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Immune checkpoint cancer therapies may cause rare cardiac side effects linked to unexpected immune response

Combination therapy utilizing two approved immunotherapy drugs for cancer treatment may cause rare and sometimes fatal cardiac side effects linked to an unexpected immune response.

4 Nov 2016

Researchers create detailed blueprints of molecular moving vans that transport zinc everywhere

Zinc is essential for wound healing, for vision, for DNA creation, for our senses of taste and smell, even for sexual health. But despite its importance, scientists have never fully understood the mechanism that moves the mineral through the body - until now.

4 Nov 2016

Fresh insights into immune cell could signal new approach to treating life-threatening lung condition

Fresh insights into a life-threatening lung condition triggered by blood poisoning could signal a new approach to treating the disease, researchers found.

3 Nov 2016

Lack of shrinkage in the hippocampus may help predict people at risk for dementia with Lewy bodies

Dementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzheimer's disease and Parkinson's disease, a correct diagnosis can be difficult.

3 Nov 2016

Researchers identify first two core genes that regulate deep sleep and dreaming

Researchers have identified the first two core genes that regulate the amount of deep sleep and dreaming, a key development they believe will lead to the discovery of a network of related genes controlling sleep.

3 Nov 2016

New questionnaire can predict people who engage in problematic behavior

Researchers in the social sciences have been searching for a holy grail: an accurate way to predict who is likely to engage in problematic behavior, like using drugs.

3 Nov 2016

Safety of generic oncology drugs in developing countries is uncertain, say researchers

Although generic oncology drugs can reduce patient costs and improve treatment access, the safety of these drugs in developing countries is uncertain, according to an international research team led by Dr. Charles Bennett, Josie M. Fletcher professor and chairman of the S.C. SmartState Center in Medication Safety and Efficacy at the College of Pharmacy at the University of South Carolina.

3 Nov 2016

Researchers engineer new weapon to destroy antibiotic-resistant bacteria

Over the past few decades, many bacteria have become resistant to existing antibiotics, and few new drugs have emerged.

2 Nov 2016

Lack of brain shrinkage may help identify people at risk for dementia with Lewy bodies

A lack of shrinkage in the area of the brain responsible for memory may be a sign that people with thinking and memory problems may go on to develop dementia with Lewy bodies rather than Alzheimer's disease, according to a new study published in the November 2, 2016, online issue of Neurology, a medical journal of the American Academy of Neurology.

2 Nov 2016

Mothers in therapy for substance use recover faster if children take part in treatment, study shows

Mothers in therapy for drug and alcohol use recover faster if their children take part in their treatment sessions, according to a first-of-its-kind study.

2 Nov 2016

Shape of blood flow in heart's upper left chamber may help predict stroke risk

Using specialized CT scans of a healthy heart and one with heart disease, a team of Johns Hopkins cardiologists and biomedical engineers say they've created computer models of the "shape" of blood flow through the heart's upper left chamber that someday may help predict stroke risk.

2 Nov 2016

Scientists discover novel therapeutic target and treatment strategy for acute myeloid leukemia

University of Hawai'i Cancer Center researchers discovered a novel therapeutic target and treatment strategy for acute myeloid leukemia, a cancer of the blood and bone marrow that normally requires prompt and aggressive treatment.

2 Nov 2016

Researchers create new culture model of human intestine to study inflammatory bowel disease

Inflammatory bowel disease (IBD) is a complex condition that requires a lifetime of care and increases a person's cancer risk.

2 Nov 2016

TSRI researchers uncover mechanism behind T cell exhaustion

In a new study with broad implications for treating cancers and chronic viral infections, scientists at The Scripps Research Institute (TSRI) have uncovered a mechanism behind a phenomenon called “T cell exhaustion.”

2 Nov 2016

Using deep learning to update the drug discovery paradigm: an interview with Professor Jackie Hunter

With the current drug discovery paradigm, it takes up to 15 years to translate an idea, such as hypothesizing a certain protein is important in a disease and testing this with targeting the protein with a drug, all the way through to proof of concept...

2 Nov 2016

Researchers identify possible trigger of chronic inflammation in people with diabetes

Inflammation is one of the main reasons why people with diabetes experience heart attacks, strokes, kidney problems and other, related complications. Now, in a surprise finding, researchers at Washington University School of Medicine in St. Louis have identified a possible trigger of chronic inflammation.

2 Nov 2016

New review highlights promises and challenges of nanotechnology in neuroscience

Despite the numerous challenges associated with the application of nanotechnology in neuroscience, it promises to have a significant impact on our understanding of how the nervous system works, how it fails in disease, and the development of earlier and less-invasive diagnostic procedures so we can intervene in the pre-clinical stage of neurological disease before extensive neurological damage has taken place.

2 Nov 2016

RESPECT study: PFO closure more beneficial than medical management in reducing recurrent stroke

Final results from the RESPECT trial found that percutaneously closing a patent foramen ovale (PFO) using the Amplatzer PFO Occluder was superior to medical management in the prevention of recurrent ischemic stroke in patients who previously had a cryptogenic stroke.

2 Nov 2016

UGA researchers find new way to improve cancer-killing power of chemotherapy

University of Georgia researchers have found a way to enhance chemotherapy's cancer-killing powers, bringing science one step closer to a more complete cancer treatment.

2 Nov 2016

Researchers explore link between childhood traumas and adult drug use

Children who are sexually abused are nearly five times more likely to inject drugs in adulthood as those who are not — while children who witness violence are about three times more likely — according to new research released today at the American Public Health Association's 2016 Annual Meeting and Expo in Denver.

2 Nov 2016

Drugs News and Research

Immune checkpoint cancer therapies may cause rare cardiac side effects linked to unexpected immune response

Researchers create detailed blueprints of molecular moving vans that transport zinc everywhere

Fresh insights into immune cell could signal new approach to treating life-threatening lung condition

Lack of shrinkage in the hippocampus may help predict people at risk for dementia with Lewy bodies

Researchers identify first two core genes that regulate deep sleep and dreaming

New questionnaire can predict people who engage in problematic behavior

Safety of generic oncology drugs in developing countries is uncertain, say researchers

Researchers engineer new weapon to destroy antibiotic-resistant bacteria

Lack of brain shrinkage may help identify people at risk for dementia with Lewy bodies

Mothers in therapy for substance use recover faster if children take part in treatment, study shows

Shape of blood flow in heart's upper left chamber may help predict stroke risk

Scientists discover novel therapeutic target and treatment strategy for acute myeloid leukemia

Researchers create new culture model of human intestine to study inflammatory bowel disease

TSRI researchers uncover mechanism behind T cell exhaustion

Using deep learning to update the drug discovery paradigm: an interview with Professor Jackie Hunter

Researchers identify possible trigger of chronic inflammation in people with diabetes

New review highlights promises and challenges of nanotechnology in neuroscience

RESPECT study: PFO closure more beneficial than medical management in reducing recurrent stroke

UGA researchers find new way to improve cancer-killing power of chemotherapy

Researchers explore link between childhood traumas and adult drug use

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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