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An assessment of potential epitopes in SARS-CoV-2 structural proteins

Researchers utilized multiple bioinformatics resources to identify potent T- and B-cell epitopes of four SARS-CoV-2 structural proteins.

24 Nov 2021

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Researchers conducted a study on COVID-19 convalescent patients and post-vaccinated populations to identify the minimal levels of antibody required to protect against SARS-CoV-2 infection.

24 Nov 2021

Bat coronavirus ecology, evolution, and spillover

In a review published in Nature Reviews Microbiology, the authors collate information about the ecology and evolution of bat coronaviruses.

24 Nov 2021

Study offers insights into how Shigella delivers bacterial proteins into our cells

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells.

24 Nov 2021

CDC study finds Pfizer-BioNTech COVID vaccine provides high protection against hospitalization in adolescents

New research from the Centers for Disease Control & Prevention (CDC) suggest vaccines are highly protective against severe acute respiratory coronavirus 2 (SARS-CoV-2). Two doses of the Pfizer-BioNTech vaccine showed a 93% effectiveness against hospitalization. The findings add to a previous clinical trial that found vaccinated adolescents with 100% protection against SARS-CoV-2 infections.

23 Nov 2021

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

A new study, published on the bioRxiv* preprint server, has discovered a class of new immunostimulatory RNAs while studying influenza infection-associated host genes in human lung epithelial cells using small interfering RNAs (siRNAs). Scientists revealed that these short duplex RNAs could induce type I and type III interferons (IFN-I/III) in a wide variety of cells.

23 Nov 2021

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Scientists investigate the neuroinvasive potential of SARS-CoV-2 and the role of tunneling nanotubes (TNTs) in spreading the infection to neighboring cells.

23 Nov 2021

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

New research suggests that SARS-CoV-2 infection can directly target and cause cellular damage to the adrenal glands.

23 Nov 2021

Singapore researchers develop ultra-sensitive 2D material sensor to detect breast cancer cells

Cells can produce unique electrical signals. These signals can be linked to various cancers, such as the breast, lung, liver, brain, pancreas and prostate cancers, meaning that they can be used as indicators for early cancer diagnosis.

22 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Researchers synthesize carbon dots using different precursors and studied their antimicrobial effects in gram-negative bacteria.

22 Nov 2021

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

A new review article determines the role of UV disinfection for nosocomial transmission of COVID-19 and other infectious diseases.

22 Nov 2021

Naturally occurring phage A1-1 kills dysentery-causing bacteria in sub-Saharan Africa, southern Asia

Phages are viruses that infect bacteria and can also be used to treat human infections. However, as with antibiotics, bacteria can readily evolve resistance to phage attack, highlighting a key limitation to the use of phages as therapeutics.

21 Nov 2021

Novel technique solves structure of the HIV capsid alone and in complex with host factors

A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.

21 Nov 2021

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting the cells that produce mucus, sweat, and digestive juices.

21 Nov 2021

UC researchers engineer new probiotic to target and break down cancer cell defenses

Bacteria generally have a bad reputation, as people first think of certain strains that can cause serious illnesses like pneumonia or meningitis. However, there are many helpful bacteria, known as probiotics, that assist the body in different ways.

21 Nov 2021

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

In a review published in Signal Transduction and Targeted Therapy, researchers from Sichuan University have reviewed the available literature.

19 Nov 2021

Viral biomolecular condensation

A review published in PLOS Pathogens deconstructs virus condensation and provides a biochemical background for LLPS.

19 Nov 2021

Structure of SARS-CoV-2 spike protein postfusion

A new study published in PNAS proposes a higher resolution in situ structure of the SARS-CoV-2 spike protein in its postfusion state.

18 Nov 2021

Toll-like receptor 2 - novel target for improved COVID-19 vaccines

In a new study, researchers from French and American institutes analyzed at a molecular level the interaction between SARS-CoV-2 E protein and human TLR2.

17 Nov 2021

Membrane News and Research

An assessment of potential epitopes in SARS-CoV-2 structural proteins

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Bat coronavirus ecology, evolution, and spillover

Study offers insights into how Shigella delivers bacterial proteins into our cells

CDC study finds Pfizer-BioNTech COVID vaccine provides high protection against hospitalization in adolescents

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

Singapore researchers develop ultra-sensitive 2D material sensor to detect breast cancer cells

Paper-based innovations for COVID-19 diagnosis

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

Naturally occurring phage A1-1 kills dysentery-causing bacteria in sub-Saharan Africa, southern Asia

Novel technique solves structure of the HIV capsid alone and in complex with host factors

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

UC researchers engineer new probiotic to target and break down cancer cell defenses

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

Viral biomolecular condensation

Structure of SARS-CoV-2 spike protein postfusion

Toll-like receptor 2 - novel target for improved COVID-19 vaccines

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

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