Respiratory News and Research

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GlaxoSmithKline ready to supply Biota's Relenza to meet CDC recommendations

GlaxoSmithKline (GSK) is prepared to respond to public health needs for Relenza (zanamivir) Inhalation Powder this flu season following a Health Alert Advisory issued by the Centers for Disease Control and Prevention (CDC).

21 Dec 2008

AstraZeneca and MAP Pharmaceuticals announce collaboration on Unit Dose Budesonide

AstraZeneca and MAP Pharmaceuticals, Inc. have announced an exclusive worldwide agreement to develop and commercialize Unit Dose Budesonide (UDB), MAP Pharmaceuticals' proprietary nebulized formulation of budesonide.

21 Dec 2008

Researchers look at processes asbestos fibers use to trigger cancer in human cells

Ohio State University scientists believe they are the first in the world to study the molecular underpinnings of cancer by probing individual bonds between an asbestos fiber and human cells.

18 Dec 2008

More can be done to prevent lung disease in Southeast-Asian babies

A simple, effective and low-cost method of preventing lung disease - and therefore death - in newborn children is not being practiced widely enough in South-East Asian hospitals, according to a major international study involving the University of Adelaide, Australia.

17 Dec 2008

Study to examine how breastfeeding impacts cost of healthcare for very low birth weight babies

The National Institutes of Health (NIH) has awarded nearly $3 million to support Rush University Medical Center's study analyzing how human breast milk impacts the health outcomes and health care cost savings for very low birth weight infants – babies less than 1500 grams.

16 Dec 2008

Natural product from red seaweed brings new antiviral spray

Marinomed Biotechnologie GmbH has been awarded the top prize in the Mercur 2008 innovation awards. This award to Marinomed honours the discovery of antiviral properties in a natural product and the rapid development of the discovery into a nasal spray for treating the common cold.

16 Dec 2008

Allergic rhinitis not associated with snoring or daytime sleepiness

Allergic rhinitis does not appear to be associated with snoring or daytime sleepiness, but individuals with obstructed nasal passages are likely to experience both regardless of whether they have allergies, according to a report in the December issue of Archives of Otolaryngology-Head & Neck Surgery.

15 Dec 2008

Researchers solve failed vaccine mystery

Research led by Johns Hopkins Children's Center scientists has figured out why a respiratory syncytial virus vaccine used in 1966 to inoculate children against the infection instead caused severe respiratory disease and effectively stopped efforts to make a better one.

15 Dec 2008

New research provides a clinical picture of obstructive sleep apnea from over six million hospital admissions

Research in the current issue of the Journal of Clinical Sleep Medicine is the first to show the full clinical picture of comorbid conditions associated with obstructive sleep apnea (OSA), quantify their frequency of occurrence and reveal their possible interrelationships.

15 Dec 2008

Exparel (DepoBupivacaine) shows promise in hernia repair

A Phase II trial of a single intraoperative administration of Exparel (DepoBupivacaine) resulted in significantly reduced pain with activity in the first 8 to 24 hours following surgery, when pain is generally greatest, compared to conventional treatment.

14 Dec 2008

FDA approves Lusedra (fospropofol disodium) injection for monitored anesthesia care sedation

Eisai Corporation of North America today announced that the U.S. Food and Drug Administration (FDA) has approved Lusedra (fospropofol disodium) Injection, an intravenous sedative-hypnotic agent for monitored anesthesia care (MAC) sedation in adult patients undergoing diagnostic or therapeutic procedures.

14 Dec 2008

Potential new avenue for altering lung development in the embryo - will help premature babies

Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have identified a potential new avenue for altering lung development in the embryo which may help to improve the outcome for very premature babies.

14 Dec 2008

FDA to review Barr Pharmaceutical's BLA for adenovirus type 4 and 7 live oral vaccines

Barr Pharmaceuticals, Inc. has announced that the U.S. Food and Drug Administration (FDA) has accepted for review Duramed Pharmaceuticals, Inc.'s Adenovirus Types 4 and 7 Live Oral Vaccines Biologics License Application (BLA).

