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Study shows twice daily exercise intervention improves bone strength in VLBW pre-term infants

Because of their low weight and premature birth, very low birth weight (VLBW) pre-term infants have lower bone mineral mass and a greater need for bone nutrients compared to most new-born infants.

7 Jul 2016

New book provides more insight into diagnosis and research of hereditary hearing loss

Genetics of Deafness offers a journey through areas crucial for understanding the causes and effects of hearing loss.

7 Jul 2016

Inherited mutations in DNA repair genes may predispose to metastatic prostate cancer

Inherited mutations in genes that function to repair DNA may contribute to metastatic prostate cancer more than previously recognized, according to a study out today in the New England Journal of Medicine.

7 Jul 2016

New microfluidic device allows scientists to use safe electric fields to treat cancer

Researchers at MIT's research center in Singapore have developed a new microfluidic device that tests the effects of electric fields on cancer cells.

7 Jul 2016

IQWiG study: HBOT shows neither hint of benefit nor of harm in people with diabetic foot

If people with a diabetic foot syndrome (DFS) receive hyperbaric oxygen therapy (HBOT) in addition to conventional treatment, this can promote wound healing. However, the certainty of conclusions of the available study results is restricted.

6 Jul 2016

Existing anti-inflammatory drugs may be effective in treating epilepsy

In epileptic patients, seizures lead to an increased level of inflammation-related proteins called chemokines in the brain, and systemic inflammation likely helps trigger and promote the recurrence of seizures, making inflammation a promising new target for anticonvulsant therapy.

6 Jul 2016

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

When Amy Sweat was 19 years old, while she was in the hospital recovering from surgery, she was diagnosed with Type 2 diabetes. Ms. Sweat was treated for her diabetes, first on oral drugs, then on increasingly larger doses of insulin, but the years went by and she never was able to achieve good blood sugar control.

6 Jul 2016

Added benefit of idelalisib drug not proven for patients with CLL

Already in 2014, the German Institute for Quality and Efficiency in Health Care examined in an early benefit assessment whether idelalisib offers advantages over the appropriate comparator therapy for patients with chronic lymphocytic leukaemia (CLL).

6 Jul 2016

Phase 1 trial to examine efficacy of promising malaria vaccine in Burkina Faso

Malaria is one of the world's deadliest diseases: it infects hundreds of millions of people every year, and kills about half a million, most of them under five years of age.

6 Jul 2016

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Precise predictions of whether a tumor is likely to spread would help clinicians and patients choose the best course of treatment. But current methods fall short of the precision needed.

6 Jul 2016

Menopause symptoms: can a healthcare professional help? An interview with Dr Heather Currie

The survey showed that only 50% of women consulted a healthcare professional about their symptoms, despite the fact that many women said their symptoms were having a significant effect on their work life, social life, home life and sex life.

6 Jul 2016

New lung-targeted gene therapy shows promise in improving treatment for emphysema

Researchers have developed a new strategy using lung-targeted gene therapy that may lead to improved treatments for inherited diseases including emphysema.

6 Jul 2016

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

Self-monitoring or self-management of anticoagulation therapy can help reduce thromboembolic events

Patients on long-term anticoagulation therapy who test their own blood-clotting time from home and continue to be managed by their GP are significantly less likely to experience a thromboembolic event, according to Oxford University researchers.

6 Jul 2016

JACC publishes pivotal data on Tryton’s dedicated coronary bifurcation stent, results submitted to FDA

Tryton Medical, Inc., the leading developer of stents designed to treat coronary bifurcation lesions, today announced that results from the Tryton Confirmatory Study of the company’s Side Branch Stent have been published in JACC Cardiovascular Interventions.

6 Jul 2016

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses.

6 Jul 2016

Quantum Genomics initiates Phase IIa trial for heart failure

Quantum Genomics, a biopharmaceutical company with the mission of developing new therapies for unmet medical needs in the field of cardiovascular diseases, today announced the initiation of its Phase IIa multicentric clinical trial of GQC101, entitled QUID HF (QUantum Genomics Incremental Dosing in Heart Failure), for the treatment of patients with chronic heart failure. The first three clinical centres of the European trial have been opened in France and Norway.

6 Jul 2016

Necitumumab drug shows minor added benefit in patients with metastatic NSCLC

The monoclonal antibody necitumumab has been approved since February 2016 for the treatment of patients with locally advanced or metastatic epidermal growth factor receptor (EGFR) expressing non-small cell lung cancer (NSCLC) who have not received prior chemotherapy for this condition.

5 Jul 2016

Ticagrelor drug shows minor added benefit for patients with history of myocardial infarction

The German Institute for Quality and Efficiency in Health Care assessed the added benefit of ticagrelor for patients with acute coronary syndrome already in 2011 in its very first dossier assessment, just after the Act on the Reform of the Market for Medicinal Products had come into force.

5 Jul 2016

FDA approves Absorb GT1 BVS to treat coronary artery disease

The U.S. Food and Drug Administration today approved the first fully absorbable stent to treat coronary artery disease.

5 Jul 2016

Therapy News and Research

Study shows twice daily exercise intervention improves bone strength in VLBW pre-term infants

New book provides more insight into diagnosis and research of hereditary hearing loss

Inherited mutations in DNA repair genes may predispose to metastatic prostate cancer

New microfluidic device allows scientists to use safe electric fields to treat cancer

IQWiG study: HBOT shows neither hint of benefit nor of harm in people with diabetic foot

Existing anti-inflammatory drugs may be effective in treating epilepsy

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

Added benefit of idelalisib drug not proven for patients with CLL

Phase 1 trial to examine efficacy of promising malaria vaccine in Burkina Faso

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Menopause symptoms: can a healthcare professional help? An interview with Dr Heather Currie

New lung-targeted gene therapy shows promise in improving treatment for emphysema

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Self-monitoring or self-management of anticoagulation therapy can help reduce thromboembolic events

JACC publishes pivotal data on Tryton’s dedicated coronary bifurcation stent, results submitted to FDA

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Quantum Genomics initiates Phase IIa trial for heart failure

Necitumumab drug shows minor added benefit in patients with metastatic NSCLC

Ticagrelor drug shows minor added benefit for patients with history of myocardial infarction

FDA approves Absorb GT1 BVS to treat coronary artery disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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