Protein C News and Research

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Alzheimer's disease linked to disrupted brain oxygenation and neuronal function

Research led by Lancaster University has revealed clear evidence that changes in the orchestration of brain oxygenation dynamics and neuronal function in Alzheimer's disease contribute to the neurodegeneration.

3 Feb 2025

Researchers develop model to identify tumor-fighting immune cells in lung cancer patients

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.

3 Feb 2025

Study reveals mechanism behind CAR molecule transfer in cancer therapy

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now discovered that CAR molecules can be transferred from the CAR-T cells to other T cells in the tumour microenvironment.

3 Feb 2025

Single heat stroke exposure triggers long-term health risks and metabolic vulnerabilities

The study links exertional heat stroke to chronic disorders, revealing impacts on body mass regulation and heart health, especially in high-fat diet scenarios.

3 Feb 2025

Improving insulin sensitivity with regular mango consumption

The regular consumption of mangoes may improve inflammation, insulin sensitivity, and glucose control.

3 Feb 2025

Does COVID increase the risk of Alzheimer’s disease?

COVID-19, even in mild cases, is linked to changes in Alzheimer’s disease-related brain biomarkers comparable to four years of aging. This study raises concerns about long-term neurological risks and cognitive decline post-COVID.

2 Feb 2025

Immune system discovery could revolutionize treatment for chronic disease and cancer

A discovery about the mechanisms that enable the immune system to sustain long-term protection could revolutionize treatment for chronic disease and cancer.

31 Jan 2025

Study could help predict treatment response for KRASG12C-mutant non-small cell lung cancer

A new study from Moffitt Cancer Center could help doctors predict how well patients with a specific type of lung cancer will respond to new therapies.

31 Jan 2025

UIC scientists redesign asparaginase to minimize leukemia treatment side effects

University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage.

31 Jan 2025

New microscopy technique uncovers 'ribosome cooperativity' in difficult situations

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells.

31 Jan 2025

New findings could make off-the-shelf CAR T cell therapy a reality

CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient's own immune T cells and engineering them to recognize specific targets on the surface of the cancer cell.

31 Jan 2025

Duke engineers develop AI platform to target undruggable disease proteins

Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing proteins.

31 Jan 2025

Revolutionizing diabetes care with innovative targets and therapeutic options

A thorough examination of modern drugs that target particular receptors and metabolic pathways for glucose and fat metabolism is presented. Recent research has revealed innovative targets and therapeutic options.

30 Jan 2025

Alzheimer’s and Parkinson’s linked to aging brain’s failing waste disposal

New research uncovers how declining protein clearance mechanisms with age lead to Alzheimer’s, Parkinson’s, and other neurodegenerative diseases—offering hope for targeted therapies to slow or prevent these conditions.

30 Jan 2025

New light-controlled tools offer real-time protein control in living cells

A research group at Umeå University has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells.

30 Jan 2025

Zika virus manipulates human skin to attract mosquitoes and boost transmission

Zika virus hijacks the skin of its human host to send out chemical signals that lure more mosquitoes to infect and spread the disease further, new research shows.

30 Jan 2025

How your immune system ages: Scientists reveal key changes over a lifetime

Scientists mapped how the human immune system evolves from birth to old age, revealing key changes that influence health, disease resistance, and aging. Their immune age model could help predict immune health and guide early interventions.

30 Jan 2025

ALPK2 identified as promising new therapeutic target for treatment of heart failure

Tatsuya Yoshida, Mikito Takefuji, and Toyoaki Murohara in the Department of Cardiology, Nagoya University Graduate School of Medicine, identified an enzyme, alpha-kinase 2 (ALPK2) that is specifically expressed in the heart.

30 Jan 2025

Rapid blood test could identify brain bleeds from clot-caused strokes

A blood test may rapidly distinguish brain bleeds from clot-caused strokes, even before people with stroke symptoms reach the emergency room, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2025.

30 Jan 2025

New insights into mechanisms of mucosal mast cells in food allergies

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially life-threatening

29 Jan 2025