Clinical Trial News and Research

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Study confirms safety of high and low oxygen levels for cardiac surgery patients

Two out of 10 people who receive cardiac surgery are affected by acute kidney injury, prolonging their hospital stay and increasing their risk for chronic kidney disease, cognitive decline and heart failure.

21 Aug 2024

Study highlights benefits of 20-minute mindful breathing for cancer patients

Twenty minutes of mindful breathing, which focuses a person's attention on their breath, can rapidly reduce the intensity and unpleasantness of cancer pain and relieve the associated anxiety, suggest the findings of a small comparative study, published online in the journal BMJ Supportive & Palliative Care.

20 Aug 2024

Heart-in-a-box technology enhances success of heart transplants

The risk of early heart failure after heart transplantation is lower if the donor heart is stored in a so-called heart-in-a-box instead of in the usual cooler with ice.

20 Aug 2024

Advances in precision medicine enhance cancer immunotherapy

The field of precision medicine, especially in the context of cancer immunotherapy, has seen significant advancements in recent years.

20 Aug 2024

Understanding the benefits and risks of dialysis in older patients with kidney failure

Whether dialysis is the best option for kidney failure and, if so, when to start, may deserve more careful consideration, according to a new study.

19 Aug 2024

Scalable mindfulness programs delivered via telehealth show promise for veterans with chronic pain

Mindfulness-based interventions delivered via telehealth in a scalable format can improve pain and overall well-being among veterans with chronic pain, according to new research published today in JAMA Internal Medicine.

19 Aug 2024

UCSF studies point the way toward continuous care for people with Parkinson's disease

Two new studies from UC San Francisco are pointing the way toward round-the-clock personalized care for people with Parkinson's disease through an implanted device that can treat movement problems during the day and insomnia at night.

19 Aug 2024

Study uncovers oleic acid's role in restoring vaginal microbial balance in bacterial vaginosis

More than half of women globally experience bacterial vaginosis (BV) - an imbalance of naturally occurring microbes in the female genital tract - at least once in their life.

19 Aug 2024

Saliva test offers hope for head and neck cancer patients

But what if a mouthwash-based test to detect biomarkers can help physicians predict disease recurrence in head and neck cancer patients?

16 Aug 2024

Neoadjuvant immunotherapy yields comparable outcomes in high-risk liver cancer surgery

Patients with liver cancer who received immune checkpoint inhibitors (ICIs) before surgery - including those who would not have been eligible for surgery by conventional criteria - had similar outcomes to patients who received surgery upfront, according to results from a retrospective study.

15 Aug 2024

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Researchers at Children's Hospital of Philadelphia (CHOP), St. Jude Children's Research Hospital (St. Jude) and the Children's Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by genetic changes in non-coding portions of our DNA.

14 Aug 2024

Breakthrough malaria vaccine offers long-term protection for pregnant women

In a report published in The Lancet Infectious Diseases (Safety and efficacy of PfSPZ Vaccine against malaria in healthy adults and women anticipating pregnancy in Mali: two randomized, double-blind, placebo-controlled, phase 1 and 2 trials) a team led by investigators at the Malaria Research and Training Center (MRTC), Bamako, Mali; the Laboratory of Malaria Immunology and Vaccinology (LMIV), National Institute of Allergy and Infectious Diseases, National Institutes of Health; and Sanaria Inc. describes the durable protective efficacy against malaria shown by Sanaria® PfSPZ Vaccine when administered to women prior to pregnancy.

14 Aug 2024

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

University Hospitals (UH) Seidman Cancer Center hematologist-oncologist Leland Metheny, MD, is leading the trial.

14 Aug 2024

KERI advances neuromodulation technology for appetite suppression in obesity treatment

The R&D on neuromodulation technology for the treatment and management of metabolic syndrome conducted by a team led by Dr. Ki-young Shin of Human Care Electro-Medical Device Research Center, Electro-Medical Equipment Research Division of KERI is underway smoothly.

14 Aug 2024

Study finds minimal impact of cesarean antibiotics on infant gut microbiome

Cesarean section recipients are usually given prophylactic antibiotics just before the procedure to prevent later infections at the surgical site.

14 Aug 2024

Study reveals how salt-based nicotine and menthol flavors influence e-cigarette use in young adults

Study found that salt-based nicotine and menthol flavoring in e-cigarettes significantly increase nicotine levels and positive experiences among young adults, potentially heightening addiction risks.

14 Aug 2024

Nanoparticles offer new hope for treating red meat allergies linked to tick bites

Nanoparticles delivered intravenously in mice can block the allergic reactions to red meat caused by the bite of the lone star tick, new research led by the University of Michigan shows.

13 Aug 2024

Two studies uncover how immunotherapies work together to activate immune responses in melanoma

Two studies published in the latest issue of the journal Cell by University of Pittsburgh researchers uncover how immunotherapies targeting the immune checkpoints PD1 and LAG3 work together to activate immune responses.

13 Aug 2024

NCI awards $3.1 million to support new mental health model for cancer patients

Depression is common among people with likely incurable cancer – understandably so. But studies have shown that it can be treated, and if the goal is for individuals to be able to engage as much as possible with family, friends, hobbies or whatever gives them joy and purpose in whatever amount of time they have, then treating depression becomes imperative.

13 Aug 2024

KERI's transcranial random noise stimulation shows promise for metabolic syndrome treatment

12 Aug 2024

Clinical Trial News and Research

Study confirms safety of high and low oxygen levels for cardiac surgery patients

Study highlights benefits of 20-minute mindful breathing for cancer patients

Heart-in-a-box technology enhances success of heart transplants

Advances in precision medicine enhance cancer immunotherapy

Understanding the benefits and risks of dialysis in older patients with kidney failure

Scalable mindfulness programs delivered via telehealth show promise for veterans with chronic pain

UCSF studies point the way toward continuous care for people with Parkinson's disease

Study uncovers oleic acid's role in restoring vaginal microbial balance in bacterial vaginosis

Saliva test offers hope for head and neck cancer patients

Neoadjuvant immunotherapy yields comparable outcomes in high-risk liver cancer surgery

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Breakthrough malaria vaccine offers long-term protection for pregnant women

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

KERI advances neuromodulation technology for appetite suppression in obesity treatment

Study finds minimal impact of cesarean antibiotics on infant gut microbiome

Study reveals how salt-based nicotine and menthol flavors influence e-cigarette use in young adults

Nanoparticles offer new hope for treating red meat allergies linked to tick bites

Two studies uncover how immunotherapies work together to activate immune responses in melanoma

NCI awards $3.1 million to support new mental health model for cancer patients

KERI's transcranial random noise stimulation shows promise for metabolic syndrome treatment

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