Immune System News and Research

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Discoveries on anti-HIV antibodies may help researchers create an effective HIV vaccine

New discoveries about anti-HIV antibodies may bring researchers a step closer to creating an effective HIV vaccine, according to a new paper co-authored by scientists at the Vaccine Research Center of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

20 Nov 2009

Pediatric immunologist receives prestigious annual award from American Philosophical Society

A pediatric immunologist at The Children's Hospital of Philadelphia has received a prestigious annual award from the American Philosophical Society, an organization founded in 1743 by Benjamin Franklin. Jordan S. Orange, M.D., Ph.D., received the Society's Judson Daland Prize on Nov. 13 for his contributions to research and treatment of inherited immune deficiency diseases.

20 Nov 2009

Sugar-coated polymer may offer a new solution for allergy and asthma

Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks. Their advance is a significant step toward crafting pharmaceuticals to fight these often life-endangering conditions in a new way.

20 Nov 2009

GERD is an immune-mediated injury and not the result of acid burn, says new study

Contrary to current thinking, a condition called gastroesophageal reflux disease (GERD) might not develop as a direct result of acidic digestive juices burning the esophagus, UT Southwestern Medical Center researchers have found in an animal study.

20 Nov 2009

H1N1: Bridging the knowledge gap

A commentary in the December issue of The Lancet Infectious Diseases brings to light the gaps in knowledge on the transmission of a common pathogen - the influenza virus - and its impact on decisions about how best to protect health care workers. Infectious diseases specialist Leonard Mermel, DO, medical director of infection control for Rhode Island Hospital, looks at the ongoing debate in light of the H1N1 pandemic, what past research tells us about the spread of influenza, and what is missing in the debate. His commentary is currently available in an online first edition.

20 Nov 2009

Adamas Pharmaceuticals expands its Phase 2 TCAD therapy study for influenza A

Adamas Pharmaceuticals, Inc., a privately held company, announced today that it has expanded its Phase 2 clinical study of a proprietary investigational triple-combination antiviral drug therapy for influenza to include centers in the United States, Canada and Europe. The study, which was initiated in August 2009 in the Southern Hemisphere, is designed to investigate Adamas' triple combination antiviral drug (TCAD) therapy as a treatment for influenza A, including novel influenza A/H1N1, the cause of the current flu pandemic.

19 Nov 2009

ISCO, Scripps Research Institute collaborate in study of parthenogenetic stem cells

International Stem Cell Corporation, announced today that it is collaborating with renowned stem cell researcher Jeanne F. Loring, Ph.D., and the Scripps Research Institute (La Jolla, CA) to study parthenogenetic stem cells and potentially therapeutic cells that can be derived from them.

19 Nov 2009

Exaggerated responses of immune system explain elders’ susceptibility to viral infections

Researchers at Yale School of Medicine have found that exaggerated responses of the immune system explain why the elderly succumb to viral infections more readily than younger people. Published in the November 19 Cell Host & Microbe, the study bucks the general belief that declining immune responses are to blame for susceptibility to viral infections.

19 Nov 2009

NanoString Technologies to investigate molecular networks with the Broad Institute of MIT and Harvard

NanoString Technologies, Inc., a privately held life sciences company marketing a molecular barcoding detection system, today announced that it is collaborating with the Broad Institute of MIT and Harvard to investigate molecular networks involved in immune response and other important biological processes.

From NanoString Technologies 19 Nov 2009

Genetic identity of cellular receptor for the immune system's first-response antibody discovered

Researchers at the University of Alabama at Birmingham (UAB) have uncovered the genetic identity of a cellular receptor for the immune system's first-response antibody, a discovery that sheds new light on infection control and immune disorders. The discovery is such a crucial part of immunology that UAB researchers, in conjunction with Japanese researchers, are asking that the gene linked to this antibody receptor be renamed to better describe its role in early immune responses.

19 Nov 2009

UNGASS monitoring system provides the overall progress in the global response to HIV

Although much work remains to be done, a United Nations global reporting system on HIV/AIDS has already yielded an "unequaled wealth of data" on progress toward meeting UN targets for responding to the global HIV epidemic. An update on the development of the UN General Assembly Special Session on HIV/AIDS (UNGASS) global reporting system appears in a special supplement to JAIDS: Journal of Acquired Immune Deficiency Syndromes.

19 Nov 2009

Opiate-based painkillers can increase tumor-cell proliferation, says new study

Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells.

