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New drug appears to decrease inflammation in the brain linked to Alzheimer's disease

An experimental drug shows promise in treating Alzheimer's disease by preventing inflammation and removing abnormal protein clumps in the brain that are associated with the disease, suggests a study in mice presented at the ANESTHESIOLOGY 2016 annual meeting.

25 Oct 2016

GAFFI: Access to rapid diagnostics, antifungals could prevent over a million AIDS-related deaths by 2020

Fungal infection causes around half of AIDS-related deaths, of which there were 1,100,000 in 2015. A first of its kind analysis – ‘Modelling reduction in AIDS deaths’ by the University of Manchester’s Professor David W Denning and published today in Philosophical Transactions of the Royal Society B – suggests that the opportunity to save lives is being missed.

25 Oct 2016

New report puts forward recommendations aimed at speeding up access to innovative dementia medicines

A new report published by the government today (24 October), puts forward a number of recommendations aimed at speeding up the process by which the NHS implements newly developed drugs and medical procedures.

25 Oct 2016

Researchers design small compounds with potential to correct mitochondrial dysfunction

Charcot-Marie-Tooth disease is an inherited disorder that leads to a gradual loss of motor neurons and, eventually, paralysis. The condition is caused by genetic mutations that disrupts cells' energy factories, called mitochondria.

25 Oct 2016

New initiative aims to prevent opioid addition among surgical patients in Michigan

America's opioid drug epidemic has struck hard in Michigan. But now, a team from the University of Michigan is striking back at a key factor: opioid prescriptions for patients before and after surgery.

25 Oct 2016

Highly caffeinated alcoholic drinks may induce changes in the adolescent brain similar to cocaine

Drinking highly caffeinated alcoholic beverages triggers changes in the adolescent brain similar to taking cocaine, and the consequences last into adulthood as an altered ability to deal with rewarding substances, according to a Purdue University study.

25 Oct 2016

Salk researchers develop new computer program to measure blepharosplasm severity

If two clinicians observe the same patient with blepharospasm -- uncontrollable muscle contractions around the eye -- they'll often come away with two different conclusions on the severity of the patient's symptoms.

24 Oct 2016

New approach could overcome large immunosuppressive tumors

Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality.

24 Oct 2016

TSRI scientists discover reason for lack of successful HCV vaccine design

Researchers have been trying for decades to develop a vaccine against the globally endemic hepatitis C virus (HCV). Now scientists at The Scripps Research Institute have discovered one reason why success has so far been elusive.

24 Oct 2016

Boosting levels of detoxification compound may help prevent metabolic decline linked to aging

Researchers at Oregon State University have found that a specific detoxification compound, glutathione, helps resist the toxic stresses of everyday life - but its levels decline with age and this sets the stage for a wide range of age-related health problems.

24 Oct 2016

Tackling antimicrobial resistance by turning ideas into action

“This is our moment to tackle antimicrobial resistance (AMR),” declared Ed Whiting, Head of Policy and Chief of Staff, Wellcome Trust, London at Antibiotic Research UK’s inaugural lecture held at Portcullis House, Westminster today. Ed’s pragmatic discussion mirrored the theme of the event: turning ideas in action.

24 Oct 2016

Combination of two drugs could be effective strategy to target T-cell lymphocytic leukemia

Researchers have determined that two Phase 1 drugs (CX-4945 and JQ1) can work together to efficiently kill T-cell acute lymphoblastic leukemia cells while having minimal impact on normal blood cells.

24 Oct 2016

Fission yeast could help discover novel cancer drugs

Cancer is a notoriously difficult disease to treat. Not only do a wide variety of cancers exist, requiring specialized treatments for each type, but cancer cells within an individual can morph and render previously potent therapeutics ineffective.

24 Oct 2016

Danish researchers develop new method to study distribution of tracer in tumours

A Danish research team is behind a new method for studying how a tracer is distributed in a cancer tumour via its extensive vascular network.

24 Oct 2016

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

A table-top device that enables medical staff to genetically manipulate a patient's blood to deliver potential new therapies for cancer, HIV and other diseases would eliminate the need for multi-million-dollar "clean rooms," making gene therapy more possible for even the poorest of countries.

24 Oct 2016

Drugs News and Research

New drug appears to decrease inflammation in the brain linked to Alzheimer's disease

GAFFI: Access to rapid diagnostics, antifungals could prevent over a million AIDS-related deaths by 2020

New report puts forward recommendations aimed at speeding up access to innovative dementia medicines

Researchers design small compounds with potential to correct mitochondrial dysfunction

New initiative aims to prevent opioid addition among surgical patients in Michigan

Highly caffeinated alcoholic drinks may induce changes in the adolescent brain similar to cocaine

Salk researchers develop new computer program to measure blepharosplasm severity

New approach could overcome large immunosuppressive tumors

TSRI scientists discover reason for lack of successful HCV vaccine design

Boosting levels of detoxification compound may help prevent metabolic decline linked to aging

Tackling antimicrobial resistance by turning ideas into action

Combination of two drugs could be effective strategy to target T-cell lymphocytic leukemia

Fission yeast could help discover novel cancer drugs

Danish researchers develop new method to study distribution of tracer in tumours

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

Scientists discover new option for treating malignant pleural mesothelioma

Novel lipid-based therapeutic shows promise for combating drug resistance in AML

Novel approach may speed up development of new drugs against skin disease

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

New research examines use of nanotechnology to improve delivery of drugs to HIV patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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