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Researchers uncover how rogue immune cells gain access to neurons in multiple sclerosis

Drug designers working on therapeutics against multiple sclerosis should focus on blocking two distinct ways rogue immune cells attack healthy neurons, according to a new study in the journal Cell Reports.

21 Nov 2017

Simple test could help predict best treatment for cystic fibrosis patients

Several cutting-edge treatments have become available in recent years to correct the debilitating chronic lung congestion associated with cystic fibrosis. While the new drugs are life-changing for some patients, they do not work for everyone.

21 Nov 2017

Unusual snapping turtle study enhances understanding of congenital lung abnormality

A study of an unusual snapping turtle with one lung found shared characteristics with humans born with one lung who survive beyond infancy. Digital 3D anatomical models created by Emma Schachner, PhD, Assistant Professor of Cell Biology & Anatomy at LSU Health New Orleans School of Medicine, made the detailed research possible.

21 Nov 2017

New research shows how a gene can fuel obesity in mice

Obesity is often attributed to a simple equation: People are eating too much and exercising too little. But evidence is growing that at least some of the weight gain that plagues modern humans is predetermined.

16 Nov 2017

SUNY Downstate professor receives two awards to support research on vision-threatening diseases

Brahim Chaqour, PhD, professor of cell biology and ophthalmology at SUNY Downstate Medical Center, has received two awards to support research into treatment of currently incurable vision-threatening diseases. The new awards, totaling $2,008,973, are from the National Eye Institute of the National Institutes of Health.

14 Nov 2017

Researchers use novel computational tool to understand complex disease processes

Hypertension and heart disease arise from many contributing and interacting factors: genetics, food, and exercise, as well as problems with heart, liver, or kidney function.

14 Nov 2017

Epigenetic editing in healthy breast cells can set off chain reaction for tumor initiation

Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to begin a chain reaction and become abnormal, according to research by Queen Mary University of London.

13 Nov 2017

Study shows promise and potential risk in reversing hearing loss using inner ear stem cells

Want to restore hearing by injecting stem cells into the inner ear? Well, that can be a double-edged sword.

7 Nov 2017

Johns Hopkins scientists report first-ever creation of protein hydrogels inside living cells

Johns Hopkins cell biologists report what they believe is the first-ever creation of tiny protein-based gelatin-like clumps called hydrogels inside living cells.

7 Nov 2017

Study demonstrates for the first-time neurons moving in postnatal neurogenesis

A study published recently in the Journal of Cell Biology has described how newborn precursor neurons, termed neuroblasts, which originated in a permanent pocket of stem cells in an area of the brain called the V-SVZ—traveled from their birthplace to a target destination in the olfactory bulb via a special tunnel called the RMS.

3 Nov 2017

An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections

There are about 77,000 people known to have cystic fibrosis. That's from the various cystic fibrosis registries available globally. The World Health Organization suggests that this number may be low, because there's no reporting on cystic fibrosis from the developing world. The accepted number, at the moment, is about 80,000. That's the one that is used for most of the work that's being done on cystic fibrosis.

From Neem Biotech 3 Nov 2017

Cleveland Clinic researcher awarded $2.6 million grant to create innovative models of colorectal cancer

Cleveland Clinic researcher Emina Huang, M.D., a colorectal surgeon in the Digestive Disease and Surgery Institute and a staff member in the Lerner Research Institute's Department of Stem Cell Biology and Regenerative Medicine, has been awarded a collaborative five-year, $2.6 million grant from the National Cancer Institute to create innovative models of colorectal cancer that will enhance understanding of how the disease develops and spreads.

31 Oct 2017

Inner workings of cells probed by new Kleindiek nanomanipulator at UNSW

The mechanism of how cells work is key to understanding how tumours metastasize as well as tissue regeneration and other bodily functions. The process of mechanotransduction, or how a cell converts a physical stimuli into an electrical response is fundamental to these understandings.

From AXT Pty Ltd 30 Oct 2017

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Several patients with recurring glioblastoma, a deadly brain cancer, survived for more than a year in a clinical trial believed to be the first to use comprehensive DNA and RNA sequencing of a patient's tumor to inform treatment for these patients in real-time.

27 Oct 2017

Scientists get one step closer to reversing retinal degenerative diseases

Degenerative disorders affecting the retinal pigment epithelium (RPE), such as age-related macular degeneration and autosomal recessive bestrophinopathy, can ultimately lead to blindness. Some of these life-changing disorders are the result of mutations in a single gene, called BEST1.

25 Oct 2017

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

The genome editing tool known as CRISPR/Cas9 has opened many doors for biomedical research by allowing scientists to precisely edit DNA sequences and alter function. The technology offers hope for correcting genetic defects and preventing disease.

24 Oct 2017

APC gene mutations play dual role in development of colorectal cancer, research suggests

Adenomatous polyposis coli (APC) is a gene whose mutations are associated with a rare, hereditary form of colorectal cancer known as familial adenomatous polyposis. Research led by scientists at the Institut Pasteur and Inserm have recently demonstrated that mutations to this gene do not only lead to the emergence of colon polyps; they also harm the immune system, leaving it unable to tackle inflammation of the colonic mucosa.

24 Oct 2017

Researchers map molecular events that direct cells' energy metabolism down the cancerous path

As cells with a propensity for cancer break down food for energy, they reach a fork in the road: They can either continue energy production as healthy cells, or shift to the energy production profile of cancer cells.

24 Oct 2017

Measuring biological samples using SNAP

My group is interested in host pathogen interaction and we mainly focus on how bacteria enter cells. In essence, the idea is that if you can prevent bacteria from entering cells, then you will prevent illness.

From Bruker Nano Surfaces and Metrology 24 Oct 2017

Queen's University Belfast leads new research to better understand biology of prostate cancer

Queen's University Belfast has led the world's largest research study using a diagnostic test developed by Almac Diagnostics, to better understand the biology of prostate cancer tumors, which could lead to a transformation in how prostate cancer is diagnosed and treated.

23 Oct 2017

Cell Biology News and Research

Researchers uncover how rogue immune cells gain access to neurons in multiple sclerosis

Simple test could help predict best treatment for cystic fibrosis patients

Unusual snapping turtle study enhances understanding of congenital lung abnormality

New research shows how a gene can fuel obesity in mice

SUNY Downstate professor receives two awards to support research on vision-threatening diseases

Researchers use novel computational tool to understand complex disease processes

Epigenetic editing in healthy breast cells can set off chain reaction for tumor initiation

Study shows promise and potential risk in reversing hearing loss using inner ear stem cells

Johns Hopkins scientists report first-ever creation of protein hydrogels inside living cells

Study demonstrates for the first-time neurons moving in postnatal neurogenesis

An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections

Cleveland Clinic researcher awarded $2.6 million grant to create innovative models of colorectal cancer

Inner workings of cells probed by new Kleindiek nanomanipulator at UNSW

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Scientists get one step closer to reversing retinal degenerative diseases

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

APC gene mutations play dual role in development of colorectal cancer, research suggests

Researchers map molecular events that direct cells' energy metabolism down the cancerous path

Measuring biological samples using SNAP

Queen's University Belfast leads new research to better understand biology of prostate cancer

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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