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People with PTSD appear to suffer from disrupted context processing, say researchers

For decades, neuroscientists and physicians have tried to get to the bottom of the age-old mystery of post-traumatic stress disorder, to explain why only some people are vulnerable and why they experience so many symptoms and so much disability.

7 Oct 2016

Researchers explain why explain why some tumors recur after immunotherapy

Immunotherapy is a new and highly promising form of treatment for cancer. In many patients, however, tumors recur after immunotherapy.

7 Oct 2016

Added benefit not proven for melanoma drug, IQWiG finds

Talimogene laherparepvec has been approved since December 2015 for adults with advanced melanoma.

7 Oct 2016

No added benefit proven for pulmonary arterial hypertension drug, IQWiG finds

Selexipag is approved for long-term treatment of pulmonary arterial hypertension (PAH) in adults with moderate to severe symptoms.

7 Oct 2016

Survey reveals inequalities in access to new, life saving drugs for melanoma in Europe

Over 5000 patients with metastatic melanoma in Europe are denied access to new, life saving drugs every year, according to a survey presented at the ESMO 2016 Congress in Copenhagen.

7 Oct 2016

New study of Phase II Alzheimer's drug pipeline reveals more ways to combat disease

A new analysis of the Phase II Alzheimer's drug pipeline, conducted by ResearchersAgainstAlzheimer's, revealed 57 new Alzheimer's drugs. According to the analysis, nearly twice as many mechanisms of action are being tested in Phase II than in Phase III clinical trials.

7 Oct 2016

Researchers to explore potential roles of tumor-suppressor gene in kidney cancer

Renal cell carcinoma is the most common type of kidney cancer, and African-Americans and males appear most at risk for this disease that can be asymptomatic until it has spread and become highly lethal, said Dr. Vinata B. Lokeshwar, cancer researcher and chair of the Department of Biochemistry and Molecular Biology at the Medical College of Georgia at Augusta University.

7 Oct 2016

Researchers report high response rate with single drug in phase I/II trial of paediatric brain cancer

A high response rate with a single drug in a phase I/II trial of paediatric brain tumour has set the stage for combination therapy with higher response and lower toxicity, researchers reported at the ESMO 2016 Congress in Copenhagen.

7 Oct 2016

New program at Seattle Children's Hospital helps kids find freedom from OCD

Since Eva Tomassini was 4 years old, she remembers her life being controlled by rules. Not from her parents, or school, but rules she created in her head, like having to arrange things in a certain way or run away in order to prevent terrible things from happening.

7 Oct 2016

Study offers promise for therapeutic management of fetal and congenital genetic diseases in utero

A breakthrough study by research teams at Rosalind Franklin University of Medicine and Science and Oregon Health & Science University offers promise for therapeutic management of congenital diseases in utero using designer nucleotide sequences that can simply be injected into the fluid surrounding the developing fetus to potentially treat disabling-to-lethal genetic defects.

7 Oct 2016

Aggressive neuroblastoma contains specific protein not found in benign forms of cancer

Aggressive forms of neuroblastoma contain a specific protein in their cells' nuclei that is not found in the nuclei of more benign forms of the cancer, and the discovery, made through research from the University of Rochester Medical Center, could lead to new forms of targeted therapy.

6 Oct 2016

Combination therapy for melanoma has added benefit in certain patients

Nivolumab in combination with ipilimumab has been approved since May 2016 for adults with advanced melanoma. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this drug offers an added benefit.

6 Oct 2016

Juvenile offenders with PTSD at greater risk of entering substance abuse treatment, study finds

Juvenile offenders who have a diagnosis of post-traumatic stress disorder are at 67 percent greater risk of entering substance abuse treatment within seven years, a new study found.

6 Oct 2016

RTI extends research support to improve treatment for pelvic floor disorders in women

RTI International will continue supporting research efforts to improve clinical care for women with pelvic floor disorders as part of the Pelvic Floor Disorders Network.

6 Oct 2016

Siemens announces FDA 510(k) clearance for Xprecia Stride Coagulation Analyzer

Siemens Healthineers has more than 30 years of central lab hemostasis leadership. Building on to its portfolio, the company announced today FDA 510(k) clearance for a hand-held portable coagulation analyzer.

From Siemens Healthineers Point of Care Diagnostics 6 Oct 2016

Increasing incidence of thyroid cancer in past three decades

The incidence of thyroid cancer has tripled in the past three decades, yet the reason for this is not clear.

6 Oct 2016

Hard-to-control asthma in children has significant baseline features, study finds

Bronchodilator responsiveness, nasal inflammation and allergy were among the most significant baseline features that distinguished hard-to-control asthma in inner-city children and adolescents.

6 Oct 2016

Frailty screening could help improve outcomes in older surgery patients

Identifying frailty in older patients could increase their chances of surviving surgery, as well as improve their overall outcomes, according to a new study posted online today in The Annals of Thoracic Surgery.

6 Oct 2016

C-11 choline PET and MRI help physicians map patterns of prostate cancer recurrence after surgery

A team of Mayo Clinic researchers has, for the first time, successfully mapped patterns of prostate cancer recurrence, following surgery. Using C-11 choline PET imaging and multiparametric MRI, researchers found an anatomically diverse pattern of recurrence, which may help optimize treatment of patients whose prostate cancer returns after surgery.

6 Oct 2016

Review examines link between insomnia and alcohol dependence

Individuals with alcohol dependence (AD) often have sleep-related disorders such as insomnia, circadian-rhythm sleep disorders, breathing-related sleep disorders, movement disorders, and parasomnias such as sleep-related eating disorder, sleepwalking, nightmares, sleep paralysis, and REM sleep behavior disorder.

5 Oct 2016

Therapy News and Research

People with PTSD appear to suffer from disrupted context processing, say researchers

Researchers explain why explain why some tumors recur after immunotherapy

Added benefit not proven for melanoma drug, IQWiG finds

No added benefit proven for pulmonary arterial hypertension drug, IQWiG finds

Survey reveals inequalities in access to new, life saving drugs for melanoma in Europe

New study of Phase II Alzheimer's drug pipeline reveals more ways to combat disease

Researchers to explore potential roles of tumor-suppressor gene in kidney cancer

Researchers report high response rate with single drug in phase I/II trial of paediatric brain cancer

New program at Seattle Children's Hospital helps kids find freedom from OCD

Study offers promise for therapeutic management of fetal and congenital genetic diseases in utero

Aggressive neuroblastoma contains specific protein not found in benign forms of cancer

Combination therapy for melanoma has added benefit in certain patients

Juvenile offenders with PTSD at greater risk of entering substance abuse treatment, study finds

RTI extends research support to improve treatment for pelvic floor disorders in women

Siemens announces FDA 510(k) clearance for Xprecia Stride Coagulation Analyzer

Increasing incidence of thyroid cancer in past three decades

Hard-to-control asthma in children has significant baseline features, study finds

Frailty screening could help improve outcomes in older surgery patients

C-11 choline PET and MRI help physicians map patterns of prostate cancer recurrence after surgery

Review examines link between insomnia and alcohol dependence

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