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Bacteria use dormant phages to create immunity against viral invaders

Like people, bacteria get invaded by viruses. In bacteria, the viral invaders are called bacteriophages, derived from the Greek word for bacteria-eaters, or in shortened form, "phages."

22 Mar 2025

Groundbreaking study unveils key mechanism for neuronal identity regulation

A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, in collaboration with researchers from Columbia University (New York, USA), has identified a mechanism that regulates the production of two different proteins from the same gene.

22 Mar 2025

New drug combination shows promise in treating melanoma brain metastasis

A federally funded research team led by Sheri Holmen, PhD, investigator at Huntsman Cancer Institute and professor in the Department of Surgery at the University of Utah (the U), is testing a new combination drug therapy that could both treat and prevent melanoma metastasis, or spreading from its original site, to the brain.

21 Mar 2025

Circadian rhythms play a crucial role of in regulating tumor progression

Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external light-dark cycles.

21 Mar 2025

Scientists decode differentiation pathways of human blood stem cells

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ.

21 Mar 2025

Cellular models of embryos offer insights into early developmental processes

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery.

20 Mar 2025

Genomic screening reveals hidden health risks of patients

Genetic information collected through research studies like Geisinger's MyCode Community Health Initiative can provide important-and previously unknown-information to participants about their risk for disease.

20 Mar 2025

New discovery shows piRNA's adaptive role in silencing jumping genes

Adverse genetic mutations can cause harm and are due to various circumstances. "Jumping genes" are one cause of mutations, but cells try and combat them with a specialized RNA called piRNA.

20 Mar 2025

High-fat diet impairs neutrophil function in obesity

A new study in The Journal of Immunology reveals how a high-fat diet may impair the immune system's ability to respond to infection by impacting the function of neutrophils, one of the first immune cells to respond to bacteria or viruses.

20 Mar 2025

Researchers reveal link between placental DNA methylation and neuropsychiatric disorders

An international team led by UPV/EHU and Biobizkaia reveals the relationship between placental DNA methylation and certain neuropsychiatric disorders.

20 Mar 2025

New function of Exportin-1 discovered in gene transcription

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell nuclei of all flora and fauna.

20 Mar 2025

Yale scientists develop advanced CRISPR tool to study complex genetic interactions

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.

20 Mar 2025

Cell map offers insights into endometrial dysfunction in women with PCOS

Women with polycystic ovary syndrome (PCOS) find it harder to get pregnant, have more frequent miscarriages and have a higher risk of developing endometrial cancer.

20 Mar 2025

Targeted inhibition of a 'signal jammer' protein may improve tumor response to immunotherapy

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein voltage-dependent anion channel 2 (VDAC2) like a signal jammer to prevent the body's anticancer systems from communicating with the immune system.

19 Mar 2025