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Special review highlights benefits of using botulinum neurotoxin for treating facial wrinkles

Botox and other botulinum neurotoxin (BoNT) products are widely known for their use in treating facial wrinkles--but they can also be used to treat a wide range of non-cosmetic problems.

31 Aug 2016

Research strongly links smoking to bowel condition relapses

Smoking is strongly linked to relapse of a serious bowel condition, research has confirmed.

31 Aug 2016

SAGA funding initiative aims to advance understanding of potential sex differences in Alzheimer's

The first-ever Alzheimer's Association Sex and Gender in Alzheimer's research grant awards will provide $2.2 million to nine projects to advance understanding of the disproportionate effect of Alzheimer's disease on women.

31 Aug 2016

Family-based cognitive behavioral therapy may be key to improve sleep in children with ASD

Cognitive behavioral therapy is a short-term form of therapy that focuses on changing how a person thinks about and reacts to specific situations. Used by therapists for decades, it has been proven effective for treating a number of problems including insomnia.

31 Aug 2016

New stem-cell model of heart tissue unravels mechanisms linked to hypertrophic cardiomyopathy

Using advanced stem cell technology, scientists from the Icahn School of Medicine at Mount Sinai have created a model of a heart condition called hypertrophic cardiomyopathy (HCM) — an excessive thickening of the heart that is associated with a number of rare and common illnesses, some of which have a strong genetic component.

31 Aug 2016

Nutrition could be cost-effective treatment to improve health in malnourished older adults

As a majority of older adults have two or more chronic conditions, finding new ways to improve their health and decrease the cost of care is vital to helping them live healthier, longer lives.

30 Aug 2016

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

In an effort to determine if stem cell therapy can prevent or improve a condition called "diabetic foot" caused by poor blood flow in patients with diabetes, a team of researchers in China has found that transplanting human placenta-derived mesenchymal stem cells (MSCs) into rats modeled with diabetes can affect blood vessel growth, potentially improving blood flow and preventing critical limb ischemia (CLI), a condition that results in diabetic foot and frequently leads to amputation.

30 Aug 2016

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

In a study focusing on the role of self-donated (autologous) bone marrow-derived endothelial progenitor cells (EPCs) in placental vascular development, researchers in Japan have discovered that when transplanted into pregnant mice, EPCs can contribute to better blood vessel growth that helps in forming "normalized" placental vascularization, leading, in turn, to reduced recurrent miscarriages by providing a healthier fetal environment during gestation.

30 Aug 2016

Multi-purpose protein may offer clues for successful treatment of Alzheimer's disease

The tidal wave approaches. In the coming decades, Alzheimer's disease is projected to exact a devastating economic and emotional toll on society, with patient numbers in the US alone expected to reach 13.5 million by mid-century at a projected cost of over a trillion dollars.

30 Aug 2016

REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

A clinical decision rule (CDR) that can be applied to women after a first, unprovoked venous thromboembolism (VTE) was able to identify those with a low-risk of recurrence who could safely discontinue anticoagulant therapy, researchers reported at ESC Congress 2016.

30 Aug 2016

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

Previous studies at the University of Colorado Cancer Center show that the experimental drug AMPI-109 potently kills triple-negative breast cancer cells.

30 Aug 2016

New anticoagulant treatment safe and effective for AF patients before cardioversion

Patients with atrial fibrillation (AF) who need anticoagulation before undergoing electrical correction of their abnormal heartbeat (cardioversion) may benefit from treatment with edoxoban - a non-vitamin K antagonist (VKA) oral anticoagulant (NOAC), according to results of the ENSURE-AF trial.

30 Aug 2016

MedUni Vienna scientists aim to identify prognostic markers for cutaneous lymphomas

Primary cutaneous lymphomas, cancers of the lymphatic system, occur in the skin and originate either from T-lymphocytes (T-cell lymphomas, incidence 75%) or in B-cell lymphocytes (B-cell lymphomas, 25%).

30 Aug 2016

New study suggests major change in treatment of significant number of ACS patients

More than one quarter of heart attack patients who are normally treated with stents to re-open their blocked arteries might be able to forgo this procedure and receive anti-thrombotic medications only, according to results of a pilot study.

30 Aug 2016

Penn scientists find striking similarities between human patients with LCA and dogs

Ciliopathies are diseases that affect the cilia, sensory organelles that most mammalian cells possess and which play a critical role in many biological functions.

30 Aug 2016

Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Nebivolol prevents anthracycline-induced cardiotoxicity, according to research presented at ESC Congress 2016 today by Professor Mirela Cleopatra Tomescu, a cardiologist at Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.

30 Aug 2016

Could a light-listening photonics device detect skin disease? An interview with Prof. Vasilis Ntziachristos

Detection of malignant skin alterations is currently aided by optical microscopes such as dermoscopes or optical microscopes. While the latter offers high resolution, it comes with a major disadvantage, just like any other purely microscopic method: it only provides a partial view of the skin due to the low penetration depth.

29 Aug 2016

Therapy News and Research

Special review highlights benefits of using botulinum neurotoxin for treating facial wrinkles

Research strongly links smoking to bowel condition relapses

SAGA funding initiative aims to advance understanding of potential sex differences in Alzheimer's

Family-based cognitive behavioral therapy may be key to improve sleep in children with ASD

New stem-cell model of heart tissue unravels mechanisms linked to hypertrophic cardiomyopathy

Nutrition could be cost-effective treatment to improve health in malnourished older adults

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

Multi-purpose protein may offer clues for successful treatment of Alzheimer's disease

REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

New anticoagulant treatment safe and effective for AF patients before cardioversion

MedUni Vienna scientists aim to identify prognostic markers for cutaneous lymphomas

New study suggests major change in treatment of significant number of ACS patients

Penn scientists find striking similarities between human patients with LCA and dogs

Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Could a light-listening photonics device detect skin disease? An interview with Prof. Vasilis Ntziachristos

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researcher receives NIH grant to detect increasing Mtb activity in people with HIV

Novel drug-dispensing contact lens effective in providing better pressure reduction in glaucoma model

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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