immunity News and Research

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Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs.

9 Mar 2023

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Researchers identified that individuals with a deficiency of myeloid differentiation primary response 88 (MyD88) and interleukin-1 receptor-associated kinase 4 (IRAK-4) due to an autosomal recessive condition were highly susceptible to developing hypoxemic coronavirus disease 2019 (COVID-19) pneumonia when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Mar 2023

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

Researchers assessed the impact of an anti-CD3 monoclonal antibody called Foralumab in COVID-19 treatment.

9 Mar 2023

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Researchers assessed the role of ACE2 in the COVID-19 pandemic.

9 Mar 2023

Evolutionary convergence of the SARS-CoV-2 A-lineage spike sequences

Researchers assessed the impact of evolutionary convergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) A-lineage (Clade 19B) spike sequences on B-lineage viral replication.

9 Mar 2023

Microglia partner with T cells to cause neurodegeneration, study shows

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.

8 Mar 2023

Review on factors related to variations in human microbiota

In a recent review published in Current Opinion in Microbiology, researchers reviewed existing data on variations in human microbiota, emphasizing on ageing- and ethnicity-associated changes in the microbiota.

8 Mar 2023

Connection between mitochondrial metabolite and activation of inflammatory response revealed

A new study shows for the first time a connection between a mitochondrial metabolite and the activation of an inflammatory response.

8 Mar 2023

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Mass General researchers have discovered a novel molecular mechanism responsible for the most common forms of acquired hydrocephalus, potentially opening the door to the first-ever nonsurgical treatment for a life-threatening disease that affects about a million Americans.

8 Mar 2023

Denosumab may benefit postmenopausal patients with hormone receptor-negative breast tumors and RANK protein expression

The drug denosumab is currently used to treat osteoporosis and bone metastases. For more than a decade, its potential therapeutic benefit in the treatment of breast cancer has also been studied.

7 Mar 2023

Symptomatic COVID-19 is associated with deficits in task-related cognitive function and psychiatric symptoms

Researchers conducted a prospective population survey, functional brain imaging, and a cognitive task performance test to determine whether a history of symptomatic coronavirus disease 2019 (COVID-19) was associated with psychiatric and neurocognitive symptoms.

7 Mar 2023

Effectiveness of monovalent COVID-19 mRNA booster vaccination vs. two-dose primary series during Omicron variant circulation

Researchers estimated the immune protection conferred by monovalent-type COVID-19 mRNA booster doses vs. two-dose prime vaccination series during SARS-CoV-2 Omicron variant predominance in community settings.

7 Mar 2023

CDC recommendations and clinical considerations for the treatment of severe Mpox

In a recent article published in the United States (U.S.) Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report, a team of researchers discussed the medical countermeasures and clinical considerations for treating severe manifestations of Mpox.

6 Mar 2023

Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses

Researchers evaluate the response of pre-existing immunity to booster doses of mRNA COVID-19 vaccines.

6 Mar 2023

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

The influenza season marks the beginning of a time of illness, sometimes serious or even fatal, in much of the world. For this reason, flu shots are recommended, especially for individuals with underlying diseases such as chronic hepatitis B (CHB) infection, since they are at higher risk for adverse outcomes.

6 Mar 2023

immunity News and Research

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Evolutionary convergence of the SARS-CoV-2 A-lineage spike sequences

Microglia partner with T cells to cause neurodegeneration, study shows

Review on factors related to variations in human microbiota

Connection between mitochondrial metabolite and activation of inflammatory response revealed

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Denosumab may benefit postmenopausal patients with hormone receptor-negative breast tumors and RANK protein expression

Symptomatic COVID-19 is associated with deficits in task-related cognitive function and psychiatric symptoms

Effectiveness of monovalent COVID-19 mRNA booster vaccination vs. two-dose primary series during Omicron variant circulation

CDC recommendations and clinical considerations for the treatment of severe Mpox

Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Brain development in autistic Individuals differs from people with typical neurodevelopment, study confirms

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Age-associated B cells found to be important drivers of lupus

Large-scale longitudinal study of neutralizing antibody responses to norovirus in children

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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