Proliferation News and Research

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New study helps explain why lung tumors turn aggressive

Lung cancer is the number 1 killer among cancers, especially when it is of the non-small cell type. Among these, adenocarcinomas are the most common and aggressive type. These tumors also show a strong tendency to show dedifferentiation, or loss of the features that characterize a mature lung cell.

28 Aug 2019

Scientists reveal cancer cells' immune weak spot

Scientists have found a vulnerability in cancer cells that could make them more susceptible to being destroyed by the immune system, according to a new report in eLife.

27 Aug 2019

Polycystic kidney disease may be preventable

Kidney failure is a lifelong burden in hundreds of thousands of people who need to be treated either by dialysis or a kidney transplant. Both procedures significantly increase the cost of healthcare and reduce the quality of life.

26 Aug 2019

Ketogenic diet shown to support intestinal stem cells

Scientists have discovered that ketone bodies produced during the ketogenic diet trigger the proliferation of intestinal stem cells in adults.

26 Aug 2019

Researchers target cancer's protective barrier

Cancer cells are notorious for their camouflage work, which enables them to escape immune targeting. Now scientists are learning how to strip away the disguise and allow the immune system to do its work, by targeting cells called myeloid-derived suppressor cells (MDSCs) that shield the tumor. This would also enhance the effectiveness of newer cancer immunotherapies like Chimeric-Antigen Receptor T cell (CAR-T).

26 Aug 2019

Enzyme induced by stress associated with liver cancer growth

An enzyme induced by stress to help reduce production of damaging free radicals is also used by liver cancer to regulate two major cell proliferation pathways that enable the cancer to thrive, scientists report.

22 Aug 2019

Patient-reported experiences have potential for driving improvements in hospital care

Patient-reported experiences have potential for driving improvements in the quality of hospital care, according to a new study in the Canadian Journal of Cardiology, published by Elsevier.

22 Aug 2019

New cannabis-based drug shows promise for pancreatic cancer

Cancer of the pancreas is a particularly deadly cancer, claiming over 90% of its victims within 5 years from diagnosis. It resists most standard therapies, including surgery, chemotherapy, radiation therapy, immunotherapy and targeted therapy, and metastasizes early, often before being diagnosed. A cure is possible only with very localized tumors.

22 Aug 2019

International study identifies new drug target for treating glioblastoma

A new international study co-led by Cleveland Clinic has identified a new drug target for treating glioblastoma. This target is part of a never-before defined cellular pathway found to contribute to the spread and proliferation of a dangerous subset of cancer cells, called glioma stem cells.

22 Aug 2019

Roswell Park receives more than $15 million in grants for cancer research

Roswell Park Comprehensive Cancer Center researchers have received more than a dozen recent grant awards totaling more than $15.4 million.

14 Aug 2019

Researchers seek to understand the regenerative potential of newborn mammalian hearts

Unlike lower vertebrates, mammals are unable to repair their adult hearts after injuries that include heart attacks. This inability in humans leads to heart failure -- a deadly and costly disease that affects more than 5 million Americans.

10 Aug 2019

Study reveals Lassa virus' soft spot

As this year's Lassa fever outbreak in Nigeria is finally ebbing, the total tally came to more than 600 infected people, one-quarter of them dead. Thousands more die each year, uncounted in rural villages throughout West Africa.

9 Aug 2019

Thymol antimicrobial in corn starch can help fight mosquito-borne diseases

The Aedes aegypti mosquito is the major vector for many urban arboviruses, which can cause serious conditions such as dengue fever, Zika virus, Chikungunya, and yellow fever. Now, researchers have developed a cheap but effective larvicide using cornstarch.

7 Aug 2019

Researchers open up possible avenue for new cancer treatments without side effects

Researchers have opened up a possible avenue for new cancer therapies that don't have the side effects that oftentimes accompany many current cancer treatments by identifying a protein modification that specifically supports proliferation and survival of tumor cells.

6 Aug 2019

International collaborative pinpoints key areas to catalyze nutrition-based cancer prevention

An international collaborative led by Ludwig Cancer Research and Cancer Research UK has identified key areas that are central to uncovering the complex relationship between nutrition and cancer.

31 Jul 2019

New device traps and analyzes single cells for faster HPV-related cervical cancer screening

Several screening tests for cervical cancer have been developed in recent years. One technique uses immunofluorescent staining to determine the levels of biomarkers to indicate a cell is undergoing HPV-related cancerous growth.

31 Jul 2019

Herbal medicine for preventing, healing vascular diseases

The system connects the arteries to the veins. There are 100,000 miles of blood vessels in the adult human body.

30 Jul 2019

Mechanical forces regulate cellular behavior during embryonic development of the brain

A new study coordinated by the Research Group in Developmental Biology at UPF shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during morphogenesis to regulate the balance between progenitor stem cells and differentiated neurons.

29 Jul 2019

Study finds specific direct targets for lung cancer treatment

A team of researchers at the Salk Institute has found two therapeutic targets for the deadly type of lung cancer, non-small-cell lung carcinomas (NSCLCs), which accounts for 85 percent of all lung cancer cases. They believe that the breakthrough discovery could pave the way for the development of new treatments for a majority of lung cancer patients.

29 Jul 2019

Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving the drug during early gestation.

24 Jul 2019