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New insights into cancer cell signaling could help prevent metastases

Research published yesterday in Nature Communications has revealed a previously unknown mechanism by which metastasising cancer cells survive when they break away from the primary tumour. It is hoped that the discovery could help with the development of novel cancer treatments that prevent metastasis.

24 Jun 2016

Gamma-ray irradiation improves safety of stem cell transplantation in Parkinson’s disease patients

Replacing dopamine-producing cells in the brain represents a promising therapeutic approach in Parkinson's disease, and a new study shows how post-transplantation gamma-ray irradiation can reduce the risk of tumor formation.

24 Jun 2016

Centrally assisted collaborative telecare model improves PTSD/depression symptoms in soldiers

Military members who visited a primary care clinic while suffering from post-traumatic stress disorder and depression reported fewer symptoms and better mental health functioning a year after enrolling in a treatment program that included specially trained care managers and telephone therapy options, according to a new study conducted by RTI International, RAND and the Department of Defense Deployment Health Clinical Center.

24 Jun 2016

Taking ipilimumab, nivolumab drugs may increase risk of developing rheumatologic diseases

Case reports on 13 cancer patients suggest that a small number of cancer patients taking the immunotherapy drugs ipilimumab and nivolumab may be at some higher-than-normal risk of developing autoimmune joint and tissue diseases, including inflammatory arthritis, according to a preliminary study by Johns Hopkins Medicine researchers.

24 Jun 2016

Researchers engineer revolutionary new approach to combat cancer treatment resistance

Math, biology and nanotechnology are becoming strange, yet effective bed-fellows in the fight against cancer treatment resistance. Researchers at the University of Waterloo and Harvard Medical School have engineered a revolutionary new approach to cancer treatment that pits a lethal combination of drugs together into a single nanoparticle.

24 Jun 2016

JBMR article highlights controversies in treating high-risk osteoporosis patients

The remarkable progress made over the past 30 years to reduce fractures and dramatically improve the quality of life for millions of osteoporosis patients is rapidly being reversed, say two bone health experts in a Journal of Bone and Mineral Research article published online today.

24 Jun 2016

Researchers use wristband sensors to detect how opioid users in emergency room reacted to dosages

There is merit in looking at the use of wearable biosensors to detect whether opioid users stay focused on their rehabilitation programs.

23 Jun 2016

Neurotherapeutic video game may help improve cognitive abilities in children with genetic disorders

A UC Davis researcher has created a video game for children who experience cognitive impairments from genetic disorders with the hope that that it will improve their ability to mentally process information about space and time.

23 Jun 2016

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier.

23 Jun 2016

Two gene variants provide clue to why some patients with PD respond well to rasagiline drug

Researchers have identified a gene variant which explains why some patients with Parkinson's Disease respond well to drug treatment and other do not.

23 Jun 2016

Study to examine new ways to transfer autistic child's improving communication skills into education setting

A University of Manchester-led study is testing whether an intervention with parents and teachers can help children with autism transfer newly acquired social communication skills from home into school.

23 Jun 2016

Pretreatment smoking linked to poor prognosis in AI-treated patients

Among older aromatase inhibitor (AI)-treated patients with breast cancer, current smokers at treatment initiation have an increased risk of breast cancer events and distant metastases, say Swedish researchers.

23 Jun 2016

'Simple' model predicts PegIFN response in chronic HBV

Chinese researchers have developed a scoring system based on hepatitis B virus-related clinical parameters to predict response to pegylated-interferon in chronic HBV patients.

23 Jun 2016

HCC predictors identified for chronic HBV patients with newly diagnosed cirrhosis

In patients with chronic hepatitis B virus infection who have been newly diagnosed with cirrhosis, the risk of hepatocellular carcinoma development can be ascertained using several clinical and molecular factors, study findings indicate.

23 Jun 2016

Maternal HBsAg can serve as HBV vertical transmission marker

Two studies have independently identified quantitative hepatitis B surface antigen as a marker to identify pregnant women with chronic hepatitis B virus infection whose infants are at high-risk of infection despite immunoprophylaxis.

23 Jun 2016

Novel combination therapy slows cancer growth in patients with advanced solid tumors

A phase 1 clinical trial testing a novel combination therapy developed by scientists at VCU Massey Cancer Center slowed the growth of cancer in the majority of trial participants, which were patients with advanced solid tumors.

22 Jun 2016

Study finds ARNI therapy could potentially prevent 28,484 deaths from heart failure each year

A UCLA-led study estimates that almost 28,500 deaths could be prevented each year in the U.S. through use of a new FDA-approved class of cardiovascular medication that helps reduce mortality in patients diagnosed with heart failure and reduced ejection fraction, the percentage of blood pumped from the heart with each contraction.

22 Jun 2016

Hops show promise in reducing breast cancer risk

Hops, the flower cones used in beer-making, are also found in dietary supplements designed to help treat post-menopausal symptoms and other conditions. Scientists are now investigating whether an extract from the plant could also help fend off breast cancer.

22 Jun 2016

Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

Rituximab may be an attractive treatment option for patients with relapsing-remitting multiple sclerosis, suggest phase II study findings showing its efficacy in controlling inflammatory activity.

22 Jun 2016

Salvage inotuzumab ozogamicin improves ALL outcomes

Compared with standard chemotherapy, treatment with inotuzumab ozogamicin increases the rate of complete remission and allows a higher proportion of patients with relapsed or refractory acute lymphoblastic leukaemia to subsequently receive stem-cell transplantation, research suggests.

22 Jun 2016

Therapy News and Research

New insights into cancer cell signaling could help prevent metastases

Gamma-ray irradiation improves safety of stem cell transplantation in Parkinson’s disease patients

Centrally assisted collaborative telecare model improves PTSD/depression symptoms in soldiers

Taking ipilimumab, nivolumab drugs may increase risk of developing rheumatologic diseases

Researchers engineer revolutionary new approach to combat cancer treatment resistance

JBMR article highlights controversies in treating high-risk osteoporosis patients

Researchers use wristband sensors to detect how opioid users in emergency room reacted to dosages

Neurotherapeutic video game may help improve cognitive abilities in children with genetic disorders

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

Two gene variants provide clue to why some patients with PD respond well to rasagiline drug

Study to examine new ways to transfer autistic child's improving communication skills into education setting

Pretreatment smoking linked to poor prognosis in AI-treated patients

'Simple' model predicts PegIFN response in chronic HBV

HCC predictors identified for chronic HBV patients with newly diagnosed cirrhosis

Maternal HBsAg can serve as HBV vertical transmission marker

Novel combination therapy slows cancer growth in patients with advanced solid tumors

Study finds ARNI therapy could potentially prevent 28,484 deaths from heart failure each year

Hops show promise in reducing breast cancer risk

Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

Salvage inotuzumab ozogamicin improves ALL outcomes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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