating tablets

Aston University researchers based in the College of Health and Life Sciences have been awarded a Knowledge Transfer Partnership (KTP) project by Innovate UK, to bring its academic and scientific expertise to assist Catalent in the development of its Zydis® technology, the leading orally disintegrating tablet (ODT).

27 Aug 2021

Researchers identify a cluster of small molecules that contribute to coffee's mouthfeel

Coffee drinkers intuitively recognize the pleasure of swallowing a smooth, rich brew versus a watery one.

24 Aug 2021

Patient's case report reveals link between Bell’s palsy and Pfizer-BioNTech vaccine

The case of a patient who experienced two facial palsies – one after the first and another after the second dose of the Pfizer-BioNTech COVID-19 vaccine – strongly suggests that Bell’s palsy (facial nerve palsy of unknown cause) is linked to the Pfizer-BioNTech vaccine, doctors write in the journal BMJ Case Reports.

19 Jul 2021

Study may lead to electrical stimulation implants that restore intraoral functions

Even the mundane act of swallowing requires a well-coordinated dance of more than 30 muscles of the mouth. The loss of function of even one of these, due to disease or injury, can be extremely debilitating. For these people, nerve stimulation offers a ray of hope to regain some of their lost oral function.

1 Jul 2021

Study investigates difficulty swallowing in critically ill COVID-19 patients

Researchers from Clinica Luganese Moncucco and Bellinzona Regional Hospital in Switzerland investigated the prevalence of swelling disorders in severely ill COVID-19 patients and reported their results in a paper posted to the medRxiv* preprint server.

25 Jun 2021

Researchers describe a new science-based intervention for hiccups

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) and colleagues worldwide describe a new science-based intervention for hiccups in a research letter published June 18 in the journal JAMA Network Open.

21 Jun 2021

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Diverse messenger RNAs are produced in cells by “alternative splicing.” The Leducq Foundation is now supporting a transatlantic network dedicated to investigating this process in heart muscle cells and how changes in this process contribute to disease. Professor Michael Gotthardt of the MDC and Professor Leslie Leinwand of the University of Colorado Boulder are coordinating the project.

14 Jun 2021

Soft diets may alter the brain's control of chewing, study finds

Incoming sensory information can affect the brain's structure, which may in turn affect the body's motor output. However, the specifics of this process are not always well understood.

9 Jun 2021