19 Nov 2009

Protein content of women's saliva changes with advancing age, describe scientists

In a step toward using human saliva to tell whether those stiff joints, memory lapses, and other telltale signs of aging are normal or red flags for disease, scientists are describing how the protein content of women's saliva change with advancing age.

19 Nov 2009

Results from Phase IIa clinical trial evaluating VT-111 reported by Viron Therapeutics

Viron Therapeutics Inc., a biotechnology company pioneering the development of immune-modulating protein therapeutics derived from pathogens, today reported results from a Phase IIa clinical trial evaluating VT-111 (Serp-1), an anti-inflammatory protein derived from the myxoma virus.

19 Nov 2009

U.S. health officials testify before Senate Committee about H1N1 vaccine campaign

U.S. health officials defended their handling of the country's H1N1 (swine flu) vaccine campaign Tuesday "against criticism that their plan to protect Americans was confusing and over-optimistic," Reuters reports (Fox, 11/17).

18 Nov 2009

Patients with recent-onset schizophrenia have raised levels of inflammatory substances

Researchers at the Swedish medical university Karolinska Institutet have discovered that patients with recent-onset schizophrenia have higher levels of inflammatory substances in their brains. Their findings offer hope of being able to treat schizophrenia with drugs that affect the immune system.

18 Nov 2009

CEL-SCI commences clinical study of LEAPS-H1N1 treatment for hospitalized patients

CEL-SCI Corporation, a developer of vaccines and therapeutics for the prevention and treatment of infectious diseases and a late-stage oncology company, announced today the start of the Company's first clinical study for hospitalized H1N1 patients at The Johns Hopkins University School of Medicine (Johns Hopkins).

18 Nov 2009

Researchers identify new way to capture tumor cells in bloodstream; findings can improve early cancer diagnosis

Jin-Woo Kim, a biomedical engineering researcher at the University of Arkansas, is part of a cutting-edge nanotechnology research group that has discovered a way to capture tumor cells in the bloodstream. The work could dramatically improve early cancer diagnosis and prevent deadly metastasis.

18 Nov 2009

MPI scientists identify mechanism that demonstrates immune cell movement on diverse surfaces

Scientists from the Max Planck Institute (MPI) of Biochemistry in Martinsried near Munich, Germany, have now deciphered the mechanism that illustrates how these mobile cells move on diverse surfaces. "Similar to a car, these cells have an engine, a clutch and wheels which provide the necessary friction," explains Michael Sixt, a research group leader at the MPI of Biochemistry.

18 Nov 2009

SynCon Chikungunya virus DNA vaccine induces protective neutralizing antibody responses in animal model

Inovio Biomedical Corporation, a leader in DNA vaccine design, development and delivery, announced today that the company's SynCon™ Chikungunya virus DNA vaccine induced protective neutralizing antibody responses in a preclinical non-human primate model.

18 Nov 2009

Immune System News and Research

Discoveries on anti-HIV antibodies may help researchers create an effective HIV vaccine

Pediatric immunologist receives prestigious annual award from American Philosophical Society

Sugar-coated polymer may offer a new solution for allergy and asthma

GERD is an immune-mediated injury and not the result of acid burn, says new study

H1N1: Bridging the knowledge gap

Adamas Pharmaceuticals expands its Phase 2 TCAD therapy study for influenza A

ISCO, Scripps Research Institute collaborate in study of parthenogenetic stem cells

Exaggerated responses of immune system explain elders’ susceptibility to viral infections

NanoString Technologies to investigate molecular networks with the Broad Institute of MIT and Harvard

Genetic identity of cellular receptor for the immune system's first-response antibody discovered

UNGASS monitoring system provides the overall progress in the global response to HIV

Opiate-based painkillers can increase tumor-cell proliferation, says new study

Protein content of women's saliva changes with advancing age, describe scientists

Results from Phase IIa clinical trial evaluating VT-111 reported by Viron Therapeutics

U.S. health officials testify before Senate Committee about H1N1 vaccine campaign

Patients with recent-onset schizophrenia have raised levels of inflammatory substances

CEL-SCI commences clinical study of LEAPS-H1N1 treatment for hospitalized patients

Researchers identify new way to capture tumor cells in bloodstream; findings can improve early cancer diagnosis

MPI scientists identify mechanism that demonstrates immune cell movement on diverse surfaces

SynCon Chikungunya virus DNA vaccine induces protective neutralizing antibody responses in animal model

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