Therapy News and Research

RSS

Multi-purpose protein may offer clues for successful treatment of Alzheimer's disease

The tidal wave approaches. In the coming decades, Alzheimer's disease is projected to exact a devastating economic and emotional toll on society, with patient numbers in the US alone expected to reach 13.5 million by mid-century at a projected cost of over a trillion dollars.

30 Aug 2016

REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

A clinical decision rule (CDR) that can be applied to women after a first, unprovoked venous thromboembolism (VTE) was able to identify those with a low-risk of recurrence who could safely discontinue anticoagulant therapy, researchers reported at ESC Congress 2016.

30 Aug 2016

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

Previous studies at the University of Colorado Cancer Center show that the experimental drug AMPI-109 potently kills triple-negative breast cancer cells.

30 Aug 2016

New anticoagulant treatment safe and effective for AF patients before cardioversion

Patients with atrial fibrillation (AF) who need anticoagulation before undergoing electrical correction of their abnormal heartbeat (cardioversion) may benefit from treatment with edoxoban - a non-vitamin K antagonist (VKA) oral anticoagulant (NOAC), according to results of the ENSURE-AF trial.

30 Aug 2016

MedUni Vienna scientists aim to identify prognostic markers for cutaneous lymphomas

Primary cutaneous lymphomas, cancers of the lymphatic system, occur in the skin and originate either from T-lymphocytes (T-cell lymphomas, incidence 75%) or in B-cell lymphocytes (B-cell lymphomas, 25%).

30 Aug 2016

New study suggests major change in treatment of significant number of ACS patients

More than one quarter of heart attack patients who are normally treated with stents to re-open their blocked arteries might be able to forgo this procedure and receive anti-thrombotic medications only, according to results of a pilot study.

30 Aug 2016

Penn scientists find striking similarities between human patients with LCA and dogs

Ciliopathies are diseases that affect the cilia, sensory organelles that most mammalian cells possess and which play a critical role in many biological functions.

30 Aug 2016

Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Nebivolol prevents anthracycline-induced cardiotoxicity, according to research presented at ESC Congress 2016 today by Professor Mirela Cleopatra Tomescu, a cardiologist at Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.

30 Aug 2016

Could a light-listening photonics device detect skin disease? An interview with Prof. Vasilis Ntziachristos

Detection of malignant skin alterations is currently aided by optical microscopes such as dermoscopes or optical microscopes. While the latter offers high resolution, it comes with a major disadvantage, just like any other purely microscopic method: it only provides a partial view of the skin due to the low penetration depth.

29 Aug 2016

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researchers at the National Center for Advancing Translational Sciences recently identified compounds that potentially can be used to inhibit Zika virus replication and reduce its ability to kill brain cells.

29 Aug 2016

Researcher receives NIH grant to detect increasing Mtb activity in people with HIV

Tuberculosis (TB) is the leading cause of death worldwide among people infected with HIV.

29 Aug 2016

Novel drug-dispensing contact lens effective in providing better pressure reduction in glaucoma model

A contact lens designed to deliver medication gradually to the eye could improve outcomes for patients with conditions requiring treatment with eye drops, which are often imprecise and difficult to self-administer.

29 Aug 2016

Adults with moderate to severe TBI may be at greater risk of death from unintentional injuries

Research examining adults with moderate to severe traumatic brain injury (TBI) who participated in rehabilitation showed that they were twice as likely to die from an unintentional injury that occurred following their TBI.

29 Aug 2016

Fluid-filled sacs that brain cells make to trap amyloid may contribute to Alzheimer's disease

Vesicles, fluid-filled sacs that brain cells make to trap amyloid, a hallmark of Alzheimer's, appear to also contribute to the disease, scientists report.

29 Aug 2016

Platelet function testing in elderly patients after heart attack shows no improved outcomes

Monitoring platelet function in order to individualize antiplatelet therapy did not improve outcomes for elderly patients after a heart attack compared to a standard, unmonitored approach, results of the ANTARCTIC trial show.

29 Aug 2016

$Lipoprotein apheresis may have new role in patients with refractory angina$

Lipoprotein apheresis may have new role in patients with refractory angina

Initial investigation of patients with suspected coronary heart disease (CHD) using functional imaging - rather than guideline-directed care - resulted in significantly less unnecessary angiography, according to results of the CE-MARC 2 trial.

29 Aug 2016

Active strategy of detecting and treating asymptomatic MSAD results in no clinical benefit

In patients with high-risk coronary artery disease (CAD), an active strategy of detecting and treating asymptomatic multisite artery disease (MSAD) combined with intensive medical therapy did not improve 2-year outcomes compared to a more traditional approach of managing only symptomatic coronary and extracoronary lesions, new research shows.

29 Aug 2016

Remote monitoring shows no improvement in outcomes for heart failure patients with CIEDs

For heart failure patients with cardiac implantable electronic devices (CIEDs), remote monitoring of their condition does not improve outcomes compared to usual care, according to Hot Line results presented at ESC Congress 2016 and to be simultaneously published in JAMA.

29 Aug 2016

HIJ-PROPER trial: Intensive cholesterol-lowering regimen in ACS patients shows no better outcomes

Survival and other cardiovascular outcomes were not significantly reduced with intensive treatment using a second-line cholesterol-lowering medication on top of a standard statin, compared to statin treatment alone in patients with acute coronary syndrome (ACS) and dyslipidemia, investigators reported here.

29 Aug 2016

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

A single dose of mesenchymal stem cells delivered intravenously to patients with chronic non-ischemic cardiomyopathy was not associated with significant cardiac structural or functional improvements, but did result in several clinically relevant benefits, according to results from a phase II-a randomized trial.

29 Aug 2016

Therapy News and Research

Multi-purpose protein may offer clues for successful treatment of Alzheimer's disease

REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

New anticoagulant treatment safe and effective for AF patients before cardioversion

MedUni Vienna scientists aim to identify prognostic markers for cutaneous lymphomas

New study suggests major change in treatment of significant number of ACS patients

Penn scientists find striking similarities between human patients with LCA and dogs

Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Could a light-listening photonics device detect skin disease? An interview with Prof. Vasilis Ntziachristos

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researcher receives NIH grant to detect increasing Mtb activity in people with HIV

Novel drug-dispensing contact lens effective in providing better pressure reduction in glaucoma model

Adults with moderate to severe TBI may be at greater risk of death from unintentional injuries

Fluid-filled sacs that brain cells make to trap amyloid may contribute to Alzheimer's disease

Platelet function testing in elderly patients after heart attack shows no improved outcomes

Lipoprotein apheresis may have new role in patients with refractory angina

Active strategy of detecting and treating asymptomatic MSAD results in no clinical benefit

Remote monitoring shows no improvement in outcomes for heart failure patients with CIEDs

HIJ-PROPER trial: Intensive cholesterol-lowering regimen in ACS patients shows no better outcomes

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News