B Cell News and Research

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Exploring the link between microbial balance and aging mechanisms

Aging is a multifaceted process driven by interconnected biological mechanisms, among which genomic instability and telomere attrition stand as primary hallmarks.

20 May 2025

Cell Painting technology uncovers flavonoids with potential to treat bladder cancer

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

20 May 2025

Study reveals dual role of TEAD proteins in neural development

Scientists at St. Jude Children’s Research Hospital found that, in neural development, the same set of proteins involved in cellular self-renewal can also facilitate differentiation with the right binding partner.

20 May 2025

New discovery may help explain why some people infected with CHIKV develop severe joint pain

Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has been identified in more than 110 countries around the world. The virus typically causes flu-like symptoms, but it can also trigger chronic, severe joint pain in some people.

20 May 2025

Finnish researchers uncover how to optimize bexmarilimab use in cancer care

Researchers at the University of Turku, Finland, have taken a step towards more personalized and effective cancer treatments.

20 May 2025

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Researchers have used a personalised base-editing gene therapy to successfully treat an infant with carbamoyl-phosphate synthetase 1 (CPS1) deficiency, a rare and life-threatening inborn error of metabolism. This pioneering approach chemically corrects the underlying mutation without cutting DNA, showing promise for precision treatment of ultrarare genetic disorders.

20 May 2025

Genetic variations in Prader-Willi syndrome offer key insights into autism and psychosis

In a comprehensive Genomic Press Invited Expert Review, researchers from the University of Haifa have synthesized cutting-edge findings on Prader-Willi syndrome (PWS), revealing how this complex neurodevelopmental disorder serves as a critical model for understanding the interplay between autism spectrum disorder (ASD) and psychotic spectrum disorders (PSD).

20 May 2025

Age-related immune decline reduces CAR-T cell therapy efficacy

As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells.

20 May 2025

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the commonest cancer in childhood and one that can be particularly difficult to treat in older patients, according to Cambridge scientists.

20 May 2025

MIT researchers discover new potential drug targets for Alzheimer’s disease

By combining information from many large datasets, MIT researchers have identified several new potential targets for treating or preventing Alzheimer's disease.

20 May 2025

Diabetes drug shows potential in slowing prostate cancer progression

A drug used to treat type 2 diabetes may also be effective in slowing the progression of prostate cancer.

20 May 2025

Air pollution fuels artery damage and accelerates heart disease, review finds

Researchers reviewed how air pollution, especially fine particulate matter (PM2.5), drives the development and worsening of atherosclerosis, a leading cause of heart attacks and strokes. Their findings highlight robust links between air pollution exposure, early artery changes, and underlying biological mechanisms fueling cardiovascular risk.

19 May 2025

Including dessert in diet plans helps reduce cravings and maintain weight loss

Food cravings are the downfall of many dieters, who feel locked in an eternal battle with their willpower to resist the tempting sweets, snacks and other foods they love.

19 May 2025

Sucralose disrupts male fertility by damaging sperm and altering hormones in animal study

Researchers found that chronic sucralose exposure in male rats disrupted reproductive hormones, damaged sperm, and impaired testicular function through oxidative stress and autophagy dysregulation. These findings raise concerns about the reproductive risks of high sucralose intake and its persistent presence in the environment.

19 May 2025

Breakthrough microimager offers new possibilities for internal imaging

Researchers have developed an extremely thin, flexible imager that could be useful for noninvasively acquiring images from inside the body. The new technology could one day enable early and precise disease detection, providing critical insights to guide timely and effective treatment.

19 May 2025

What makes H5N1 a pandemic risk and how can we stop it?

A new PEARLS article in PLoS Pathogens reviews the rapid evolution and pandemic potential of emerging influenza A viruses, with a focus on H5N1. It highlights scientific advances and future strategies to outpace the virus, from next-generation vaccines to AI-driven antiviral discovery.

19 May 2025

Ground-breaking discovery reveals common master switch for brain-related diseases

The 21st edition of Sustainability Through Science and Technology Summit 2025 (SIPS 2025), dedicated to Prof. Aaron Ciechanover, Nobel Laureate in Chemistry, to be held in Cebu, Philippines, from 17-20 November 2025, has confirmed the participation of Davis Joseph as an invited summit plenary lecturer for his recent ground-breaking discovery of the common master switch for numerous brain-related diseases.

19 May 2025

Inhaled microplastics suppress pulmonary macrophages critical to the immune system

Microplastics are ubiquitous in the environment, and we all routinely inhale these tiny pollutants. Now new research published at the ATS 2025 International Conference has found that inhaled microplastics suppress pulmonary macrophages, a type of white blood cell found in the lungs that are critical to the immune system.

19 May 2025

Scientists discover how EBV-infected immune cells migrate and invade the brain

Many people are infected with the Epstein-Barr virus (EBV), and most are unaware of it. However, EBV can sometimes cause cancer, and this pathogen also appears to play an important role in multiple sclerosis and other autoimmune diseases.

19 May 2025

Mayo Clinic discovery may help preserve donor hearts longer

A new discovery by Mayo Clinic researchers could mean more donor hearts are available for heart transplant, giving more people a second chance at life.

19 May 2025

B Cell News and Research

Exploring the link between microbial balance and aging mechanisms

Cell Painting technology uncovers flavonoids with potential to treat bladder cancer

Study reveals dual role of TEAD proteins in neural development

New discovery may help explain why some people infected with CHIKV develop severe joint pain

Finnish researchers uncover how to optimize bexmarilimab use in cancer care

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Genetic variations in Prader-Willi syndrome offer key insights into autism and psychosis

Age-related immune decline reduces CAR-T cell therapy efficacy

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

MIT researchers discover new potential drug targets for Alzheimer’s disease

Diabetes drug shows potential in slowing prostate cancer progression

Air pollution fuels artery damage and accelerates heart disease, review finds

Including dessert in diet plans helps reduce cravings and maintain weight loss

Sucralose disrupts male fertility by damaging sperm and altering hormones in animal study

Breakthrough microimager offers new possibilities for internal imaging

What makes H5N1 a pandemic risk and how can we stop it?

Ground-breaking discovery reveals common master switch for brain-related diseases

Inhaled microplastics suppress pulmonary macrophages critical to the immune system

Scientists discover how EBV-infected immune cells migrate and invade the brain

Mayo Clinic discovery may help preserve donor hearts longer

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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