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Combinational analysis of FISH and IHC detects NSCLC patients with rare ALK fusions

The combined use of fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) identified non-small cell lung cancer (NSCLC) patients with rare or novel anaplastic lymphoma kinase (ALK) gene rearrangements, not otherwise identified by FISH alone, that showed response to crizotinib treatment.

12 Sep 2016

Psychotropic drugs cannot alleviate symptoms of mental disorders, say researchers

Drugs don't lead to sustainable alleviation of mental disorders, as the psychologists Prof Dr Jürgen Margraf and Prof Dr Silvia Schneider claim in a commentary published in "EMBO Molecular Medicine".

12 Sep 2016

Learning to downregulate amygdala activity could help gain control of emotional responses

Training the brain to treat itself is a promising therapy for traumatic stress. The training uses an auditory or visual signal that corresponds to the activity of a particular brain region, called neurofeedback, which can guide people to regulate their own brain activity.

12 Sep 2016

Research reveals how Zika virus arrests fetal brain development in pigtail macaque

For the first time, abnormal brain development following a Zika infection during pregnancy has been documented experimentally in the offspring of a non-human primate.

12 Sep 2016

Using the immune system to fight cancer: an interview with Dr Charles Akle

We all produce as many as 100,000 different types of cancer cells every day, which are recognized and eliminated by our extraordinarily efficient immune system. However, if something goes wrong with the immune system, and it no longer gets rid of these cells, then that’s when cancerous cells grow and become a problem.

12 Sep 2016

Scientists use insect model to reveal therapeutic potential of C. difficile bacteriophages

University of Leicester scientists have previously identified the potential of using a bacteriophage cocktail to eradicate Clostridium difficile infection (CDI) and in this research, using an insect model, they show that their prophylactic use can prevent infection forming in the first place.

12 Sep 2016

Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

In a novel controlled clinical trial, participants in a six-day Ayurvedic-based well-being program that featured a vegetarian diet, meditation, yoga and massages experienced measurable decreases in a set of blood-based metabolites associated with inflammation, cardiovascular disease risk and cholesterol regulation.

9 Sep 2016

Experts develop urine-based method to diagnose conditions in newborn babies

Experts from the V. I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology and the Moscow Institute of Physics and Technology have devised a method that uses the urinary proteome to diagnose conditions in newborn babies.

9 Sep 2016

Study opens door to new class of therapies for Ras-dependent cancers

New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapies.

9 Sep 2016

New treatment reduces activity of Huntington's disease gene for several months in mice

A single injection of a new treatment has reduced the activity of the gene responsible for Huntington's disease for several months in a trial in mice.

9 Sep 2016

Liquid biopsies may be effective option for detecting mutations in advanced lung cancer patients

For patients with advanced lung cancer, a non-invasive liquid biopsy may be a more effective and suitable alternative to the gold standard tissue biopsy to detect clinically relevant mutations and help guide their course of treatment, suggests a new study published this week in the journal Clinical Cancer Research from researchers at the Abramson Cancer Center at the University of Pennsylvania.

9 Sep 2016

UTHealth receives DOD award to investigate stem cell therapy in adults with TBI

A research team led by Charles S. Cox, Jr., M.D., at The University of Texas Health Science Center at Houston has been awarded $6.8 million from the U.S. Department of Defense to assess the safety and efficacy of using autologous stem cell therapy in adults with emergent traumatic brain injury.

9 Sep 2016

Viral vector-based approaches could improve effectiveness of CFTR gene therapy

Cystic fibrosis (CF) is characterized by accumulation of thick mucus in the lungs and is associated with a high incidence of bacterial infection. Mutations in the gene encoding CF transmembrane conductance regulator (CFTR) underlie the disease.

9 Sep 2016

Researchers identify higher risk of early chemotherapy-related death in older patients with DLBCL

Although diffuse large B-cell lymphoma (DLBCL) is a curable disease in most patients aged 65 years or older, these patients are also at higher risk of chemotherapy-related death within the first 30 days of treatment.

9 Sep 2016

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

In research published online today in Science, a team of scientists describe a new therapeutic strategy to target a hidden Achilles' heel shared by all known types of Ebola virus.

8 Sep 2016

Researchers reveal potential therapeutic treatment for alphavirus infections

Research conducted by Griffith University and Melbourne-based company Paradigm Biopharmaceuticals Limited has uncovered a potential new therapeutic treatment for the global battle against mosquito-borne alphavirus infections, including the debilitating Ross River Virus (RRV) and Chikungunya Virus (CHIKV).

8 Sep 2016

Animal-assisted therapy can help students combat homesickness, study shows

The expression dog is man's best friend might have more weight in the case of first-year university students suffering from homesickness, according to a new UBC study.

8 Sep 2016

AAGBI releases new standards of monitoring during anaesthesia for better patient safety

The Association of Anaesthetists of Great Britain and Ireland has this month published new Standards in patient monitoring (Recommendations for standards of monitoring during anaesthesia and recovering 2016), and calls for all hospitals to work towards using capnography for all anaesthetist-led sedation to improve patient safety.

8 Sep 2016

New study reveals benefits of home non-invasive ventilation in improving lives of COPD patients

Today ResMed welcomed positive results from the independent Home Oxygen Therapy- Home Mechanical Ventilation (HOT-HMV) study regarding the benefits of home non-invasive ventilation (NIV).

From ResMed Corp 8 Sep 2016

Experimental drug shows promise for stopping melanoma and other forms of cancer

An experimental cancer drug works differently than intended and shows significant promise for stopping melanoma and possibly other forms of cancer, research from the University of Virginia School of Medicine suggests.

7 Sep 2016

Therapy News and Research

Combinational analysis of FISH and IHC detects NSCLC patients with rare ALK fusions

Psychotropic drugs cannot alleviate symptoms of mental disorders, say researchers

Learning to downregulate amygdala activity could help gain control of emotional responses

Research reveals how Zika virus arrests fetal brain development in pigtail macaque

Using the immune system to fight cancer: an interview with Dr Charles Akle

Scientists use insect model to reveal therapeutic potential of C. difficile bacteriophages

Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

Experts develop urine-based method to diagnose conditions in newborn babies

Study opens door to new class of therapies for Ras-dependent cancers

New treatment reduces activity of Huntington's disease gene for several months in mice

Liquid biopsies may be effective option for detecting mutations in advanced lung cancer patients

UTHealth receives DOD award to investigate stem cell therapy in adults with TBI

Viral vector-based approaches could improve effectiveness of CFTR gene therapy

Researchers identify higher risk of early chemotherapy-related death in older patients with DLBCL

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

Researchers reveal potential therapeutic treatment for alphavirus infections

Animal-assisted therapy can help students combat homesickness, study shows

AAGBI releases new standards of monitoring during anaesthesia for better patient safety

New study reveals benefits of home non-invasive ventilation in improving lives of COPD patients

Experimental drug shows promise for stopping melanoma and other forms of cancer

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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