Immune Response News and Research

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Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Researchers used whole genome sequencing to evaluate monkeypox virus samples from Washington and Ohio states in the United States and identified 25 samples with open reading frame (ORF)-disrupting mutations.

7 Nov 2022

Transcriptomic dysregulation across cerebral cortex in autism spectrum disorder

A new study demonstrated transcriptomic dysregulation in the cerebral cortex in autism spectrum disorder (ASD).

7 Nov 2022

HPV vaccine rates in Utah increase by more than 16% among young men and women, CDC data reveals

When life should have been ripe with possibilities, Mandy Murry instead faced a devastating diagnosis. Murry was diagnosed with cervical cancer when she was 22.

4 Nov 2022

Study evaluates BA.5-bivalent booster against new Omicron sublineages

In a new study, researchers evaluated the efficacy of four doses of parental messenger ribonucleic acid (mRNA) vaccine and a BA.5-bivalent booster against recently emerged Omicron sublineages. Additionally, they determined whether prior infection improved the effect of a booster vaccination.

4 Nov 2022

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Monkeypox has infected more than 77,000 people in more than 100 countries worldwide, and - similar to COVID-19 - mutations have enabled the virus to grow stronger and smarter, evading antiviral drugs and vaccines in its mission to infect more people.

4 Nov 2022

Health of mothers, fetuses, and children are all affected by the maternal environment

A recent editorial published in the journal BMC Medicine examined existing literature for associations between the mother's and offspring's health outcomes and a broad range of maternal characteristics related to pregnancy and postnatal phenotypes and complications.

3 Nov 2022

Vaccination with senescent cells could be a possible therapy against cancer

Cancer cells have a series of features that allow the immune system to identify and attack them. However, these same cells create an environment that blocks immune cells and protects the tumor.

3 Nov 2022

Researchers shed light on the key functions of innate immune cells

Inflammation and increased mucus production are typical symptoms of worm infections and allergies. This immune response involves our innate immune cells, but their exact functions are not yet fully understood.

3 Nov 2022

New insights into the dynamic inner world of the human immune system

As researchers glean new insights into the dynamic inner world of the human immune system, it has become increasingly clear that mitochondria are critical regulators of how our bodies respond to disease.

3 Nov 2022

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell's Ithaca campus.

2 Nov 2022

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Innate lymphoid cells are a recently discovered family of white blood cells that reside in the skin, gastrointestinal tract, airways and other barrier tissues of the body.

2 Nov 2022

Researchers corroborate the importance of exercise for cognitive function

Accumulating evidence finds that exercise can improve brain function and delay or prevent the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

2 Nov 2022

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

Researchers examined how imprinted SARS-CoV-2 humoral immunity drives convergent evolution in continuously emerging Omicron subvariants.

2 Nov 2022

New analysis on the risk for myocarditis or pericarditis after mRNA COVID-19 vaccination

A comprehensive review and meta-analysis of published research confirm that young adults (40 years old and younger) have a slightly elevated risk for myocarditis or pericarditis after mRNA COVID-19 vaccination.

1 Nov 2022

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation.

1 Nov 2022

Researchers find the root of immunosuppression and chemoresistance in TNBC tumors

Triple-negative breast cancer (TNBC) tumors gain immunosuppression and chemoresistance through interactions between interleukin 34 and myeloid-derived suppressor cells, researchers find.

1 Nov 2022

New nanovaccine greatly improves cytokine production

Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer. However, immune checkpoint inhibition therapy is only effective in 20%–30% of cancer patients, so developing better drug delivery systems to induce anticancer cellular immunity is necessary.

1 Nov 2022

Researchers develop special molecules that stimulate the immune system

Surgery, radiation, and chemotherapy are the three main therapies used to treat cancerous tumors. The doctoral research network 'Magicbullet::Reloaded'is investigating another approach, with 15 doctoral researchers developing special molecules that stimulate the immune system to destroy tumor cells. In a video, network members explain how doctoral researchers gain valuable experience and research opportunities as part of the network.

1 Nov 2022

Artificial intelligence-based method may help predict early-stage melanoma recurrence

Most deaths from melanoma - the most lethal form of skin cancer - occur in patients who were initially diagnosed with early-stage melanoma and then later experienced a recurrence that is typically not detected until it has spread or metastasized.

31 Oct 2022

Immune Response News and Research

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Transcriptomic dysregulation across cerebral cortex in autism spectrum disorder

HPV vaccine rates in Utah increase by more than 16% among young men and women, CDC data reveals

Study evaluates BA.5-bivalent booster against new Omicron sublineages

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Health of mothers, fetuses, and children are all affected by the maternal environment

Vaccination with senescent cells could be a possible therapy against cancer

Researchers shed light on the key functions of innate immune cells

New insights into the dynamic inner world of the human immune system

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Researchers corroborate the importance of exercise for cognitive function

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

New analysis on the risk for myocarditis or pericarditis after mRNA COVID-19 vaccination

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

Researchers find the root of immunosuppression and chemoresistance in TNBC tumors

New nanovaccine greatly improves cytokine production

Researchers develop special molecules that stimulate the immune system

Artificial intelligence-based method may help predict early-stage melanoma recurrence

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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