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First investigational treatment for infantile-onset SMA shows promising results in clinical trial

A major milestone was reached when nusinersen, an investigational treatment for spinal muscular atrophy (SMA), was shown to significantly improve achievement of motor milestones in babies with infantile-onset SMA, according to an interim analysis of the double-blind, randomized, placebo controlled Phase 3 clinical trial called ENDEAR.

11 Aug 2016

Researchers develop new strategy to convert fibroblasts directly into neuronal cells

Researchers have used CRISPR -- a revolutionary new genetic engineering technique -- to convert cells isolated from mouse connective tissue directly into neuronal cells.

11 Aug 2016

USC researchers discover two Zika proteins potentially responsible for microcephaly

USC researchers have tracked down two Zika proteins potentially responsible for thousands of microcephaly cases in Brazil and elsewhere — taking one small step toward preventing Zika-infected mothers from birthing babies with abnormally small heads.

11 Aug 2016

Antioxidant compound could be effective to combat immune rejection after islet transplantation

A team of researchers has found that doses of bilirubin help provide suppression of the immune response following islet transplantation in mouse models.

11 Aug 2016

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

Immune response measured in tumor biopsies during the course of early treatment predicts which melanoma patients will benefit from specific immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in the journal Cancer Discovery.

11 Aug 2016

New drug provides considerable added benefit in treating adults with advanced renal cell cancer

Nivolumab has been approved since April 2016 as a checkpoint inhibitor for the treatment of adults with advanced renal cell cancer who have already undergone prior therapy.

11 Aug 2016

Drug approved for treatment of vulvovaginal atrophy shows no added benefit in post-menopausal women

Ospemifene (tradename: Senshio) is approved for the treatment of moderate to severe symptomatic vulvovaginal atrophy (VVA) in post-menopausal women who are not candidates for local vaginal oestrogen therapy.

11 Aug 2016

Novel computational analysis of prostate cancer suggests potential targets for therapy

Cancer researchers have applied a comprehensive set of analytical tools to lethal cases of metastatic prostate cancer, yielding a detailed map of the complex networks of interactions among genes and proteins that enable prostate cancer cells to proliferate and evade treatment.

11 Aug 2016

Cutting off fuel to cancer cells may be potential therapeutic strategy for Kras-driven lung cancers

Research from investigators at Rutgers Cancer Institute of New Jersey and Princeton University has identified a new approach to cancer therapy in cutting off a cancer cell's 'fuel supply' by targeting a cellular survival mechanism known as autophagy.

11 Aug 2016

Coordinated treatment for both illnesses could save lives of people with HIV and TB

Tuberculosis (TB) is a leading killer of people with HIV, and providing therapy for both illnesses simultaneously saves lives - according to new guidelines on the treatment of drug-susceptible TB developed jointly by the American Thoracic Society, Centers for Disease Control and Prevention and Infectious Diseases Society of America.

11 Aug 2016

Scientists create stable boron carrier for targeted radiation-based tumour therapies

Targeted radiation-based therapies for treating cancerous tumours such as 'boron neutron capture therapy' (BNCT), rely on the efficient and effective delivery of the capture agent (in this case, boron) to the tumour.

11 Aug 2016

American Urologic Association releases new guidelines for surgical treatment of patients with renal stones

A new guideline for the surgical management of patients with kidney and/or ureteral stones has been released by the American Urologic Association.

10 Aug 2016

Combination of biologic and phototherapy treatment appears to be safe, effective in treating psoriasis

The review, entitled "Combining biologic and phototherapy treatments for psoriasis: safety, efficacy, and patient acceptability," was carried out by a group of researchers in the USA.

10 Aug 2016

Scientists explore neurobiological factors contributing to schizophrenia

Schizophrenic psychoses are a frequently occurring group of psychiatric disorders caused by a combination of biological, social and environmental factors.

10 Aug 2016

New technology uses natural nano-scale lipid transport system to deliver drugs straight to bloodstream

For years scientists and dieticians have argued over the health benefits of dietary fat. Research published this week, however, shows that piggybacking onto natural fat absorption pathways can dramatically enhance the utility of some drugs.

10 Aug 2016

ISCT selects London as host city for 2017 landmark conference to celebrate silver jubilee year

The International Society for Cellular Therapy, the global society of clinicians, researchers, regulatory specialists, technologists, and industry partners dedicated to the translation of cellular therapy into safe and effective therapies to improve patients’ lives, today announces they have awarded London as the host city for the landmark ISCT 2017 Annual Meeting to be held on May 3-6, at ExCeL London Exhibition and Convention Centre, UK to celebrate the Society’s 25th silver jubilee year. More than 1,600 international delegates are expected to attend.

10 Aug 2016

Noninvasive approach using pulsed electric fields may reduce scarring after burn injuries

A Massachusetts General Hospital research team has reported that repeated treatment with pulsed electric fields - a noninvasive procedure that does not generate heat - may help reduce the development of scarring.

10 Aug 2016

Researchers develop machine-learning program that helps identify hundreds of ASD-related genes

Investigators eager to uncover the genetic basis of autism could now have hundreds of promising new leads thanks to a study by Princeton University and Simons Foundation researchers.

9 Aug 2016

New bioinspired device could diagnose formation of blood clots

When in dysfunction, the vascular endothelium -- the tissue that lines the blood vessels throughout our body's entire circulatory system -- plays a big role in the development of many human diseases, including diabetes, stroke, heart disease, viral infections and cancer.

9 Aug 2016

CARRS-Q study shows caffeine combined with bright light can improve driver alertness

Bright light combined with caffeine can improve driving performance and alertness of chronically sleep deprived young drivers, according to a Queensland University of Technology road safety study.

9 Aug 2016

Therapy News and Research

First investigational treatment for infantile-onset SMA shows promising results in clinical trial

Researchers develop new strategy to convert fibroblasts directly into neuronal cells

USC researchers discover two Zika proteins potentially responsible for microcephaly

Antioxidant compound could be effective to combat immune rejection after islet transplantation

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

New drug provides considerable added benefit in treating adults with advanced renal cell cancer

Drug approved for treatment of vulvovaginal atrophy shows no added benefit in post-menopausal women

Novel computational analysis of prostate cancer suggests potential targets for therapy

Cutting off fuel to cancer cells may be potential therapeutic strategy for Kras-driven lung cancers

Coordinated treatment for both illnesses could save lives of people with HIV and TB

Scientists create stable boron carrier for targeted radiation-based tumour therapies

American Urologic Association releases new guidelines for surgical treatment of patients with renal stones

Combination of biologic and phototherapy treatment appears to be safe, effective in treating psoriasis

Scientists explore neurobiological factors contributing to schizophrenia

New technology uses natural nano-scale lipid transport system to deliver drugs straight to bloodstream

ISCT selects London as host city for 2017 landmark conference to celebrate silver jubilee year

Noninvasive approach using pulsed electric fields may reduce scarring after burn injuries

Researchers develop machine-learning program that helps identify hundreds of ASD-related genes

New bioinspired device could diagnose formation of blood clots

CARRS-Q study shows caffeine combined with bright light can improve driver alertness

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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