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Right ventricular echocardiography predicts targeted therapy outcome in PAH

Echocardiography re-assessment of right ventricular function after targeted therapy is sufficient to predict subsequent prognosis in patients with pulmonary arterial hypertension, say researchers.

15 Jun 2016

MPC outperforms PID in automated insulin delivery for patients with type 1 diabetes mellitus

The so-called artificial pancreas — an automated insulin delivery system for people with type 1 diabetes mellitus — uses an advanced control algorithm to regulate how much insulin a pump should deliver and when. Regulating glucose is challenging because levels respond to a wide-array of variables, including food, physical activity, sleep, stress, hormones, metabolism and more.

14 Jun 2016

Four miRNAs may hold vital clue to disease progression in gliobastoma

Scientists at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich have developed a new method of predicting disease progression in gliobastoma patients who have undergone standard treatment.

14 Jun 2016

Liposome nanoencapsulation can increase efficacy of bacteriophages in oral phage therapy

Scientists at the Universitat Autònoma de Barcelona and the Catalan Institute for Nanoscience and Nanotechnology have developed a nanoencapsulation system with a liposome coating in order to increase the efficacy of bacteriophages in oral phage therapy.

14 Jun 2016

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Non-small cell lung cancers have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system.

14 Jun 2016

Molecular imaging technique could help optimize radiotherapy dose to combat NETs

Aggressive neuroendocrine cancer is something of a dark horse--a rare, elusive and persevering force linked to discouraging long-term survival rates.

14 Jun 2016

Darapladib drug can protect against vision loss in diabetic patients

Researchers at Queen's University Belfast and University College London have discovered that a drug, originally developed to treat cardiovascular disease, has the potential to reduce diabetes related blindness.

14 Jun 2016

Study provides more insight into treatment options for severe hemophilia A

Families of children with severe hemophilia A may want to take a fresh look at treatment options from human plasma. A study published in the New England Journal of Medicine on May 26 showed that participants who received a recombinant therapy— the present standard in the United States — developed antibodies or "inhibitors" to the treatments at almost twice the rate as those whose treatments were made from human plasma.

14 Jun 2016

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Cisplatin is a common, powerful chemotherapy agent used for a wide range of cancers such as breast, ovarian and lung, that in a handful of days can also permanently damage or destroy patients' kidneys.

14 Jun 2016

Autologous stem cell transplant safe, effective for HIV-associated lymphoma patients

New research published online today in Blood Journal of the American Society of Hematology (ASH), challenges the generally held belief that individuals with HIV and aggressive lymphoma are not candidates for standard treatment.

14 Jun 2016

U-M researchers explore new way to improve cognitive issues in MS patients

Multiple sclerosis looks different from person to person. In many individuals, though, the difficulty in maintaining a sense of self and in keeping up intellectually can be the disease's most devastating manifestations.

14 Jun 2016

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

Alzheimer's is a devastating and incurable disease marked by beta-amyloid and tau protein aggregations in the brain, yet the direct relationship between these proteins and neurodegeneration has remained a mystery.

14 Jun 2016

Study underscores importance of developing PRMT5 inhibitors as promising treatment for GB patients

A new study suggests that blocking an enzyme called PRMT5 in tumor cells could be a promising new strategy for the treatment of glioblastoma (GB), the most aggressive and lethal form of brain cancer.

14 Jun 2016

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

A study in the Journal of the American Society of Nephrology suggests a new therapeutic approach to treat the development of chronic kidney disease secondary to chronic heart failure, known as cardiorenal syndrome type 2.

14 Jun 2016

Study opens up new strategy to make immunotherapy more effective for different cancer types

By combining local radiation therapy and anti-cancer vaccines with checkpoint inhibitors, researchers from the University of Chicago, working with mice, were able to increase the response rate for these new immunotherapy agents.

14 Jun 2016

Genetic blood test can help predict patient’s respone to neuroendocrine cancer therapy

Malignant neuroendocrine tumors (NETs) are relatively rare, notoriously difficult to treat, and associated with poor long-term survival. According to research presented at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, an investigative blood test could predict how patients will respond to peptide receptor radionuclide therapy (PRRT) before they commit to a course of treatment.

14 Jun 2016

Nearly half of newly-infected HIV patients experience neurologic issues

A team led by researchers from UCSF and Yale has found that half of people newly infected with HIV experience neurologic issues. These neurologic findings are generally not severe and usually resolve after participants started anti-retroviral therapy.

14 Jun 2016

Novel radioimmunotherapy may help cure colorectal cancer

An emerging cancer therapy has colorectal tumors surrounded. Presenters at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging are unveiling a novel radioimmunotherapy that combines a cancer-seeking antibody with potent radionuclide agents, resulting in complete remission of colorectal cancer in mouse models.

14 Jun 2016

Age no barrier to vorapaxar use in ACS

The protease-activated receptor 1 inhibitor vorapaxar offers the same benefits to older and younger patients with non-ST segment elevation acute coronary syndromes, shows further analysis of the TRACER trial.

14 Jun 2016

'Hypertensive urgency' may cause unnecessary alarm

Patients with a very high blood pressure reading in the absence of other symptoms are highly unlikely to have a major adverse cardiovascular event within the next 6 months, researchers report.

14 Jun 2016

Therapy News and Research

Right ventricular echocardiography predicts targeted therapy outcome in PAH

MPC outperforms PID in automated insulin delivery for patients with type 1 diabetes mellitus

Four miRNAs may hold vital clue to disease progression in gliobastoma

Liposome nanoencapsulation can increase efficacy of bacteriophages in oral phage therapy

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Molecular imaging technique could help optimize radiotherapy dose to combat NETs

Darapladib drug can protect against vision loss in diabetic patients

Study provides more insight into treatment options for severe hemophilia A

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Autologous stem cell transplant safe, effective for HIV-associated lymphoma patients

U-M researchers explore new way to improve cognitive issues in MS patients

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

Study underscores importance of developing PRMT5 inhibitors as promising treatment for GB patients

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

Study opens up new strategy to make immunotherapy more effective for different cancer types

Genetic blood test can help predict patient’s respone to neuroendocrine cancer therapy

Nearly half of newly-infected HIV patients experience neurologic issues

Novel radioimmunotherapy may help cure colorectal cancer

Age no barrier to vorapaxar use in ACS

'Hypertensive urgency' may cause unnecessary alarm

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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