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Unraveling the mystery of viral evolution

All organisms - from fungi to mammals - have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with the ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

Austocystin D's anticancer efficacy linked to CYP2J2 enzyme activity

Austocystin D, a natural compound produced by fungi, has been recognized for its cytotoxic effects and anticancer activity in various cell types. It exhibits potent activity even in cells that express proteins associated with multidrug resistance, attracting significant global research interest.

27 Aug 2024

Understanding host immune responses through cell death pathways

A new review was published as the cover paper of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 15, entitled, "Types of cell death and their relations to host immunological pathways".

16 Aug 2024

X-ray irradiation emerges as a new tool to combat aflatoxin-contaminated corn

Corn, a staple food crop consumed by billions of people and animals worldwide, is frequently contaminated by the fungal toxin aflatoxin B1, a highly potent carcinogen produced by the fungus Aspergillus flavus.

16 Aug 2024

New model for ventilator-associated pneumonia reveals path to improved treatments

Scientists at The University of Warwick have made a breakthrough which could help find new treatments for a deadly infection that can affect up to 40% of hospital patients using mechanical ventilators.

16 Aug 2024

Midlife and early senior years marked by dramatic molecular shifts

If it's ever felt like everything in your body is breaking down at once, that might not be your imagination. A new Stanford Medicine study shows that many of our molecules and microorganisms dramatically rise or fall in number during our 40s and 60s.

14 Aug 2024

Discovery of immune cell regulator could lead to new therapies for inflammatory conditions

The discovery of a new regulator affecting immune cells could lead to new treatments to reduce inflammation in diseases including arthritis and severe COVID 19.

14 Aug 2024

Study finds minimal impact of cesarean antibiotics on infant gut microbiome

Cesarean section recipients are usually given prophylactic antibiotics just before the procedure to prevent later infections at the surgical site.

14 Aug 2024

Breakthrough in synthesizing complex plant molecules

MIT chemists have developed a new way to synthesize complex molecules that were originally isolated from plants and could hold potential as antibiotics, analgesics, or cancer drugs.

14 Aug 2024

Breakthrough in the synthesis of fungal bioactive compounds for therapeutic applications

The natural world is rich in chemical compounds with remarkable medicinal properties. A notable example is penicillin, discovered by chance from the Penicillium mold.

9 Aug 2024

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

Emory researcher David Weiss has spent years studying a baffling phenomenon called heteroresistance, in which a tiny fraction of bacteria remain resistant to antibiotics, while the remainder succumb.

2 Aug 2024

Advanced imaging techniques shed light on single cells

Every plant, animal, and person is a rich microcosm of tiny, specialized cells. These cells are worlds unto themselves, each with their own unique parts and processes that elude the naked eye.

2 Aug 2024

Mast cells found to capture and employ neutrophils during allergic reactions

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system.

2 Aug 2024

Fecal microbiota transplants can boost the effectiveness of immunotherapy in gastrointestinal cancers

Findings from a small, proof-of-concept clinical trial have suggested that fecal microbiota transplants (FMTs) can boost the effectiveness of immunotherapy in a range of gastrointestinal cancers.

25 Jul 2024

How indoor microbiomes shape our health and well-being

Indoor microbiomes, influenced by urbanization and building design, significantly impact human immune, neurological, and endocrine health. This research emphasizes the need for innovative approaches to harness these microbial ecosystems for improved public health outcomes.

24 Jul 2024

Tiny animals steal antibiotic secrets from bacteria to fight disease

A group of small, freshwater animals protect themselves from infections using antibiotic recipes "stolen" from bacteria, according to new research by a team from the University of Oxford, the University of Stirling and the Marine Biological Laboratory (MBL), Woods Hole.

19 Jul 2024

fungi News and Research

Unraveling the mystery of viral evolution

Austocystin D's anticancer efficacy linked to CYP2J2 enzyme activity

Understanding host immune responses through cell death pathways

X-ray irradiation emerges as a new tool to combat aflatoxin-contaminated corn

New model for ventilator-associated pneumonia reveals path to improved treatments

Midlife and early senior years marked by dramatic molecular shifts

Discovery of immune cell regulator could lead to new therapies for inflammatory conditions

Study finds minimal impact of cesarean antibiotics on infant gut microbiome

Breakthrough in synthesizing complex plant molecules

Breakthrough in the synthesis of fungal bioactive compounds for therapeutic applications

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

Advanced imaging techniques shed light on single cells

Mast cells found to capture and employ neutrophils during allergic reactions

Fecal microbiota transplants can boost the effectiveness of immunotherapy in gastrointestinal cancers

How indoor microbiomes shape our health and well-being

Tiny animals steal antibiotic secrets from bacteria to fight disease

How your diet shapes your gut microbiome and impacts your health

Unveiling the zoonotic web: Understanding complex interactions involved in zoonoses

Archaeal, fungal, viral, as well as bacterial, functional makers for autism spectrum disorder in children

How Aloe vera's medicinal properties make it essential in medicine, cosmetics, and food products

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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