14 Dec 2008

Australians warned of rabies outbreak in Bali

The warning comes from the head of the Northern Territory's Centre for Disease Control, Dr. Peter Markey, who says anyone bitten or scratched on the island by an animal should seek medical advice; the warning also applies to people who have been to Bali recently.

14 Dec 2008

Novavax announces positive results in trial of seasonal influenza VLP (trivalent) vaccine candidate

Novavax, Inc. has announced favorable results from a Phase IIa human clinical trial of its seasonal influenza VLP (trivalent) vaccine candidate.

12 Dec 2008

AstraZeneca responds to FDA advisory committees' recommendation on SYMBICORT

On December 11, 2008, the Joint Advisory Committees of the U.S. Food and Drug Administration (FDA) - including the Drug Safety & Risk Management Advisory Committee, the Pediatric Advisory Committee, and the Pulmonary-Allergy Drugs Advisory Committee - completed a review of the benefits and risks of asthma medications containing long-acting beta-agonists (LABAs).

12 Dec 2008

RNA interference can facilitate vaccine development

Pharmaceutical companies and universities are racing to develop drugs that use the gene silencing mechanism known as RNA interference to treat a host of diseases.

10 Dec 2008

Carrier screening for spinal muscular atrophy should be offered to all couples

Carrier screening for spinal muscular atrophy (SMA) - a serious genetic disease affecting approximately 1 in 10,000 infants that causes progressive muscle weakness and death - should be made available to all families, according to a new practice guideline issued by the American College of Medical Genetics (ACMG).

10 Dec 2008

DNA vaccine for SARS achieves neutralizing responses in first U.S. human trial

Vical Incorporated (NASDAQ:VICL) today announced that results from a Phase I clinical trial of a DNA vaccine for severe acute respiratory syndrome (SARS), conducted by the National Institutes of Health (NIH) and published in the November 25 issue of Vaccine(1), demonstrated that the vaccine was well-tolerated, and induced neutralizing antibody responses in 80% of the vaccinees and T-cell immune responses in all vaccinees.

10 Dec 2008

AcelRx Pharmaceuticals reports positive results in trial of sublingual Sufentanil NanoTabs in treating post-op pain

AcelRx Pharmaceuticals, Inc. today announced positive results from a Phase 2 clinical study evaluating the safety and efficacy of its lead product candidate, ARX-01, for the treatment of moderate-to-severe inpatient acute pain following knee replacement surgery.

10 Dec 2008

Respiratory News and Research

GlaxoSmithKline ready to supply Biota's Relenza to meet CDC recommendations

AstraZeneca and MAP Pharmaceuticals announce collaboration on Unit Dose Budesonide

Researchers look at processes asbestos fibers use to trigger cancer in human cells

More can be done to prevent lung disease in Southeast-Asian babies

Study to examine how breastfeeding impacts cost of healthcare for very low birth weight babies

Natural product from red seaweed brings new antiviral spray

Allergic rhinitis not associated with snoring or daytime sleepiness

Researchers solve failed vaccine mystery

New research provides a clinical picture of obstructive sleep apnea from over six million hospital admissions

Exparel (DepoBupivacaine) shows promise in hernia repair

FDA approves Lusedra (fospropofol disodium) injection for monitored anesthesia care sedation

Potential new avenue for altering lung development in the embryo - will help premature babies

FDA to review Barr Pharmaceutical's BLA for adenovirus type 4 and 7 live oral vaccines

Australians warned of rabies outbreak in Bali

Novavax announces positive results in trial of seasonal influenza VLP (trivalent) vaccine candidate

AstraZeneca responds to FDA advisory committees' recommendation on SYMBICORT

RNA interference can facilitate vaccine development

Carrier screening for spinal muscular atrophy should be offered to all couples

DNA vaccine for SARS achieves neutralizing responses in first U.S. human trial

AcelRx Pharmaceuticals reports positive results in trial of sublingual Sufentanil NanoTabs in treating post-op pain

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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