Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Primary cilium's GPS-like cell structure crucial to wound repair

The primary cilium, the solitary, antenna-like structure that studs the outer surfaces of virtually all human cells, orient cells to move in the right direction and at the speed needed to heal wounds, much like a Global Positioning System helps ships navigate to their destinations.

17 Dec 2008

Phosphorus binders help dialysis patients

For patients on dialysis, taking medications to reduce levels of the mineral phosphorus in the blood may reduce the risk of death by 25 to 30 percent, reports a study in the Journal of the American Society of Nephrology (JASN).

17 Dec 2008

Relationship of dialysis modality and mortality

For kidney disease patients who need to undergo dialysis, one type of treatment is not best for all, according to a study appearing in the January 2009 issue of the Journal of the American Society Nephrology (JASN).

17 Dec 2008

High phosphorus levels in blood linked to coronary calcification in chronic kidney disease

For patients with moderate chronic kidney disease (CKD), higher levels of phosphorus in the blood are associated with increased calcification of the major arteries and heart valves - which may contribute to the increased risk of cardiovascular disease in patients with CKD, reports a study in the Journal of the American Society of Nephrology (JASN).

10 Dec 2008

Rosiglitazone shows potential for treating focal segmental glomerulosclerosis

The antidiabetes drug rosiglitazone may have the potential to protect kidney function in patients with a condition called focal segmental glomerulosclerosis (FSGS), according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN).

10 Dec 2008

Thiamine reverses early diabetic kidney disease

Researchers at the University of Warwick have discovered high doses of thiamine - vitamin B1 - can reverse the onset of early diabetic kidney disease.

8 Dec 2008

Kidney disease patients with poor health literacy are less likely to receive kidney transplants

Kidney disease patients' ability to understand basic health information may have a significant impact on whether or not they will receive an organ transplant, according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology.

3 Dec 2008

Poor quality HDL cholesterol bad for you

If you think your levels of "good cholesterol" are good enough, a new study published in the December 2008 issue of The FASEB Journal suggests that you may want to think again.

1 Dec 2008

Potential gene target for treatment of common hearing, vertigo and balance problems

A UCLA study shows for the first time how microscopic crystals form sound and gravity sensors inside the inner ear.

30 Nov 2008

Study compares strategies for BK virus nephropathy

For kidney transplant recipients with a serious complication called BK virus-associated nephropathy (BKVAN), promptly cutting back on anti-rejection drugs reduces the risk of losing the kidney (graft loss), according to a report in the November Clinical Journal of the American Society of Nephrology (CJASN).

26 Nov 2008

Study examines medical cost increases for individuals living with diabetes

People diagnosed with diabetes spend over $4,100 more each year on medical costs than people who don't have diabetes, a gap that increases substantially each year following the initial diagnosis, according to a study published online today in the journal Diabetes Care.

25 Nov 2008

Follow up results from first case of pulmonary hypertension treated with stem cells

Dr. Leonel Fernandez Liriano, Professor of Medicine at Pontifical Catholic University School of Medicine (PCUSM), announced nine month follow up results for the first patient treated with engineered stem cells in a clinical study of primary pulmonary hypertension.

25 Nov 2008

World's first pediatric robotic bladder reconstruction performed

A 10-year-old Chicago girl born with an abnormally small bladder that made her incontinent has become the first patient to benefit from a new robotic-assisted bladder-reconstruction method developed by surgeons at the University of Chicago Medical Center.

20 Nov 2008

Helping diabetics through the holiday season

November ushers in American Diabetes Month - not only a time to be thankful for bustling basic and clinical research underway on the disease, but also the unofficial start of the holiday season.

20 Nov 2008

Acute kidney injury predisposes elderly to serious kidney disease

Acute kidney injury (AKI) - which is often caused by trauma, illness, or surgery - predisposes elderly individuals to the most serious form of chronic kidney disease (CKD), known as end stage renal disease (ESRD), according to a study appearing in the January 2009 issue of the Journal of the American Society Nephrology (JASN).

19 Nov 2008

Hypertension may develop undetected in young African-American men

Young and healthy African-American men have higher central blood pressure and their blood vessels are stiffer compared to their white counterparts, signs that the African American men are developing hypertension early and with little outward sign, according to a new study.

17 Nov 2008

Higher levels of blood phosphate may be a previously unidentified and modifiable cardiovascular risk factor

Healthy adults with higher levels of phosphate in the blood are more likely to have increased levels of calcium in the coronary arteries-a key indicator of atherosclerosis and future cardiovascular disease risk, reports a study in the February 2009 issue of the Journal of the American Society of Nephrology (JASN).

16 Nov 2008