Clinical Trial News and Research

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How potatoes can improve cardiometabolic health in people with Type 2 diabetes

The potato is small enough to fit inside a person's hand yet contains enough nutrients to whittle waistlines and lower blood sugar in adults with Type 2 diabetes.

9 Aug 2024

Low-fat vegan diet outperforms Mediterranean diet in reducing AGEs and achieving weight loss

Eating a low-fat vegan diet reduces harmful inflammatory dietary compounds called advanced glycation end-products (AGEs) by 73%, compared to no reduction on a Mediterranean diet, according to new research by the Physicians Committee for Responsible Medicine published in Frontiers in Nutrition.

9 Aug 2024

New research shows how testosterone may shield against severe Covid-19

A new study has revealed important information about how a patient's testosterone level can help protect them from severe Covid-19.

9 Aug 2024

Alcohol use in older adults linked to increased risk of severe head trauma after falls

Nationally, falls remain the leading cause of both fatal and non-fatal injuries in older adults and are the leading cause of traumatic brain injury.

8 Aug 2024

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

A drug effective in treating breast cancer shows new promise in addressing breast cancer with brain metastases or recurrent glioblastoma, as reported by results of a prospective window-of-opportunity trial at the University of Texas Health Science Center at San Antonio (UT Health San Antonio).

8 Aug 2024

C-Path supports innovative ALS, neurodegenerative disease research with new grant

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) announced today a new research grant awarded to Daniela C. Zarnescu, Ph.D., Professor of Cellular and Molecular Physiology at Penn State University College of Medicine, in collaboration with Jon Njardarson, Ph.D., Professor at the University of Arizona.

8 Aug 2024

Innovative program promotes positive adolescent romantic relationships and use of effective contraceptives

Romantic relationships play an important part in adolescent development. Most young people have had at least one romantic relationship by middle adolescence (ages 14 to17).

8 Aug 2024

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Researchers highlighted the complexities of using amyloid immunotherapy for early Alzheimer's disease, discussing its clinical benefits, challenges, and broader health implications. Despite some positive results, concerns over adverse effects, trial biases, and cost hinder widespread adoption.

7 Aug 2024

Radiotherapy after surgery shown to prevent breast cancer recurrence for up to 10 years

Providing radiotherapy after surgery could prevent breast cancer from returning in the same place for up to 10 years, a long-term study suggests.

7 Aug 2024

Investigational drug shows promise in treating rare blood disease in fetuses

Data from a new investigational drug that could alter the standard treatment for a rare blood disease suggests it has the potential to delay or prevent anemia and the need for intrauterine blood transfusions in babies who are at high risk for the condition, known as Hemolytic Disease of the Fetus and Newborn (HDFN).

7 Aug 2024

New stem cell therapy for heart failure undergoing U.S. clinical trials

A new stem cell therapy for heart failure is being tested in patients at the University of Louisville and UofL Health.

7 Aug 2024

NUS study finds 5-HTP enhances sleep quality and gut health in older adults

National University of Singapore (NUS) nutritionists have found that 5-Hydroxytryptophan (5-HTP) supplementation can improve sleep quality in Singaporean older adults, particularly in individuals with poor sleep patterns, and manage their gut microbiome composition.

7 Aug 2024

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

A new drug for treatment of a type of brain cancer, called IDH-mutant low-grade glioma, was approved Aug. 6 by the U.S. Food and Drug Administration (FDA).

7 Aug 2024

Study highlights the need for language services in cancer trials

Underrepresentation of racial and ethnic minority populations in cancer clinical trials persists partly because translation and interpretation services and resources are unavailable or inadequate in the United States, according to a Children's Oncology Group (COG) study led by Columbia University School of Nursing. The updated study was published online in the Journal of the National Cancer Institute Cancer Spectrum on July 25, 2024, and will appear in the August 2024 journal issue.

7 Aug 2024

FDA approves vorasidenib for Grade 2 gliomas with IDH mutations

Vorasidenib has been approved by the U.S. Food and Drug Administration (FDA) for patients with Grade 2 gliomas with IDH1 or IDH2 mutations.

6 Aug 2024

Analyzing the impact of heart disease treatments on patients with CHIP

Nicholas A. Marston, MD, MPH, of the TIMI Study Group and Carl J. and Ruth Shapiro Cardiovascular Center at Brigham and Women's Hospital, is the corresponding author of a paper published in Nature Medicine, "Clonal hematopoiesis, cardiovascular events and treatment benefit in 63,700 individuals from five TIMI randomized trials."

6 Aug 2024

Omega-3 fatty acids show potential in protecting brain health in older adults

Researchers assess the role of ω-3 polyunsaturated fatty acids (PUFAs) in reducing white matter lesion accumulation and neuronal integrity degeneration.

6 Aug 2024

Refined corn flour and bran blend significantly lowers LDL cholesterol, study reveals

The findings of the randomized crossover clinical trial, available online now and slated to appear in an upcoming issue of the Journal of Nutrition, reveal simply swapping in foods made from refined corn flour + corn bran can lower LDL cholesterol concentrations by anywhere from 5% - 13.3% in just four weeks.

6 Aug 2024

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer.

5 Aug 2024

Breakthrough MS drug uses green mamba venom discovery to promote myelin repair

Ten years of work, and a little help from the green mamba snake, has resulted in a promising new drug that is already being tested in clinical trials.

5 Aug 2024

Clinical Trial News and Research

How potatoes can improve cardiometabolic health in people with Type 2 diabetes

Low-fat vegan diet outperforms Mediterranean diet in reducing AGEs and achieving weight loss

New research shows how testosterone may shield against severe Covid-19

Alcohol use in older adults linked to increased risk of severe head trauma after falls

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

C-Path supports innovative ALS, neurodegenerative disease research with new grant

Innovative program promotes positive adolescent romantic relationships and use of effective contraceptives

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Radiotherapy after surgery shown to prevent breast cancer recurrence for up to 10 years

Investigational drug shows promise in treating rare blood disease in fetuses

New stem cell therapy for heart failure undergoing U.S. clinical trials

NUS study finds 5-HTP enhances sleep quality and gut health in older adults

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

Study highlights the need for language services in cancer trials

FDA approves vorasidenib for Grade 2 gliomas with IDH mutations

Analyzing the impact of heart disease treatments on patients with CHIP

Omega-3 fatty acids show potential in protecting brain health in older adults

Refined corn flour and bran blend significantly lowers LDL cholesterol, study reveals

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Breakthrough MS drug uses green mamba venom discovery to promote myelin repair

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